- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- T-cell and Retrovirus Studies
- Coronary Interventions and Diagnostics
- Cardiovascular and exercise physiology
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Thermoregulation and physiological responses
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Lysosomal Storage Disorders Research
- Blood Pressure and Hypertension Studies
- Vector-Borne Animal Diseases
- Cardiac Ischemia and Reperfusion
- Infrared Thermography in Medicine
- Congenital Heart Disease Studies
- Atherosclerosis and Cardiovascular Diseases
- Pulmonary Hypertension Research and Treatments
Dokkyo Medical University
2014-2021
Kagoshima University
2008-2017
Kagoshima University Hospital
1995-2017
Impact
2016
Smith-Kettlewell Eye Research Institute
2014
American College of Cardiology
2006-2011
Institut des Maladies Métaboliques et Cardiovasculaires
2004-2006
American Heart Association
1984-2006
Massachusetts General Hospital
2003-2006
Kagoshima City Hospital
2003-2005
Although studies have suggested that "late-onset" hypertrophic cardiomyopathy (HCM) may be caused by sarcomeric protein gene mutations, the cause of HCM in majority patients is unknown. This study determined prevalence a potentially treatable hypertrophy, Anderson-Fabry disease, referral population.Plasma alpha-galactosidase A (alpha-Gal) was measured 79 men with who were diagnosed at > or =40 years age (52.9+/-7.7 years; range, 40-71 years) and 74 <40 (25.9+/-9.2 8-39 years). Five (6.3%)...
Using wide-angle, phased-array, two-dimensional echocardiography, mitral leaflets and their annular attachments were recorded from a view close to the standard apical four-chamber view. The transducer was rotated recordings made at 30 degrees rotational intervals around circumference of valve annulus. To reconstruct annulus, diameters (chords) each interval arranged reference point. This done for 12 times during cardiac cycle. Annular areas planimetered circumferences measured. Correlation...
Left ventricular scanning by echocardiography and ultrasono-cardiotomography was performed to search the possible muscular abnormality in 9 cases with giant T wave inversion without documented cause. The deeply inverted more than 1.2mV (average 1.63mV) left precordial leads. All had electrocardiographic hypertrophy of obscure origin ischemic episode absent. Conventional echo beam direction measure short axis ventricle disclosed almost normal thickness movement both interventricular septum...
A warm-water bath (WWB) or sauna (SB) has generally been considered inappropriate for patients with severe congestive heart failure (CHF). However, a comprehensive investigation of the hemodynamic effects thermal vasodilation in CHF not previously undertaken.To investigate acute CHF, we studied 34 chronic (mean age, 58 +/- 14 years). Clinical stages were New York Heart Association functional class II 2, III 19, and IV 13 patients. Mean ejection fraction was 25 9%. After Swan-Ganz catheter...
We sought to elucidate the mechanism of mitral regurgitation (MR) in dilated cardio- myopathy (DCM).Quantitative two-dimensional echocardiographic examinations were performed 27 patients, 18 with DCM (nine MR on physical examination, nine without MR) and underlying heart disease.The "no MR" patients clinically comparable.Spatial recon- structions from multiple apical cross sections used estimate leaflet area needed occlude orifice for a given midsystolic coaptation configuration (LEAF), as...
The tricuspid valve leaflets and their annular attachments were recorded by two-dimensional echocardiography from a view of the right ventricular inflow tract obtained placing transducer at an intermediate position between left apex lower sternal border. was rotated, recordings made 30 degrees rotational intervals around circumference annulus. cyclical pattern variations in size studied with 12 measurements during cardiac cycle five normal subjects. Annular areas circumferences measured....
The effects and reliability of a simple method contrast two-dimensional echocardiographic delineation myocardium after intracoronary injections were evaluated in closed-chest dogs. Multiple an agitated saline-Renografin (meglumine diatrizoate) mixture (3:2 ratio, 2-ml bolus) into the left main coronary artery as well at different sites anterior descending circumflex arteries studied several short-axis long-axis cross sections ventricle. These opacified specific regions ventricular depending...
Background— Surgical annuloplasty can potentially hoist the posterior annulus anteriorly, exaggerate leaflet (PML) tethering, and lead to recurrent ischemic/functional mitral regurgitation (MR). Characteristics of configurations in late postoperative MR were investigated. Methods Results— In 30 patients with surgical for ischemic 20 controls, anterior (AML) PML tethering angles relative line connecting annuli, apical displacement coaptation grade measured by echocardiography before, early...
Background The brachial - ankle pulse wave velocity (baPWV) is used to evaluate the degree of atherosclerosis and arterial distensibility, but its major limitation that it affected by changes in blood pressure (BP) during measurement. Recently, a new atherosclerotic index, cardio-ankle vascular index (CAVI), has been developed measuring PWV BP. CAVI adjusted for BP based on stiffness parameter β should measure independent purpose this study was validity compared with baPWV, reproducibility...