A5091235771- COVID-19 Clinical Research Studies
- COVID-19 Impact on Reproduction
- COVID-19 Pandemic Impacts
- COVID-19 and healthcare impacts
- Global Maternal and Child Health
- Hepatitis C virus research
- COVID-19 epidemiological studies
- HIV/AIDS drug development and treatment
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Nutritional Studies and Diet
- HIV-related health complications and treatments
- Pregnancy and preeclampsia studies
- Blood Pressure and Hypertension Studies
- Health Promotion and Cardiovascular Prevention
- COVID-19 impact on air quality
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Sepsis Diagnosis and Treatment
- Maternal Mental Health During Pregnancy and Postpartum
Beth Israel Deaconess Medical Center
2024-2025
Harvard University
2025
Hadassah Medical Center
2024
Icahn School of Medicine at Mount Sinai
2020-2022
Elmhurst Hospital Center
2021
Rutgers New Jersey Medical School
2017-2020
Rutgers, The State University of New Jersey
2017-2020
Previous viral pandemics have shown that secondary bacterial infections result in higher morbidity and mortality, with Staphylococcus aureus being the primary causative pathogen. The impact of S. bacteremia on mortality patients infected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unknown.This was a retrospective observational case series disease 2019 (COVID-19) who developed across New York City hospitals. end point to describe 14-day 30-day hospital rates COVID-19...
Abstract Background Households are a major setting for SARS-CoV-2 infections, but there remains lack of knowledge regarding the dynamics viral transmission, particularly in pre-existing immunity and evolving variants.Table 1.SARS-CoV-2 Secondary Attack Rates (SAR) Methods We conducted prospective, case-ascertained household transmission study greater Boston area March-July 2022. Anterior nasal swabs, along with clinical demographic data, were collected 14 days. Nasal swabs tested by PCR....
Simple clinical markers may predict favorable outcomes in pediatric HIV treatment and cure trials. We report findings for biomarker combinations evaluated during the broadly neutralizing antibodies (bNAbs)-only step of Tatelo Study Botswana. Twenty-five children who were on ART since birth received up to 24 weeks bNAb-only (VRC01LS+10-1074). Suppression was defined as maintaining RNA<400 copies/mL. qualitative DNA RNA performed every 1-2 enzyme immunosorbent assay (EIA) 4-8 weeks. The median...
Background The global pandemic caused by severe acute respiratory syndrome coronavirus 2 resulted in a large burden of critically ill patients, population with an increased risk both developing and dying from secondary infections. We investigated the clinical characteristics, factors, outcomes associated bloodstream infections (BSIs) among those admitted to intensive care unit (ICU) for disease 2019 (COVID-19) during peak first surge New York City, before standardization treatment regimens...
OBJECTIVE: To evaluate the combined association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and human immunodeficiency virus (HIV) infection on adverse birth outcomes in an HIV-endemic region. METHODS: The Tsepamo Study abstracts data from antenatal obstetric records government maternity wards across Botswana. We assessed maternal mortality for all singleton pregnancies September 2020 to mid-November 2021 at 13 sites among individuals with documented SARS-CoV-2 screening...
Reports conflict on how HIV infection influences the clinical course of COVID-19. The New York City (NYC) public hospital system provides care for over 14,000 people with HIV, was central in responding to COVID-19 pandemic, and is therefore a unique position evaluate intersection these concurrent infections. Retrospective chart review patients presenting NYC Health Hospitals (NYC H+H) diagnosed from March 1, 2020, through April 28, compared living (PLWH) propensity-matched (PM) control group...
Abstract Background Households are a major setting for SARS-CoV-2 infections, but there remains lack of knowledge regarding the dynamics viral transmission, particularly in widespread pre-existing immunity and evolving variants. Methods We conducted prospective, case-ascertained household transmission study greater Boston area March-July 2022. Anterior nasal swabs, along with clinical demographic data, were collected 14 days. Nasal swabs tested by PCR. Whole genome sequencing was performed...
SARS-CoV-2 infection during pregnancy was associated with maternal mortality and adverse birth outcomes in the pre-Omicron era, including a stillbirth rate of 5.6% Botswana. We re-evaluated these Tsepamo Study Omicron era. assessed for all singleton pregnancies from mid-November 2021 (the start era) to mid-August 2022 at nine sites, among individuals documented screening PCR or antigen tests known HIV status. Of 9,705 women routinely screened delivery (64% deliveries sites), 373 (3.8%)...
Abstract Background Households are a major setting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, but there remains lack of knowledge regarding the dynamics viral transmission, particularly in preexisting SARS-CoV-2 immunity and evolving variants. Methods We conducted prospective, case-ascertained household transmission study greater Boston area March–July 2022. Anterior nasal swabs, along with clinical demographic data, were collected 14 days. Nasal swabs...
Treatment of hepatitis C virus (HCV) infection for patients with human immunodeficiency (HIV) has improved direct acting antivirals. However, outcomes among Black persons treated ledipasvir/sofosbuvir (LDV/SOF) may be inferior to non-Blacks. We assessed responses LDV/SOF in a cohort HIV/HCV coinfected persons.Retrospective chart reviews were conducted Black, genotype 1 (GT1), at 3 hospitals Newark, NJ between January 2014 and July 2016. Data collected included demographics, HCV treatment...
Treatment of Hepatitis C virus (HCV) infection for patients with Human Immunodeficiency Virus (HIV) has improved direct acting antivirals (DAAs). However, outcomes among Black persons treated ledipasvir/sofosbuvir (LDV/SOF) may be inferior to non-Blacks. We assessed responses LDV/SOF in a cohort HIV/HCV co-infected Newark, New Jersey. Retrospective chart reviews were conducted Black, genotype 1 (GT1), at three hospitals Jersey between January 2014 and July 2016. Data collected included...