Dongmei Yan

ORCID: 0000-0002-1525-3575
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About
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Research Areas
  • Biochemical and Molecular Research
  • Cancer, Hypoxia, and Metabolism
  • Gout, Hyperuricemia, Uric Acid
  • RNA modifications and cancer
  • HIV/AIDS drug development and treatment
  • Cancer-related Molecular Pathways

Hangzhou Medical College
2022

5-Fluorouracil (5-FU) has been widely applied in treating cancers. However, its usage is largely limited hepatocellular carcinoma (HCC), due to acquired resistance. Here, we aim identify target proteins and investigate their roles 5-FU sensitivity of HCC cells. Mass spectrometry (MS) proteomics was performed on 5-FU-resistant cell line (BEL7402/5-FU) parental (BEL7402) with treatment. In order potential targets, compared the between two groups used bioinformatics tools select hub from all...

10.1155/2022/6907057 article EN cc-by Disease Markers 2022-03-11
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