<title>Abstract</title> <bold>Objective</bold> This study sought to investigate the prognostic impact of a novel ventricular-vascular coupling index, arterial velocity pulse index (AVI) left ventricular global circumferential strain (GCS) ratio (AVI/GCS) in patients with COVID-19. <bold>Methods</bold><italic> </italic>217 who were diagnosed COVID-19 retrospectively reviewed over 2- month period, and stratified into two groups (mild moderate/severe). The traditional indexes (effective...

Arterial wall elasticity including the circumferential and longitudinal modulus is a measure of sub-clinical cardiovascular disease; increased in acute ischemic stroke (AIS). There are still no reports non-invasive measurement elastic arterial its prospect clinical application. In this study, was assessed using real-time shear wave elastography patients with AIS. The technique's feasibility related factors were studied initially.In study 179 AIS 168 age- sex-matched controls examined. pulse...

Abstract Aims The COVID‐19 infection has been described as affecting myocardial injury. However, the relation between left ventricular global longitudinal strain (GLS), circumferential (GCS) and radial (GRS), disease severity all‐cause mortality in is unclear. Methods Results study consisted of 220 patients with COVID‐19, including 127 (57.5%) mild, 43 (19.5%) moderate 50 (22.7%) severe/critical conditions. Myocardial dysfunction was analysed by GLS, GCS GRS using two‐dimensional...

Inflammatory activity plays a central role in the development of carotid rupture-vulnerable atherosclerotic plaques, which is one major contributors to acute ischemic stroke. Our objective was characterize intraplaque neovascularizations (INP) using contrast-enhanced ultrasound (CEUS) and evaluate plaque burden through exploring relationship between INP cell count peripheral leukocytes. Sixty-two patients with large artery atherosclerosis (LAA) were enrolled this study. CEUS performed...

Abstract Carotid webs may cause a frequent recurrent ischemic stroke. Based on the database of patients with transient attack (TIA), demographics, clinical, and imaging characteristics were compared between carotid web without it. Twelve younger more in females than those Both clinical features determined that prone to TIA due pooling blood stagnation consequent thrombosis. Ultrasonography has big potential for assessment risk stratification web.

Aims: This study’s aim is to present the specific ultrasonography (US) findings of a series urachus anomalies. Material and methods: Seven patients with suspected urachal anomalies underwent US scanning initially prior surgery features images were reviewed respectively. The clinical data pathologic results collected also. Results: successfully diagnosed in 5 (5/7, 71.4%) failed diagnose 2 (2/7, 28.6%). Patent showed tubule between umbilicus bladder; sinus was blind focal dilatation at...

Aim: The clinical value of glucagon‐like peptide‐1 (GLP‐1) is restricted because its short half‐life. To overcome this limitation, a new polymer GLP‐1 was developed by prodrug strategy, termed Poly‐GLP‐1, and pharmacological properties were investigated. Methods: in vitro release kinetics from Poly‐GLP‐1 analysed Western blot. Plasma levels following single administration determined enzyme‐linked immunosorbent assay. effects evaluated using isolated pancreatic islets. acute on glycaemic...

Abstract Background Arterial remodeling is thought to reflect the adaptation of vessel wall mechanical and hemodynamic stimuli contributes progression cardiovascular cerebrovascular diseases. Tensile stress (TS) one properties artery wall. The purpose this study was investigate tensile change carotid with varying viscoelasticity in healthy subjects within two groups different ages. Methods Forty-five were recruited randomly assigned into group at age above 50 years below years. arteries...

Neovascularization in plaque is the main driving factor for formation of vulnerable plaque. It an effective strategy to alleviate atherosclerosis by intervening neovascularization. Herein, we constructed a cRGD peptide (cyclo(Arg–Gly–Asp–d-Phe–Cys))-modified nanodelivery systems (RNPs) targeted delivery antiangiogenesis drug pigment epithelium-derived (PEDF), which known as strongest endogenous angiogenesis inhibitor. PEDF RNPs have suitable size and good stability, conducive passive target...

In ultrasonic flow metering, the inner pipe wall will be distorted by transducer’s installation, and velocity profile of meter different from that in a long straight located front or behind section. Changes finally influence measurement accuracy. This paper shows multi-path with its transducers installed at positions. Our purpose is to find best transducer installation position study path numbers diameters on accuracy position. With computational fluid dynamics (CFD) analysis, profiles are...

Background: To explore the value of a novel ventricular-vascular coupling index (VVI) system in relation to age, gender and body mass (BMI). Methods: A total 239 volunteers with single-center cross-sectional health screening were enrolled study. Subjects divided according age (young [18–44 years], middle-age [45–59 old [60–80 years]), (male, female), BMI (overweight/obese [BMI ≥24], control <24]). The left ventricle end-diastolic volume (LVEDV) end-systolic (LVESV) provided ventricular...

Summary 1 The aim of this study was to investigate the co‐localization histamine and dopamine‐ β ‐hydroxylase in superior cervical ganglion guinea‐pig release from cardiac sympathetic terminals isolated atrium. 2 Histidine decarboxylase (a histamine‐synthesizing enzyme) mRNA signals were detected neurones by situ hybridization. results double‐labelled immunofluorescence further confirmed large principle neurons small intensely fluorescent cells ganglion. immunoreactivities both significantly...

This study was aimed to evaluate the feasibility and accuracy of real-time three-dimensional echocardiography (RT-3DE) measurement left atrial (LA) volume function in comparison with two-dimensional (2DE) measurements fibrillation (AF) patients.A total 50 pairs AF patients healthy controls were enrolled this study. Indexed LA end-diastole (ILAEDV) indexed end-systolic (ILAESV), as well indices such segmental ejection fraction (LAEF), assessed using 2DE Simpson's method RT-3DE method.The...

Renal transplantation can significantly improve the quality of life patients with end stage renal disease (ESRD) who would otherwise require dialysis. transplant (RT) recipients have higher risks cardiovascular compared general population. The carotid intima-media thickness (CIMT) and pulse wave velocity (PWV) been used as important predicting factor vascular arteriosclerosis. Therefore, this study was to investigate improvement in recipients. Thirty-one chronic kidney being treated...

Carotid arterial dissection is an important cause of stroke in young and middle-aged patients.Ultrasound (and particularly contrast enhanced ultrasonography) approach patients with sudden onset combined renal failure who are not suitable for angiography.In this report we describe the ultrasound features carotid discuss its utility.

Abstract Intravenous leiomyomatosis (IVL) with intracardiac extension is a rare condition, which the benign tumor invades into right heart through inferior vena cava. We described findings of ultrasonography in eight patients this disease. Transthoracic echocardiography (TTE) can reveal lesion burden and associated compromise. Contrast‐enhanced (CEUS) trace origin extension. Therefore, combining TTE CEUS used to better characterize complex plays crucial role guidance surgical decision.

This study evaluates carotid vulnerable plaques using contrast-enhanced ultrasound (CEUS) and explores the relationship between leukocytes.Sixty-two symptomatic 54 asymptomatic patients underwent CEUS. The images were analyzed time-intensity fitting curves, peak (PTIC), mean (MTIC), (PFC), sharpness (SFC), area under curve (AUCFC) obtained. relations CEUS parameters leukocytes analyzed.In group, total neutrophils higher, while lymphocyte was decreased; PTIC, MTIC, PFC, SFC, AUCFC...

Abstract Congenital left main coronary atresia (LMCA) is a rare anomaly associated with myocardial ischemia and sudden death. Echocardiography an important tool for diagnosis of LMCA. The results echocardiography relevant clinical signs were retrospectively analyzed in 3 children Echocardiographic examination showed the LMCA: sinus no opening artery (LCA), retrograded blood flow LCA, abound ventricular wall, mild widen RCA.

Background: Arterial pressure volume index (API) offers a non-invasive measurement of brachial artery residual stress. This study investigated API distribution characteristics and correlations with cardiovascular disease risk (CVD) factors in large Chinese population sample. Methods: cross-sectional surveyed total 7620 participants. We analyzed the relationships between influencing CVD, using regression-based stepwise backward selection restrictive cubic spline models to express as...