Uterine fibroids (leiomyomas and myomas) are the most common benign gynecological condition in patients presenting with abnormal uterine bleeding, pelvic masses causing pressure or pain, infertility obstetric complications. Almost a third of women need treatment due to symptoms. Objectives: In this review we present all currently available modalities for fibroids. Methods: An extensive search data regarding surgical, medical other options was conducted. Review: Nowadays, is intended control...

Background and Objectives: Infertility is a global problem. The interaction between depression infertility seems bidirectional, may negatively influence IVF outcomes. Beck Depression Inventory (BDI) one of the most extensively used instruments for diagnosing depression. aim this study was to assess dynamics in patients undergoing utilizing BDI. Materials Methods: This prospective cohort conducted at Clinic Gynecology Obstetrics University Clinical Center Serbia Belgrade, during year 2019....

Background and Objectives: Mutations in succinate dehydrogenase (SDH) fumarate hydratase (FH) give rise to various familial cancer syndromes, with these alterations being characteristic of certain types histomorphologically specific leiomyomas that hold significant predictive value. Materials Methods: This study presents two cases uterine exhibiting rare histomorphological genetic characteristics, which are crucial for prognosis further treatment. Results: Distinct histopathological features...

Aims The aim of this study was to determine non-occupational risk factors for bladder cancer in Serbia. Methods and design A hospital-based, case-control included 130 newly diagnosed patients the same number individually matched controls with respect sex, age (± 2 years) type residence (rural or urban), from Clinical Center Serbia Belgrade Kragujevac central took place June 1997 March 1999. Results According multivariate logistic regression analysis, there an association between: frequency...

Treatment of endometriosis prior to IVF/ICSI could be followed by the significant reduction ovarian reserve. The aim is identify potential markers outcome in patients with associated infertility and evaluate their clinical significance.The prospective cohort study included 73 primary caused that were subjected 77 cycles. Patients classified into two groups. In first group some type treatment had previously been applied, second immediately procedures.When pregnancy was achieved, there...

Introduction. Postpartum hysterectomy means at least 6 weeks after delivery or cesarean section. It is usually performed in life-threatening situations. Incidence of postpartum varies from 0.02% to 0.3% total number deliveries. Objective. The aim this study was show and compare the incidence section Institute Gynecology Obstetrics, Clinical Center Serbia. We compared two five-year periods: first period 1987-1982 second 2000-2004. Method. retrospective analyzed all patients treated Obstetrics...

Introduction. Transvaginal sonography and human chorionic gonadotropin (hCG) testing are cornerstones of modern clinical practice in cases with the suspected ectopic pregnancy. In unclear cases, if level hCG is above discriminatory zones, use uterine curettage recommended. There an increasing concern that strict observation guidelines would potentially harm otherwise normal early intrauterine pregnancies certain cases. Case Outline. A 35-year-old woman was admitted to hospital due a severe...

The objective of this investigation was to determine the percentage microinvasive and invasive cancers found when CIN 3 treated by hysterectomy. postoperative histologic findings all patients with conization or hysterectomy were analyzed. In 295 conization, 14 (4.75%) 11 (3.73%) found. Histologic analysis 106 specimens revealed carcinoma in (10.38%) 17 (16.04%) cases. finding unexpected cervical cancer seems significantly higher compared conization. One must be cautious avoid as primary mode...

Immature teratomas of the ovary represent less than 1% all ovarian teratomas. They contain several tissues that derive from three embryologic layers: ectoderm, mesoderm, and endoderm. We report case a 17-year-old girl who presented with an immature teratoma left recurred 3 months later as inoperable malignant neuroepithelial peritoneal tumor resembling glioblastoma. She died weeks after second explorative operation. The very aggressive course fast lethal outcome could be explained by...

The term "poor respond (POR) patients" is used for the group of women who badly to usual doses gonadotropins in vitro fertilization (IVF) treatments; consequence low pregnancy rate. A consensus was reached on minimal criteria needed define POR. At least two following three features must be present: 1. advanced maternal age (40 years or more) 2. previous POR (3 less oocytes with a conventional stimulation protocol) 3. abnormal ovarian reserve (AMH 0.5-1.1 ng/ml AFC 5-7).The aim find better...

Introduction: Whipple disease is a rare infectious caused by the bacterium Tropheryma whipplei. The classic form affects gastrointestinal and musculoskeletal systems; but other forms may damage heart, brain, or lungs. Due to non-specific diverse clinical symptoms, diagnosis of challenging often late. Adequate timely antibiotic treatment essential for favorable outcome. Case presentation: Here we present case young woman admitted gynecological clinic diagnostic laparoscopy suspected...

Placenta membranacea is a rare anomaly characterized by failure of villous atrophy during early gestation, and 30% cases involve some form placental adherence. percreta infrequent, but life-threatening condition. Antenatal diagnosis these anomalies very difficult, essential for reduction the number extent possible complications. A 19-year-old primigravida was referred to us with 31- week pregnancy complicated preeclampsia. Upon admission, ultrasound scan revealed eutrophic fetus in breech...

Heterotopic pregnancy is defined as the coincident existence of intrauterine and extrauterine gestations. The estimated incidence, without regard to manner conception, 1 in 7,000 pregnanc...

Introduction/Objective. Coronavirus pandemic caused most hospitals in the world to suspend regular activities. The aim of this study was analyze influence on patients who underwent hysterectomy with classical (abdominal) and minimally invasive surgery (laparoscopic vaginal approach) at Clinic for Gynecology Obstetrics University Medical Centre Serbia. Methods. There were 2446 hysterectomies five-year period. analyzed number types before during COVID-19 pandemic. Results. total operated...

Immature teratomas of the ovary represent less than 1% all ovarian teratomas. They contain several tissues that derive from three embryologic layers: ectoderm, mesoderm, and endoderm. We report case a 17-year-old girl who presented with an immature teratoma left recurred 3 months later as inoperable malignant neuroepithelial peritoneal tumor resembling glioblastoma. She died weeks after second explorative operation. The very aggressive course fast lethal outcome could be explained by...

Balkan endemic nephropathy (BEN) is interesting renal disease, because of its unique clinical, epidemiological and morphological characteristics: intensive interstitial fibrosis tubular atrophy without any inflammation. In the present paper we evaluate incidence BEN from point view for last decade. Therefore analyzed material obtained autopsies, kidney biopsies nephrectomy due to upper urothelial cancer (UUC) patients which were divided into two groups: those with permanent residence in...

Background and Objectives: Cervical squamous cell carcinoma (SCC) usually showed an infiltrative growth pattern into endocervical stroma. In rare cases, SCC spreads superficially as intraepithelial lesion to proximal uterine segments, more rarely, involves invasive aggressive behavior on secondary sites. Materials Methods: this study, we present the case of interesting form cervical discuss possible reasons for that presentation. Results: After clinical examination repeated...

There is serious concern about cancer risk in women undergoing ovarian stimulation treatment for infertility and longterm safety of these procedures. Association between fertility drugs still controversial. A 30-year-old woman was referred to our institution with the initial diagnosis an adnexal tumor after vitro fertilization. Her history revealed adnexectomy mucinous cystadenofibroma left ovary eight years ago, cystectomy due cystadenoma right three ago. At admission, most remarkable...

Introduction: Although large multiple myomas are a well-known cause of infertility, it is not uncommon to encounter pregnancy with such myomas. Management women controversial, both during and delivery. Such can also significant morbidity the puerperium. Caesarean section most common way Case report: A patient underwent cesarean myomectomy intraoperative cell salvage at 36 weeks gestation. Both fetal maternal outcomes were favorable. The lower uterine segment was accessible, despite presence...