A5084310743- Nanoplatforms for cancer theranostics
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Electrochemical sensors and biosensors
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- Conducting polymers and applications
- Electrochemical Analysis and Applications
- Gas Sensing Nanomaterials and Sensors
- Immune Response and Inflammation
- Electrocatalysts for Energy Conversion
- Immune cells in cancer
- Luminescence and Fluorescent Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Transgenic Plants and Applications
- Pregnancy-related medical research
- Immune Cell Function and Interaction
- Viral gastroenteritis research and epidemiology
- ZnO doping and properties
- Manufacturing Process and Optimization
- Ga2O3 and related materials
- Advanced Photocatalysis Techniques
- Immunotherapy and Immune Responses
- Electrospun Nanofibers in Biomedical Applications
- Photonic Crystals and Applications
Chinese Academy of Sciences
2016-2025
Institute of Semiconductors
2024-2025
Chinese PLA General Hospital
2024-2025
University at Buffalo, State University of New York
2022-2025
Zhejiang Provincial People's Hospital
2010-2025
Hangzhou Medical College
2022-2025
Zhengzhou University
2009-2025
Changchun Institute of Applied Chemistry
2020-2024
University of Chinese Academy of Sciences
2018-2024
State Key Laboratory of Polymer Physics and Chemistry
2020-2024
We have developed a biocompatible antibacterial system based on polyethylene glycol functionalized molybdenum disulfide nanoflowers (PEG-MoS2 NFs). The PEG-MoS2 NFs high near-infrared (NIR) absorption and peroxidase-like activity, which can efficiently catalyze decomposition of low concentration H2O2 to generate hydroxyl radicals (·OH). conversion into ·OH avoid the toxicity has higher making resistant bacteria more vulnerable wounds easily cured. combine catalysis with NIR photothermal...
We report here a simple, high-yield yet low-cost approach to design single-layer MoS2 nanosheets with controllable size via an improved oleum treatment exfoliation process. By decorating chitosan, these functionalized have been developed as chemotherapeutic drug nanocarrier for near-infrared (NIR) photothermal-triggered delivery, facilitating the combination of chemotherapy and photothermal therapy into one system cancer therapy. Loaded doxorubicin could be controllably released upon effect...
The rising dangers of bacterial infections have created an urgent need for the development a new generation antibacterial nanoagents and therapeutics. A near-infrared 808 nm laser-mediated nitric oxide (NO)-releasing nanovehicle (MoS2 -BNN6) is reported through simple assembly α-cyclodextrin-modified MoS2 nanosheets with heat-sensitive NO donor N,N'-di-sec-butyl-N,N'-dinitroso-1,4-phenylenediamine (BNN6) rapid effective treatment three typical Gram-negative Gram-positive bacteria...
The ability to selectively destroy cancer cells while sparing normal tissue is highly desirable during the therapy.Here, magnetic targeted photothermal therapy was demonstrated by integration of MoS 2 (MS) flakes and Fe 3 O 4 (IO) nanoparticles (NPs), where converted near-infrared (NIR) light into heat NPs served as target moiety directed external field tumor site.The /Fe composite (MSIOs) functionalized biocompatible polyethylene glycol (PEG) were prepared a simple two-step hydrothermal...
Abstract Mild photothermal therapy (PTT), as a new anticancer therapeutic strategy, faces big challenges of limited accuracy and side‐effects due to uneven heat distribution. Here, near infrared triggered nitric oxide (NO) release nanocomposites based on bismuth sulfide (Bi 2 S 3 ) nanoparticles bis‐ N ‐nitroso compounds (BNN) are constructed for NO‐enhanced mild therapy. Upon 808 nm irradiation, the high conversion efficiency on‐demand NO realized simultaneously. Due unique properties NO,...
Abstract Current standard of care dressings are unsatisfactorily inefficacious for the treatment chronic wounds. Chronic inflammation is primary cause long‐term incurable nature Herein, an absorbable nanofibrous hydrogel developed synergistic modulation microenvironment to accelerate diabetic wound healing. The electrospun thioether grafted hyaluronic acid nanofibers (FHHA‐S/Fe) able form a in situ on bed. This degrades and absorbed gradually within 3 days. thioethers HHA can scavenge...
Immunotherapy has shown encouraging results in various cancers, but the response rates are relatively low due to complex tumor immunosuppressive microenvironment (TIME). The presence of tumor-associated macrophages (TAMs) and hypoxia correlates significantly with potent activity. Here, a hemoglobin-poly(ε-caprolactone) (Hb-PCL) conjugate self-assembled biomimetic nano red blood cell (nano-RBC) system (V(Hb)) is engineered deliver chemotherapeutic doxorubicin (DOX) oxygen for reprogramming...
Abstract Skin wound healing strategies that promote sustainable healing, prevent bacterial infections, and cause only mild irritation are urgently needed for open therapy. In this study, a system consists of reactive oxygen species (ROS)‐degradable hydrogel dressing, with encapsulated biosafe nitric oxide (NO) donor L‐arginine (L‐Arg), low level (100 × 10 −6 m ) the household disinfectant hydrogen peroxide (H 2 O is established therapy disinfection. Under stimulation H , NO sustainably...
Promoting the electron occupancy of active sites to unity is an effective method enhance oxygen evolution reaction (OER) performance spinel oxides, but it remains a great challenge. Here, in situ approach developed modify valence state octahedral Ni cations NiFe2O4 inverse via surface sulfates (SO42-). Different from previous studies, SO42- directly anchored on instead forming uncontrolled conversion or reconstruction. Experiment and theoretical calculations reveal precise adsorption spatial...
Near-infrared (NIR) laser induced phototherapy has been considered as a noninvasive option for cancer therapy. Herein, we report plasmonic PEGylated molybdenum oxide nanoparticles (PEG-MoOx NPs) that were synthesized by using facile hydrothermal method. The PEG-MoOx NPs exhibit broad absorption at the NIR biological window and remarkable photothermal conversion ability in first (808 nm) second (1064 windows. Moreover, biocompatible effective cellular uptake could be eliminated gradually from...
Chemotherapy resistance remains a major hurdle for cancer therapy in clinic because of the poor cellular uptake and insufficient intracellular release drugs. Herein, an intelligent, multifunctional MoS2 nanotheranostic (MoS2-PEI-HA) ingeniously decorated with biodegradable hyaluronic acid (HA) assisted by polyethyleneimine (PEI) is reported to combat drug-resistant breast (MCF-7-ADR) after loading chemotherapy drug doxorubicin (DOX). HA can not only target CD44-overexpressing MCF-7-ADR but...
Peroxidase-like activity of MoS<sub>2</sub> NFs was enhanced by cysteine modification which is beneficial to the detection glucose and H<sub>2</sub>O<sub>2</sub> a new catalytic mechanism proposed.
Rupture of the fetal membranes is a common harbinger imminent labor and delivery. Telomere shortening surrogate for oxidative stress (OS) senescence. Fetal leukocyte placental membrane DNA telomere lengths were evaluated to determine their association with preterm prelabor rupture (pPROM) or spontaneous births intact (PTB), compared term birth.Telomere quantified in cord blood leukocytes (n = 133) from three major groups: 1) pPROM 28), 2) PTB 69) 3) uncomplicated full (controls, n 35), using...
Supercapacitors are considered as potential innovation for energy storage owing to their long charge–discharge life and high power density. Herein, a simple industry-scalable approach was developed prepare the hybrid of Fe3O4-doped porous carbon nanorods (Fe3O4-DCN) supported by three-dimensional (3D) kenaf stem-derived macroporous (KSPC) high-performance supercapacitor, which prepared via pyrolyzing iron fumarate metal organic frameworks (MIL-88A, MIL stands Materials from Institut...
Tuning the electronic structure, morphology, and structure of electrocatalysts is great significance to achieve a highly active stable hydrogen evolution reaction (HER). Herein, combining hydrothermal low temperature phosphidation methods, V-doped Ni2P nanosheet arrays grown on carbon cloth (V-Ni2P NSAs/CC) were successfully prepared for HER. It found that V-Ni2P NSAs/CC exhibits preeminent performance Specifically, it only requires an overpotential 85 mV current density 10 mA cm-2 in 1.0 M...
Abstract Metal or metal oxides/carbon nanocomposites with hierarchical superstructures have become one of the most promising functional materials in sensor, catalysis, energy conversion, etc. In this work, novel Fe 3 O 4 /carbon been fabricated based on metal-organic frameworks (MOFs)-derived method. Three kinds Fe-MOFs (MIL-88A) different morphologies were prepared beforehand as templates and then pyrolyzed to fabricate corresponding superstructures. The systematic studies thermal...