A5103127779- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Nuclear reactor physics and engineering
- Ultrasound and Hyperthermia Applications
- Steroid Chemistry and Biochemistry
- Dark Matter and Cosmic Phenomena
- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Estrogen and related hormone effects
- Synthesis of heterocyclic compounds
- Synthesis and Reactions of Organic Compounds
- Neutrino Physics Research
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Biological Evaluation
- Phytochemical Studies and Bioactivities
- Oxidative Organic Chemistry Reactions
- Medical Imaging Techniques and Applications
- Ultrasound in Clinical Applications
- Particle accelerators and beam dynamics
- Sulfur-Based Synthesis Techniques
- Cosmology and Gravitation Theories
- Muon and positron interactions and applications
- Phenothiazines and Benzothiazines Synthesis and Activities
Stanford University
2012-2017
University of Washington
2014-2017
LAC+USC Medical Center
2016
The University of Adelaide
2013-2015
Seattle University
2014-2015
University of Manchester
2011-2013
Ludwig-Maximilians-Universität München
2012
European Organization for Nuclear Research
2011
The University of Tokyo
2003-2007
Tokyo University of Science
2003-2007
In compressed sensing, one takes samples of an N -dimensional vector using matrix A , obtaining undersampled measurements . For random matrices with independent standard Gaussian entries, it is known that, when k -sparse, there a precisely determined phase transition: for certain region in the ( )-phase diagram, convex optimization typically finds sparsest solution, whereas outside that region, fails. It has been shown empirically same property—with transition location—holds wide range...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMass spectrometry in structural and stereochemical problems. CXLIX. Question of ring expansion the fragmentation carbon-13 nitrogen heterocyclesMichael Marx Carl DjerassiCite this: J. Am. Chem. Soc. 1968, 90, 3, 678–681Publication Date (Print):January 1, 1968Publication History Published online1 May 2002Published inissue 1 January 1968https://pubs.acs.org/doi/10.1021/ja01005a022https://doi.org/10.1021/ja01005a022research-articleACS...
With the discovery of Higgs boson, spectrum particles in Standard Model (SM) is complete. It more important than ever to perform precision measurements and test for deviations from SM predictions electroweak sector. In this report, we investigate two themes arena measurements: observables (EWPOs) that particle content couplings minimal supersymmetric SM, involving multiple gauge bosons final state which provide unique probes basic tenets symmetry breaking. Among EWPOs focus our discussion on...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactivity-selectivity in the Swern oxidation of alcohols using dimethyl sulfoxide-oxalyl chlorideMichael Marx and Thomas T. TidwellCite this: J. Org. Chem. 1984, 49, 5, 788–793Publication Date (Print):March 1, 1984Publication History Published online1 May 2002Published inissue 1 March 1984https://pubs.acs.org/doi/10.1021/jo00179a009https://doi.org/10.1021/jo00179a009research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSix-membered rings via olefin participation in the opening of acylcyclopropanesGilbert Stork and Michael MarxCite this: J. Am. Chem. Soc. 1969, 91, 9, 2371–2373Publication Date (Print):April 1, 1969Publication History Published online1 May 2002Published inissue 1 April 1969https://pubs.acs.org/doi/10.1021/ja01037a031https://doi.org/10.1021/ja01037a031research-articleACS PublicationsRequest reuse permissionsArticle Views338Altmetric-Citations39LEARN...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT16α-Hydroxy Steroids. VII.1 The Isomerization of TriamcinoloneLeland L. Smith, Michael Marx, John J. Garbarini, Theodore Foell, Victor E. Origoni, and Joseph GoodmanCite this: Am. Chem. Soc. 1960, 82, 17, 4616–4625Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/ja01502a043https://doi.org/10.1021/ja01502a043research-articleACS...
Purpose: MR thermometry is critical for safe and effective transcranial focused ultrasound.The current single-slice sequence cannot achieve all desired treatment monitoring requirements.We propose an approach in which the imaging requirements of different aspects are met by optimizing multiple sequences.Methods: Imaging were determined three stages MR-guided ultrasound brain treatment: 1) focal spot localization, 2) monitoring, 3) background monitoring.Multiple-echo spiral sequences...
Purpose: To study the phase aberrations produced by human skulls during transcranial magnetic resonance imaging guided focused ultrasound surgery (MRgFUS), to demonstrate potential of Zernike polynomials (ZPs) accelerate adaptive focusing process, and investigate benefits using corrections obtained in previous studies provide initial guess for correction a new data set. Methods: The five aberration sets, analyzed here, were calculated based on preoperative computerized tomography (CT) images...
The cardiac ankyrin repeat protein (CARP), a nuclear transcription co-factor that negatively regulates gene expression, is increased in human heart failure and animal models of hypertrophy. mechanism by which CARP expression regulated the consequences overexpression on contractility are unknown.Compared to vehicle treated controls, 4-day treatment male Wistar rats with beta-adrenoceptor agonist isoprenaline (2.4 mg/kg per day) induced hypertrophy significantly mRNA levels left ventricles....
A series of 4(6)- and 5-phenyl-substituted 2-amino- 2-[(alkoxycarbonyl)amino]-1,4,5,6-tetrahydropyrimidines were prepared evaluated for central nervous system (CNS) effects in animal models. Several compounds possessed potent antidepressant activity all this devoid significant any the other CNS (anticonvulsant, muscle relaxant, depressant) assays. The most active compound vivo screen (reversal reserpine-induced hypothermia), 2-[(methoxycarbonyl)amino]-5-phenyl-1,4,5,6-tetrahydropyrimidine...
MR temperature monitoring is an indispensable tool for high intensity focused ultrasound. In this paper, a new technique known as MASTER (multiple adjacent slice thermometry with excitation refocusing) presented which improves the speed and accuracy of multiple-slice thermometry. Defocusing magnetization after exciting allows multiple slices to be excited concurrently stored in k-space. The from each then refocused read sequence. This approach increases TE slice, greatly improving SNR...
Purpose Low‐bandwidth PRF shift thermometry is used to guide HIFU ablation treatments. Low sampling bandwidth needed for high signal‐to‐noise ratio with short acquisition times, but can lead off‐resonance artifacts. In this work, improved multiple‐echo presented that allows and reduced It also demonstrated spiral sampling, improve the trade‐off between resolution, speed, measurement precision. Methods Four sequences were tested in vivo, one using two‐dimensional Fourier transform (2DFT)...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThiol esters from steroid 17.beta.-carboxylic acids: carboxylate activation and internal participation by 17.alpha.-acylatesDenis J. Kertesz Michael MarxCite this: Org. Chem. 1986, 51, 12, 2315–2328Publication Date (Print):June 1, 1986Publication History Published online1 May 2002Published inissue 1 June 1986https://pubs.acs.org/doi/10.1021/jo00362a028https://doi.org/10.1021/jo00362a028research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT16α-Hydroxy Steroids. XII.1a21-Amino Derivatives of 9α-FluorohydrocortisoneLeland L. Smith, Michael. Marx, Harold. Mendelsohn, Theodore. Foell, and Joseph J. GoodmanCite this: Am. Chem. Soc. 1962, 84, 7, 1265–1270Publication Date (Print):April 1, 1962Publication History Published online1 May 2002Published inissue 1 April 1962https://pubs.acs.org/doi/10.1021/ja00866a042https://doi.org/10.1021/ja00866a042research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTerpenoids. LX. Revised structures of the cactus triterpene lactones stellatogenin and thurberogeninMichael Marx, Jean Leclercq, Bernard Tursch, Carl DjerassiCite this: J. Org. Chem. 1967, 32, 10, 3150–3155Publication Date (Print):October 1, 1967Publication History Published online1 May 2002Published inissue 1 October 1967https://pubs.acs.org/doi/10.1021/jo01285a048https://doi.org/10.1021/jo01285a048research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT16α-Hydroxy Steroids. VIII.1 16α,17α-Cyclic Orthoesters of TriamcinoloneLeland L. Smith and Michael MarxCite this: J. Am. Chem. Soc. 1960, 82, 17, 4625–4629Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/ja01502a044https://doi.org/10.1021/ja01502a044research-articleACS PublicationsRequest reuse permissionsArticle...
Evaluate whether a decrease in apparent diffusion coefficient (ADC), associated with loss of tissue viability (LOTV), can be observed during the course thermal ablation prostate.Thermal was performed healthy vivo canine prostate model (N = 2, ages: 5 yr healthy, mixed breed, weights: 13-14 kg) using transurethral high-intensity ultrasound catheter and monitored strategy that interleaves weighted images gradient-echo images. The two sequences were used to measure ADC changes temperature...
The in vitro antineoplastic activity of many phosphorus-containing (e.g., phosphocholines) and non-phosphorus-containing quaternary ammonium salts) ether lipids has been evaluated the HL-60 promyelocytic cell line. These compounds are analogues ET-18-OMe (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine). Structural modification 1-(alkylamido)-, -(alkylthio)-, -(alkyloxy)propyl backbones provided further insight into structure-activity relationships these lipids. In this study, a long...
The synthesis of carboxylic and (thio)carbonate esters 1-[2-hydroxy(mercapto)-2-phenylethyl]-1-H-imidazoles, some which are formally related to miconazole its analogues by replacement an ether with ester linkage, is described. In antifungal bioassays a number compounds display in vitro and, few cases, vivo activities comparable that miconazole. this series lipophilicity within relatively narrow range shown be necessary, although not sufficient, criterion for particular, activity.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and central nervous system properties of 2-[(alkoxycarbonyl)amino]-4(5)-phenyl-2-imidazolinesKlaus Weinhardt, Colin C. Beard, Charles Dvorak, Michael Marx, John Patterson, Adolph Roszkowski, Margery Schuler, Stefan H. Unger, Paul J. Wagner, Marshall B. WallachCite this: Med. Chem. 1984, 27, 5, 616–627Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1...
A. V. Robertson, M. Marx and C. Djerassi, Chem. Commun. (London), 1968, 414 DOI: 10.1039/C19680000414