A5068088727- Foot and Ankle Surgery
- Bone fractures and treatments
- Connective tissue disorders research
- Lower Extremity Biomechanics and Pathologies
- Neurogenetic and Muscular Disorders Research
- Congenital limb and hand anomalies
- Hip disorders and treatments
- Tendon Structure and Treatment
- Scoliosis diagnosis and treatment
- Orthopaedic implants and arthroplasty
- Orthopedic Surgery and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Hip and Femur Fractures
- Cerebral Palsy and Movement Disorders
- Elbow and Forearm Trauma Treatment
- Metabolism and Genetic Disorders
- Orthopedic Infections and Treatments
- Spinal Dysraphism and Malformations
- Botulinum Toxin and Related Neurological Disorders
- Pelvic and Acetabular Injuries
- Bone health and treatments
- Total Knee Arthroplasty Outcomes
- Shoulder Injury and Treatment
- Bone and Joint Diseases
- Musculoskeletal synovial abnormalities and treatments
Clinical Orthopaedics and Related Research
2016-2023
St. Mary's Medical Center
2023
United States Bone and Joint Initiative
2023
St. Louis Children's Hospital
2010-2022
Shriners Hospitals for Children - St. Louis
2008-2020
Washington University in St. Louis
2011-2020
Neurological Surgery
2009-2020
Pitney Bowes (France)
2020
LuK Lamellen und Kupplungsbau (Germany)
2020
GTx (United States)
2011-2019
The nonoperative technique for the treatment of idiopathic congenital talipes equinovarus (clubfoot) described by Ponseti is a popular method, but it requires two to four years orthotic management. purpose this study was examine patient characteristics and demographic factors related family that are predictive recurrent foot deformities in patients treated with method.The cases fifty-one consecutive infants eighty-six clubfeet use method were examined retrospectively. at time presentation,...
Background: Although long-term follow-up studies have shown favorable results, in terms of foot function, after treatment idiopathic clubfoot with serial manipulations and casts, we know no patients whom was treated an extensive surgical soft-tissue release. Methods: Forty-five (seventy-three feet) either a posterior release plantar fasciotomy (eight patients) or combined posterior, medial, lateral (thirty-seven were followed for mean thirty years. Patients evaluated detailed examination the...
Treatment with the Ponseti method corrects congenital idiopathic clubfeet in majority of patients. However, some feet do not respond to standard treatment protocol. We describe characteristics and results these complex clubfeet. identified 50 patients (75 clubfeet) from 762 consecutive treated at five institutions. Clinically, were defined as having rigid equinus, severe plantar flexion all metatarsals, a deep crease above heel, transverse sole foot, short hyperextended first toe. The...
Limited data exist about complications of titanium elastic nails (TNs) for femur fracture management in pediatric patients. Thirty-nine patients with 43 femoral shaft fractures were identified whose average age was 6.0 years. There 21 (1 intraoperative, 20 postoperative) (49%). two major postoperative complications: one septic arthritis after nail removal and hypertrophic nonunion. Minor pain at the 13 extremities, erosion through skin 4, delayed union. an association between prominence TNs...
In Brief Study Design. A retrospective review of adolescent idiopathic scoliosis (AIS) patients with major thoracic-compensatory lumbar C modifier curves treated a selective posterior fusion using an all-hook construct versus pedicle screw construct. Objectives. To compare the clinical and radiographic results thoracic hooks screws in AIS curves. Summary Background Data. Although spontaneous curve correction often occurs following spinal fusion, there are few reports that focus on presence...
Adolescent idiopathic scoliosis (AIS) is an unexplained and common spinal deformity seen in otherwise healthy children. Its pathophysiology poorly understood despite intensive investigation. Although genetic underpinnings are clear, replicated susceptibility loci that could provide insight into etiology have not been forthcoming. To address these issues, we performed genome-wide association studies (GWAS) of ∼327 000 single nucleotide polymorphisms (SNPs) 419 AIS families. We found strongest...
In Brief Study Design. A retrospective review of patients with adolescent idiopathic scoliosis (AIS), curves more than 90° treated either a combined anterior/posterior spinal fusion or posterior alone. Objectives. To assess the results for AIS >90° and determine whether use posterior-only approach an all-pedicle screw construct can decrease need anterior release surgery. Summary Background Data. Treatment often consists to improve coronal correction rate. However, pedicle screws has allowed...
Supracondylar distal humerus fractures are one of the most common skeletal injuries in children. The current treatment choice North America is closed reduction and percutaneous pin fixation. Often surgeons leave pins exposed beneath a cast but outside skin. Great variation exists with respect to preoperative skin preparation, perioperative antibiotic administration. Few data exist regarding rate infection other complications. purpose this study review large series children evaluate...
Adolescent idiopathic scoliosis (AIS) causes spinal deformity in 3% of children. Despite a strong genetic basis, few genes have been associated with AIS and the pathogenesis remains poorly understood. In genome-wide rare variant burden analysis using exome sequence data, we identified fibrillin-1 (FBN1) as most significantly gene AIS. Based on these results, FBN1 related gene, fibrillin-2 (FBN2), were sequenced total 852 cases 669 controls. individuals European ancestry, variants FBN2...
Background: Although long-term follow-up studies have shown favorable results, in terms of foot function, after treatment idiopathic clubfoot with serial manipulations and casts, we know no patients whom was treated an extensive surgical soft-tissue release. Methods: Forty-five (seventy-three feet) either a posterior release plantar fasciotomy (eight patients) or combined posterior, medial, lateral (thirty-seven were followed for mean thirty years. Patients evaluated detailed examination the...
Background: Although reports in the literature have demonstrated an approximately 20% prevalence of neural axis abnormalities patients with juvenile idiopathic scoliosis who a curve >20°, infantile is not well documented. In two previous studies involving total only ten scoliosis, five were noted to abnormality on magnetic resonance images. Methods: The records forty-six consecutive seen between 1992 and 2000 at three spinal deformity clinics retrospectively reviewed. inclusion criteria...
Background: Clubfoot occurs in approximately one 1000 live births and is of the most common congenital birth defects. Although there have been several reports successful treatment idiopathic clubfoot with Ponseti method, use this method for other forms has not reported. The purpose present study was to evaluate early results when used associated distal arthrogryposis. Methods: Twelve consecutive infants (twenty-four feet) deformity arthrogryposis were managed retrospectively reviewed at a...
The treatment of idiopathic congenital vertical talus has traditionally consisted manipulation and application casts followed by extensive soft-tissue releases. However, this is often severe stiffness the foot other complications. purpose study was to evaluate a new method cast immobilization, based on principles used Ponseti for clubfoot deformity, pinning talonavicular joint percutaneous tenotomy Achilles tendon in patients with talus.The cases eleven consecutive who had total nineteen...
A retrospective review of 60 diaphyseal tibia fractures (31 closed and 29 open fractures) treated with flexible intramedullary fixation was conducted. All charts radiographs were reviewed. Children ranged in age from 5.1 to 17 years. Fifty patients 51 followed up until union comprised the study group. The mean follow-up period for these 50 79 weeks. Forty-five achieved bony within 18 weeks (mean, 8 weeks). Five (11%) had delayed healing (3 unions that ultimately healed casting or...
Although congenital talipes equinovarus (CTEV) is often idiopathic, additional birth defects occur in some patients that may have an impact on the treatment of this disorder. The purpose study was to determine prevalence associated malformations, chromosomal abnormalities, or known genetic syndromes, and compare outcomes children with idiopathic CTEV non‐idiopathic CTEV. Of 357 evaluated, 273 (76%) had (179 males, 94 females; mean age 2y 1mo [SD 1y 2mo], range 0–18y) 84 (24%) CETV (51 33 5mo...
The treatment of femoral shaft fractures in older children and adolescents using rigid intramedullary (IM) nail fixation offers the advantages decreased soft tissue stripping, low incidence malalignment, leg length discrepancy, early ambulation, hospital stay. Recent reports have described development osteonecrosis head after IM nailing through piriformis fossa tip greater trochanter. Others noted secondary proximal valgus neck narrowing antegrade nailing. Using lateral aspect \trochanter as...
Spatio-temporal expression of sonic hedgehog (SHH) is driven by a regulatory element (ZRS) that lies 1 Mb upstream from SHH. Point mutations within the highly conserved ZRS have been described in hemimelic extra toes mouse and four families with preaxial polydactyly [Lettice et al., 2003]. Four North American Caucasian were identified autosomal dominant triphalangeal thumb. DNA 20 affected 36 unaffected family members was evaluated sequence analysis 774-bp contained LMBR1 intron 5. Mutations...
This was a 23-year retrospective study of 3436 consecutive pediatric orthopedic spinal surgery patients between 1995 and 2008.To demonstrate the effectiveness multimodality electrophysiologic monitoring in reducing incidence iatrogenic neurologic deficit population.The elective nature many procedures continues to drive need for minimizing risk each individual patient. Electrophysiologic has been proposed as an effective means decreasing permanent injury this population.A total monitored at...