A5101562434- Spinal Cord Injury Research
- Congenital Heart Disease Studies
- Reproductive System and Pregnancy
- Inflammatory Myopathies and Dermatomyositis
- SARS-CoV-2 and COVID-19 Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Endometriosis Research and Treatment
- Immune Cell Function and Interaction
- Pain Mechanisms and Treatments
- Reproductive Biology and Fertility
- Head and Neck Surgical Oncology
- Gestational Diabetes Research and Management
- Rheumatoid Arthritis Research and Therapies
- Neurological Disease Mechanisms and Treatments
- Oral and Maxillofacial Pathology
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Uterine Myomas and Treatments
- SARS-CoV-2 detection and testing
- Folate and B Vitamins Research
- Spine and Intervertebral Disc Pathology
- Gynecological conditions and treatments
- Monoclonal and Polyclonal Antibodies Research
- Ovarian function and disorders
- Scoliosis diagnosis and treatment
Shanghai University of Traditional Chinese Medicine
2025
Huashan Hospital
2025
Fudan University
2025
Zhejiang Chinese Medical University
2025
Jiaxing University
2025
Zhengzhou University
2024
Tongji University
2010-2024
Tongji Hospital
2010-2024
Sir Run Run Shaw Hospital
2014-2024
Zhejiang University
2014-2024
Abstract Continuous evolution of Omicron has led to a rapid and simultaneous emergence numerous variants that display growth advantages over BA.5 (ref. 1 ). Despite their divergent evolutionary courses, mutations on receptor-binding domain (RBD) converge several hotspots. The driving force destination such sudden convergent its effect humoral immunity remain unclear. Here we demonstrate these can cause evasion neutralizing antibody drugs convalescent plasma, including those from breakthrough...
Abstract Continuous evolution of Omicron has led to a rapid and simultaneous emergence numerous variants that display growth advantages over BA. 5. Despite their divergent evolutionary courses, mutations on receptor-binding domain (RBD) converge several hotspots. The driving force destination such convergent its impact humoral immunity remain unclear. Here, we demonstrate these can cause striking evasion neutralizing antibody (NAb) drugs convalescent plasma, including those from BA.5...
Abstract The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19 vaccine compositions. However, immune imprinting induced by vaccination based on ancestral (hereafter referred as WT) strain would compromise antibody response Omicron-based boosters 1–5 . Vaccination strategies counter are critically needed. Here we investigated degree and dynamics in mouse models human cohorts, especially focusing role repeated Omicron stimulation. In mice, efficacy single...
Objective To characterize the ovarian reserve indicators for premature insufficiency (POI) at different disease stages and with various etiologies. Methods According to FSH levels menstrual conditions, patients normal (NOR 5 IU/L<FSH<10 IU/L, n=987), precursor stage of POI (pre-POI 10 IU/L<FSH ≤ 25 n=410), early (25 40 IU/L n=147), failure (POF FSH>40 n=454) were retrospectively screened their records abstracted from Reproductive Hospital Affiliated Shandong...
Unresponsive thin endometrium caused by Asherman syndrome (AS) is the major cause of uterine infertility. However, current therapies are ineffective. This study to evaluate effect transplantation with collagen scaffold/umbilical cord mesenchymal stem cells (CS/UC-MSCs) on this refractory disease.Eighteen infertile women unresponsive endometrium, whose frozen-thawed embryo transfers (FETs) were cancelled due reduced endometrial thickness (ET ≤ 5.5 mm), enrolled in before and after...
Abstract The continuous emergence of highly immune evasive SARS-CoV-2 variants, like XBB.1.5 and XBB.1.16, highlights the need to update COVID-19 vaccine compositions. However, imprinting induced by wildtype (WT)-based vaccination would compromise antibody response Omicron-based boosters. Vaccination strategies that can counter are critically needed. In this study, we investigated degree dynamics in mouse models human cohorts, especially focusing on role repeated Omicron stimulation. Our...
This study aimed to explore the cumulative effects and expression patterns of electroacupuncture (EA) on irisin secretion, observe EA recovery neurobehavioral function vascular remodeling after cerebral ischemia, elucidate mechanism by which promotes regulating expression. A rat model left middle artery occlusion (MCAO) was prepared, performed. Tissue distribution were determined immunofluorescence, enzyme-linked immunosorbent assay (ELISA), Western blotting. Type III fibronectin domain...
This study aims to investigate whether Hounsfield unit (HU) value is correlated with intervertebral disc (IVD) degeneration (IVDD) by comparing premenopausal menopausal women patients. A total of 101 female patients who underwent treatment in our hospital between February 2022 and 2023 were retrospectively reviewed included this study. All divided into either the group or group, according age menopause status. The changes height index (DHI) on X-ray, computed tomography (CT), area nucleus...
We have reviewed 10 patients treated for anterior tarsal tunnel syndrome produced by compression of the deep peroneal nerve or its branches, and we studied anatomy in 25 adult feet. The causes onset included contusion dorsum foot, tight shoe laces, talonavicular osteophytosis, ganglion, pes cavus. clinical signs were often diagnostic but electromyography was helpful. Operative decompression nine feet eight gave successful results at 1.5 to 4 years follow-up.
Is pinopode measurement of any prognostic value?Pinopode expression was significantly associated with the occurrence pregnancy after frozen embryo transfer.Pinopodes are expressed in endometrium during implantation period. Pinopode has been proposed as a marker endometrial receptivity.A prospective cohort study conducted at Center Reproductive Medicine, Sir Run Shaw Hospital, between 2014 and 2016, recruiting 172 women infertility undergoing transfer following IVF treatment. Among...
Idiopathic inflammatory myopathies (IIM) are a class of autoimmune diseases with high heterogeneity that can be divided into different subtypes based on clinical manifestations and myositis-specific autoantibodies (MSAs). However, even in each IIM subtype, the symptoms prognoses patients very different. Thus, identification more potential biomarkers associated classification, symptoms, prognosis is urgently needed.
Patients with spinal cord injury (SCI) often suffer from varying degrees of neuropathic pain.Non-invasive repetitive transcranial magnetic stimulation (TMS) has been shown to improve pain, while the appropriate intervention strategies TMS treatment and how affects brain function after SCI were not entirely clear. To investigate effects mechanisms on pain SCI, high-frequency primary motor cortex (M1) mice was performed response evaluated through an electronic Von-Frey device cold/hot plates....