A5058605437- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Animal Behavior and Welfare Studies
- Effects of Environmental Stressors on Livestock
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- GABA and Rice Research
- Demographic Trends and Gender Preferences
- Cancer Genomics and Diagnostics
- Plant Reproductive Biology
- Molecular Biology Techniques and Applications
- Nuts composition and effects
- Rice Cultivation and Yield Improvement
- Horticultural and Viticultural Research
- Nutrition, Genetics, and Disease
- Gene expression and cancer classification
- Genetic diversity and population structure
- Ruminant Nutrition and Digestive Physiology
University of Buenos Aires
2016-2024
Element Six (Ireland)
2024
Génétique Physiologie et Systèmes d'Elevage
2020-2022
Nucleus (Norway)
2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2021
Consejo Nacional de Investigaciones Científicas y Técnicas
2016
Metafounders are pseudo-individuals that encapsulate genetic heterozygosity and relationships within across base pedigree populations, i.e. ancestral populations. This work addresses the estimation usefulness of metafounder in single-step genomic best linear unbiased prediction (ssGBLUP). We show relationship parameters proportional to standardized covariances allelic frequencies such as $$F_{\text{st}}$$ fixation indexes. These can be estimated from marker genotypes related recent...
Feed consumption and feeding patterns influence the individual feed efficiency in group-housed livestock species. Using meal as unit of behaviour, main objectives this research were to identify behaviour (FB) traits that may indicate an individual's rank within social hierarchy or its level dominance among pen mates assess relationship between growth with identified traits, well those describing patterns. Data from 5516 pigs during fattening period used. Pens equipped automatic concentrate...
The single-step covariance matrix H combines the pedigree-based relationship $${\mathbf {A}}$$ with more accurate information on realized relatedness of genotyped individuals represented by genomic {G}}$$ . In particular, to improve convergence behavior iterative approaches and reduce inflation, two weights $$\tau$$ $$\omega$$ have been introduced in definition {H}}^{-1}$$ , which blend inverse a part Since this blending is based equation describing its impact structure {H}}$$ not obvious....
Abstract Background Resilient animals can remain productive under different environmental conditions. Rearing in increasingly heterogeneous conditions increases the need of selecting resilient animals. Detection challenges that affect an entire population provide a unique opportunity to select are more these events. The objective this study was two-fold: (1) present simple and practical data-driven approach estimate probability that, at given date, unrecorded challenge occurred; (2) evaluate...
Abstract Allele substitution effects at quantitative trait loci (QTL) are part of the basis genetics theory and applications such as association analysis genomic prediction. In presence nonadditive functional gene action, not constant across populations. We develop an original approach to model difference in populations a first order Taylor series expansion from “focal” population. This involves allele frequencies second-order statistical (additive by additive dominance). The change is...
Estimates of dominance variance for growth traits in beef cattle based on pedigree data vary considerably across studies, and the proportion genetic explained by deviations remains largely unknown. The potential benefits including nonadditive effects genomic model combined with increasing availability large sets have recently renewed interest evaluation models. information enables computation covariance matrices dominant relationships among animals, similar to additive relationships, a more...
Genomic relationships based on markers capture the actual instead of expected (based pedigree) proportion genome shared identical by descent (IBD). Several methods exist to estimate genomic relationships. In this research, we compare four such that were tested looking at empirical distribution estimated across 6704 pairs half-sibs from a cross-bred pig population. The first method multiple marker linkage analysis displayed mean and standard deviation (SD) in close agreement with ones was...
Inbreeding depression reduces the mean phenotypic value of important traits in livestock populations. The goal this work was to estimate level inbreeding and for growth reproductive Argentinean Brangus cattle, order obtain a diagnosis monitor breed management. Data comprised 359,257 (from which 1,990 were genotyped 40,678 single nucleotide polymorphisms [SNPs]) animals with records at least one three traits: birth weight (BW), weaning (WW), finishing (FW). For scrotal circumference (SC),...
Genome inheritance is by segments of DNA rather than independent loci. We introduce the ancestral regression (AR) as a recursive system simultaneous equations, with grandparental path coefficients novel parameters. The information given pedigree in AR complementary that provided dense set genomic markers, such resulting linear function BV uncorrelated to average parental absence inbreeding. then connected segmental causal multivariate Gaussian density for BV. covariance structure (Σ)...
Spanish Latxa and French Manech are dairy sheep breeds that split into Blond (Latxa Cara Rubia, LCR; Tête Rousse, MTR) Black Negra of Navarre, LCN; Noire, MTN) strains. Exchange genetic material (artificial insemination doses) is becoming more frequent across these breeds, within color, to boost both genomic precision using a larger reference population progress selection base. This exchange leads some rams having descendance countries. However, additional gains can only be achieved if the...
In pig breeding, environmental challenges can affect the welfare and productivity of animals. Resilient animals have capacity to be minimally affected by these challenges. Understanding genetic basis sensitivity is crucial for selecting more resilient animals, thereby enhancing productivity. The aims this study were 1) estimate probability occurrence an unrecorded challenge on a given day using daily feed intake (DFI) data 2) evaluate determinism in three lines bred real selection...
ABSTRACT Allele substitution effects at quantitative trait loci (QTL) are part of the basis genetics theory and applications such as association analysis genomic prediction. In presence non-additive functional gene action, not constant across populations. We develop an original approach to model difference in populations a first order Taylor series expansion from “focal” population. This involves allele frequencies second-order statistical (additive by additive dominance). The change is...
ABSTRACT BACKGROUND Metafounders are pseudo-individuals that condense the genetic heterozygosity and relationships within across base pedigree populations, i.e. ancestral populations. This work addresses estimation usefulness of metafounder in Single Step GBLUP. RESULTS We show relationship parameters proportional to standardized covariances allelic frequencies like Fst fixation indexes. These can be estimated from marker genotypes related recent individuals, pedigree. Simple methods for...
Abstract One of the limitations implementing animal breeding programs in small-scale or extensive production systems is lack records and genealogical records. In this context, molecular markers could help to gain information for program. This study addresses inclusion data into traditional genetic evaluation models as a random effect by pedigree reconstruction fixed Bayesian clustering. The methods were tested lactation curve traits 14 dairy goat herds with incomplete phenotypic information....