A5057702951- Alzheimer's disease research and treatments
- Mitochondrial Function and Pathology
- Autophagy in Disease and Therapy
- ATP Synthase and ATPases Research
- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- COVID-19 and Mental Health
- Inflammasome and immune disorders
- Technology Use by Older Adults
- Memory and Neural Mechanisms
- Digital Mental Health Interventions
- Metabolism and Genetic Disorders
- Sirtuins and Resveratrol in Medicine
- Biochemical Acid Research Studies
- Endoplasmic Reticulum Stress and Disease
- Sphingolipid Metabolism and Signaling
- Stress Responses and Cortisol
East China Normal University
2019-2023
Introduction: With the global rise in elderly populations, demand for healthcare and long-term care services has grown, particularly addressing mental health. While AI shown promise health management of older adults, its effects on physical activity, health, their associations remain largely unexamined. Objective: This study aimed to investigate role improving among adults through promotion activity elucidating underlying mechanisms. Methods: Bibliometric methods, including CiteSpace...
Recent study has demonstrated that high-intensity interval training (HIIT) and moderate-intensity continuous (MICT) have the same effect to alleviate β-amyloid pathology in hippocampus of APPswe/PS1dE9 (APP/PS1) mice. Activation nucleotide binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is pivotal been accelerate accumulation. The present aimed examine whether exercise-induced reduction was associated with changes NLRP3 activation. APP/PS1...
Exercise plays a beneficial role in the management of Alzheimer's disease (AD), but its effects on brain metabolism are still far from being understood. Here, we examined behavioral changes APP/PS1 mice after high-intensity interval training (HIIT) and moderate-intensity continuous (MICT) analyzed metabolomics profiles hippocampus, cortex, hypothalamus by using nuclear magnetic resonance spectroscopy to explore potential metabolic mechanisms. The results demonstrate that both HIIT MICT...