A5080666843- Cancer Immunotherapy and Biomarkers
- Cytokine Signaling Pathways and Interactions
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Job Satisfaction and Organizational Behavior
- Vascular Procedures and Complications
- Cancer Cells and Metastasis
- Gender Diversity and Inequality
- Central Venous Catheters and Hemodialysis
- Cancer Genomics and Diagnostics
- Immune Cell Function and Interaction
- COVID-19 Impact on Reproduction
- Rhetoric and Communication Studies
- Urologic and reproductive health conditions
- Maternal and Perinatal Health Interventions
- Stress Responses and Cortisol
- Emergency and Acute Care Studies
- Enhanced Recovery After Surgery
- Global Cancer Incidence and Screening
- Digital Economy and Work Transformation
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Heterotopic Ossification and Related Conditions
- Experimental Behavioral Economics Studies
- Parasitic infections in humans and animals
- CAR-T cell therapy research
Dartmouth–Hitchcock Medical Center
2025
Queen Elizabeth II Jubilee Hospital
2024
University of California, Irvine
2023
Lehigh Valley Health Network
2022-2023
University of South Florida
2022-2023
Lehigh Valley Hospital-Pocono
2023
New York University
2021
City of Hope
2016
Beckman Research Institute
2016
City Of Hope National Medical Center
2015
Prostate cancer (PCa) disproportionately affects African American men, but research evaluating the extent of racial and ethnic disparities across PCa continuum in equal-access settings remains limited at national level. The US Department Veterans Affairs (VA) Hospital Administration health care system offers a setting relatively equal access to which assess self-identified (or Black) veterans White veterans.
Overexpression of P2X7 receptors correlates with tumor growth and metastasis. Yet, release ATP is associated immunogenic cancer cell death as well inflammatory responses caused by necrotic at sites trauma or ischemia-reperfusion injury. Using an FDA-approved anti-parasitic agent Ivermectin a prototype to allosterically modulate P2X4 receptors, we can switch the balance between dual pro-survival cytotoxic functions purinergic signaling in breast cells. This mediated through augmented opening...
Abstract IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts directly on cancer cells to promote their survival proliferation. Elevated serum levels negatively correlate of patients, generally attributed the direct effects cells. How modulates host immune response in patients unclear. Here, we show signaling peripheral blood T impaired breast associated blunted Th17 differentiation. The mechanism identified involved downregulation gp130 IL6Rα was...
Introduction: First-insertion success rates for peripheral vascular access devices (PVADs) in patients with difficult venous (DIVA) are low, which negatively affects staff workload, patient experience, and organizational cost. There is mixed evidence regarding the impact of a device retractable coiled tip guidewire (GW; AccuCath™, BD) on first-insertion rate. The aim this study to investigate whether use long GW-PVADs, compared standard PVADs, reduces risk first-time insertion failure,...
Opioids are routinely prescribed to patients postoperatively after cesarean delivery. With rates of deliveries increasing globally and the opioid epidemic continuing have deleterious effects, finding methods achieve effective pain control without opioids is importance. The ERAS (Enhanced Recovery After Surgery) protocol applied following delivery engages multimodal perioperative management techniques encourage early recovery. In obstetrical surgery setting, these interventions include...
The etonogestrel implant is generally considered an effective, three-year, long-acting reversible contraceptive device. Previous research, such as the landmark CHOICE study, has reported a one-year continuation rate of 72% to 84%, however, in real-world setting these rates may be significantly lower.To study and factors associated with early discontinuation specific clinical setting.Single-center, retrospective cohort patients who received between January 1, 2015, December 31, 2017, at...
We develop and test a more comprehensive theory of the sources effects workplace favoritism by drawing on large, agency-wide sample U.S. Federal Aviation Administration employees. report how members various underrepresented groups differ in their perceptions variety favoritism. find that friendship are an important source perception for all show negatively associated with employee trust organizations coworkers, commitment to organizations, willingness speak up, pay satisfaction,...
Abstract Background A quarter of patients who present to emergency departments (EDs) have difficult intravenous access (DIVA), making it challenging for clinicians successfully place a peripheral catheter (PIVC). Some literature suggests that guidewire PIVC improves first‐insertion success rate. Aim The aim was determine the clinical and cost‐effectiveness novel long (5.8 cm) with retractable coiled (GW‐PIVC) DIVA, compared standard care PIVCs. Methods pragmatic randomized controlled trial...
<div>Abstract<p>IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts directly on cancer cells to promote their survival proliferation. Elevated serum IL6 levels negatively correlate of patients, generally attributed the direct effects cells. How modulates host immune response in patients unclear. Here, we show signaling peripheral blood T impaired breast associated blunted Th17 differentiation. The mechanism identified involved downregulation...
<div>Abstract<p>IL6 is a pleiotropic cytokine with both pro- and anti-inflammatory properties, which acts directly on cancer cells to promote their survival proliferation. Elevated serum IL6 levels negatively correlate of patients, generally attributed the direct effects cells. How modulates host immune response in patients unclear. Here, we show signaling peripheral blood T impaired breast associated blunted Th17 differentiation. The mechanism identified involved downregulation...
Bi-femoral axillary bypass graft placement is a well-known and typically safe procedure. It generally indicated for patients with advanced peripheral vascular disease, aortoiliac occlusive or infectious artery disease. In rare cases, the can be fractured dislodged after placement, though most often, this occurs almost exclusively at anastomosis site, secondary to blunt trauma. Using ultrasonic imaging reliable method of detecting these fractures. We present case bi-femoral fracture in...
An Interview with ALEX is a 12-minute interactive experience that engages the participant in job interview ALEX, powerful artificial intelligence HR employed by speculative tech giant called "Open Mind Corporation." Through science-fiction lens, reveals how (AI) and gamification of work can be used as subtle tools control interest those power.