A5075061856- Respiratory and Cough-Related Research
- Asthma and respiratory diseases
- IL-33, ST2, and ILC Pathways
- Pregnancy and preeclampsia studies
- Immune Cell Function and Interaction
- Inhalation and Respiratory Drug Delivery
- Congenital heart defects research
- Reproductive Biology and Fertility
- Biomedical and Engineering Education
- Emergency and Acute Care Studies
- Cardiovascular Issues in Pregnancy
- Health and Medical Research Impacts
- Antibiotic Use and Resistance
- Advances in Oncology and Radiotherapy
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal Respiratory Health Research
- CAR-T cell therapy research
- T-cell and B-cell Immunology
- Antibiotic Resistance in Bacteria
- Family and Patient Care in Intensive Care Units
- Birth, Development, and Health
Newcastle University
2020-2021
Newcastle upon Tyne Hospitals NHS Foundation Trust
2020-2021
St George's, University of London
2016-2020
The skin confers biophysical and immunological protection through a complex cellular network established early in embryonic development. We profiled the transcriptomes of more than 500,000 single cells from developing human fetal skin, healthy adult with atopic dermatitis psoriasis. leveraged these datasets to compare cell states across development, homeostasis, disease. Our analysis revealed an enrichment innate immune during first trimester clonal expansion disease-associated lymphocytes...
High consumption of irrational fixed‐dose combination (FDC) antibiotics may pose a threat antimicrobial resistance. In India, ampicillin–cloxacillin was the second highest sold FDC antibiotic behind amoxicillin and clavulanic acid. There remain, however, questions about its efficacy safety lack regulatory approval. We undertook literature review for to identify available data on used as FDC. identified 1071 studies screening 81 were considered inclusion. Only 12 in English language...
Abstract The human skin confers biophysical and immunological protection through a complex cellular network that is established early in development. We profiled ~500,000 single cells using RNA-sequencing from healthy adult developing skin, patients with atopic dermatitis psoriasis. Our findings reveal predominance of innate lymphoid macrophages contrast to T migratory dendritic skin. demonstrate dual keratinocyte differentiation trajectories activated circuits comprising vascular...
Searchable abstracts of presentations at key conferences on reproductive biology and medicine ISSN 2052-1472 (online)
<h3>Background</h3> In 2005 21.5% of NHS hospitals caring for children used Paediatric Early Warning Systems (PEWS) rising to 85% in 2013 and 100% 2018. However, there is great variation with 47 different parameters across the country. There has been a national drive led by England Improvement, Royal College Paediatrics Child Health Nursing develop standardized tool. One parameter that not ubiquitously parental concern. National PEWS surveys showed only one trust concern, 2018 this had risen...