A5100619696- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Tissue Engineering and Regenerative Medicine
- Polymer Surface Interaction Studies
- 3D Printing in Biomedical Research
- Hernia repair and management
- Surgical Sutures and Adhesives
- Orthopaedic implants and arthroplasty
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Nerve injury and regeneration
- Intestinal and Peritoneal Adhesions
- biodegradable polymer synthesis and properties
- Tracheal and airway disorders
- Hydrogels: synthesis, properties, applications
- Surface Modification and Superhydrophobicity
- Pelvic floor disorders treatments
- Dysphagia Assessment and Management
- Osteoarthritis Treatment and Mechanisms
- Voice and Speech Disorders
- Advanced Drug Delivery Systems
- Wound Healing and Treatments
- Graphene and Nanomaterials Applications
- ZnO doping and properties
- Nanoparticle-Based Drug Delivery
Hannam University
2014-2024
Chonnam National University
2007-2022
National Health Insurance Service
2019-2021
National Health Insurance Service Ilsan Hospital
2019-2021
Government of the Republic of Korea
2014-2021
Daejeon University
2021
Korea University
2016-2020
Kosin University Gospel Hospital
2019
Dankook University
2017
Electronics and Telecommunications Research Institute
1996-2016
Polyethylene oxide(PEO)-containing nonionic polymeric surfactants were studied as a possible means to produce PEO-rich surfaces by simple coating treatment of common hydrophobic medical material--polyethylene. Surface tension and adsorption properties PEO/polypropylene oxide(PPO) PEO/polybutylene oxide(PBO) block copolymer on surface (low density polyethylene, LDPE) investigated, using the Wilhelmy plate technique x-ray photoelectron spectroscopy(XPS). The protein resistance...
In this study, polycaprolactone (PCL) cylindrical scaffolds with gradually increasing pore size along the longitudinal direction were fabricated by centrifugation and thermal fibril-bonding process. The PCL scaffold showed a gradual (from ∼90 to ∼400 μm) porosity ∼80 ∼97%) axis. gradient was used investigate effect of on chondrogenic differentiation adipose stem cells (ASCs). From in vitro culture ASCs, it observed that section having range 370−400 μm provided more favorable environment for...
Porous scaffolds have been widely used in tissue engineering because they can guide cells and tissues to grow, synthesize extracellular matrix other biological molecules, facilitate the formation of functional organs. Although various natural synthetic biodegradable polymers fabricate scaffolds, more for since good mechanical strength, reproducible/controllable mechanical-chemical properties, controllable biodegradation rates. However, 'hydrophobic character' common is considered a...
The last decade has seen artificial blood vessels composed of natural polymer nanofibers grafted into human bodies to facilitate the recovery damaged vessels. However, electrospun (ENs) biocompatible materials such as chitosan (CTS) suffer from poor mechanical properties. This study describes design and fabrication a blend CTS PCL ENs coated with strands using rapid prototyping technology. resulting tubular exhibited excellent properties showed that this process may be useful for vascular...
Chitosans with different degree of acetylation (DA, 10-50%) were synthesized by the reaction deacetylated chitosan and acetic anhydride ratios. The porous beads (approx. 500 mum) fabricated from acetylated chitosans used to investigate degradation behaviors DA in vitro vivo. behavior was investigated solutions lysozyme and/or N-acetyl-beta-D-glucosaminidase (NAGase), which are enzymes for present human body. It observed that rate can be controlled adjusting value: increased increasing value...
Abstract Sol–gel transition temperature‐controllable Pluronic F127/F68 mixtures including mildly crosslinked alginate and nonsteroidal anti‐inflammatory drug (ibuprofen) were prepared to evaluate their potential as tissue adhesion barrier gels. The sol–gel temperatures of the could be controlled by adjusting ratio polymer concentration. with still flow property provided residence stability mixture gels in body. Ibuprofen was loaded reduce inflammatory response body and, thus, prevent...
Polycaprolactone (PCL)/Pluronic F127 nerve guide conduits (NGCs) with different surface pore structures (nano-porous inner vs. micro-porous surface) but similar physical and chemical properties were fabricated by rolling the opposite side of asymmetrically porous PCL/F127 membranes. The effect structure on peripheral regeneration through NGCs was investigated using a sciatic defect model rats. fibers tissues shown to have regenerated along longitudinal direction NGC nano-porous (Nanopore...
This study examined how the difference in pore size of porous scaffolds affected vitro chondrogenic differentiation seeded adipose stem cells (ASCs) and vivo cartilage repair ASC/scaffold construct. ASCs were isolated from 18 rabbits a poly (ε-caprolactone) (PCL) scaffold with different sizes (100, 200, 400 μm). The underwent induction under TGF-β 2 BMP-7 for 21 days before analysis. construct was also implanted on osteochondral defect created distal femur same rabbits, quality regeneration...