- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Vascular Procedures and Complications
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Central Venous Catheters and Hemodialysis
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Orthopaedic implants and arthroplasty
- Aortic Disease and Treatment Approaches
Leipzig Heart Institute
2021-2025
Deutsches Herzzentrum der Charité
2022
Leipzig University
2022
Transcatheter aortic valve replacement is an established treatment option for patients with severe symptomatic stenosis and most commonly performed through the transfemoral access route. Percutaneous site closure can be achieved using dedicated plug-based or suture-based vascular device (VCD) strategies, but randomized comparative studies are scarce.The CHOICE-CLOSURE trial (Randomized Comparison of Catheter-based Strategies Interventional Access Site Closure during Transfemoral Aortic Valve...
Abstract Background Heart failure with preserved ejection fraction (HFpEF) has recently been proposed as important comorbid condition in patients undergoing transcatheter aortic valve replacement (TAVR) for stenosis (AS). The H2FPEF-score and the HFA-PEFF-score are used to diagnose HFpEF, but their use might be hampered by lack of specificity TAVR-populations. Left atrial reservoir strain (LARS) emerged a powerful predictor outcomes AS irrespective (EF). Purpose To assess prognostic value...
A study evaluating the efficacy and safety of using MANTA plug-based vascular closure device as a bailout technique in 66 patients experiencing failed suture-based during transfemoral transcatheter aortic valve implantation procedures.
Abstract Aims Patients with diastolic dysfunction (DD) experience worse outcomes after transcatheter aortic valve replacement (TAVR). We investigated the prognostic value and clinical utility of left atrial reservoir strain (LARS) in patients undergoing TAVR for stenosis (AS). Methods results All consecutive between January 2018 December were included if discharge echocardiography follow-up available. LARS was derived from 2D-speckle-tracking. grouped into three tertiles according to LARS....
BackgroundThe location and severity of vascular calcification may influence closure device success in transfemoral transcatheter aortic valve implantation. The aim this study was to analyze effects access-site on bleeding outcomes post-transcatheter implantation.MethodsThe Randomized Comparison CatHeter-based Strategies fOr Interventional ACcess SitE CLOSURE during Transfemoral Transcatheter Aortic Valve Implantation (CHOICE-CLOSURE) trial assigned 516 patients access site using a pure...
Die Fortschritte der interventionellen Kardiologie und Angiologie führen zu einer wachsenden Zahl an Prozeduren, die einen großlumigen Gefäßzugang (≥ 9 French [Fr]) benötigen. Der postprozedurale Gefäßverschluss ist dabei von erheblicher Bedeutung, da Zugangskomplikationen mit einem relevanten Anstieg Mortalität Morbidität verbunden sind 1. In diesem Beitrag werden verschiedene Gefäßverschlusssysteme vorgestellt deren Umgang beschrieben.
Zusammenfassung Bei einer asymptomatischen hochgradigen Aortenklappenstenose (AS) mit normaler linksventrikulärer Funktion sollte eine „Watchful-Waiting“-Strategie verfolgt werden. Asymptomatische Patienten Risikofaktoren, wie sehr schwere AS, kalzifizierter AS oder 3-fach erhöhtem proBNP-Level, können bei niedrigem operativem Risiko Intervention erhalten. Erste randomisierte Studien weisen auf einen Vorteil des frühzeitigen Aortenklappenersatzes OP-Risiko hin. Für Aortenklappeninsuffizienz...