Importance The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence its efficacy lacking. Objective To investigate the burst stimulation, which involves placement an implantable pulse generator connected to electrodes with leads that travel into epidural space posterior dorsal columns, in patients radiculopathy degenerative disorders. Design, Setting, and Participants This placebo-controlled, crossover, randomized clinical trial 50...

To compare the presence of cardiovascular (CV) risk factors and established CV disease in patients with psoriatic arthritis (PsA) general population to 10-year a fatal event calculated by Systematic Coronary Risk Evaluation (SCORE) algorithm.Patients PsA (n=338) controls (n=50 468) were recruited from Nord-Trøndelag Health Study 3. Age-adjusted sex-adjusted prevalence rates comorbidity SCORE algorithm was applied.There an increased angina pectoris (5.0% vs 3.6%, p=0.01), history percutaneous...

The risks of intracranial haemorrhage (ICH) associated with antithrombotic drugs outside clinical trials are gaining increased attention. aim this nationwide study was to investigate the risk ICH requiring hospital admission in users drugs.Data from Norwegian Patient Registry and Prescription Database were linked on an individual level. primary outcome incidence rates use drugs. Secondary endpoints fatal following assessed by Cox models. Among 3,131,270 individuals ≥18 years old observed...

A wide range in the prevalence (<0.01-0.25%) and incidence (0.5-23.1/100 000) of psoriatic arthritis (PsA) is reported. The main objective this study was to examine PsA central Norway.The patients were recruited from Nord-Trøndelag Health Study 3, a population carried out 2006-2008. All 94 194 inhabitants aged >20 years invited 50 806 (54%) responded. consisted questionnaire (Q1) brief medical examination. Q1 included questions if persons suffered psoriasis, rheumatoid (RA) or ankylosing...

Indications and optimal timing for surgical treatment of degenerative cervical myelopathy (DCM) remain unclear, data from daily clinical practice are warranted.To investigate outcomes following decompressive surgery DCM.Data were obtained the Norwegian Registry Spine Surgery. The primary outcome was change in neck disability index (NDI) 1 yr after surgery. Secondary endpoints European score (EMS), quality life (EuroQoL 5D [EQ-5D]), numeric rating scales (NRS) headache, pain, arm...

Objectives To compare clinical outcomes after decompressive surgery for central lumbar spinal stenosis ( LSS ) in individuals aged 80 and older with those of 18–79. Design Prospective data from the Norwegian Registry Spine Surgery. Setting Multicenter observational study. Participants Individuals undergoing at 36 orthopedic or neurosurgical departments (N = 1,503; 1,325 &lt;80 (median 66, range 21–79); 178 ≥80 82, 80–95)). Intervention Laminectomy microdecompression. Measurements Changes...

Adiposity is prevalent among patients with psoriatic arthritis (PsA). However, the temporal relation unclear. The present study was undertaken to investigate whether adiposity and body fat distribution are related risk of developing PsA, physical activity could modify possible risk.We included 36,626 women men from Norwegian Nord-Trøndelag Health Study without diagnosed PsA at baseline 1995 1997. Cox regression analysis used estimate adjusted hazard ratios (HRs) 95% confidence intervals (95%...

Background The risk of osteoporosis in patients with psoriatic arthritis (PsA) still remains unclear. aim this study was to investigate bone mineral density (BMD) at the hip and lumbar spine measured by dual-energy X-ray absorptiometry PsA. Methods From an outpatient clinic southern Norway, 140 PsA were consecutively recruited assessed for as part a prospective from January 2013 May 2014. An extensive data collection performed including demographic measures reflecting disease activity health...

Objective Psoriatic arthritis (PsA) can have a significant impact on health‐related quality of life (HRQoL). Data the timing changes in HRQoL patients with PsA are limited. The present study was undertaken to explore associations between sleep disturbance, fatigue, pain, anxiety, depression, general health status, and satisfaction before after diagnosis compared population. Methods Patients diagnosed Nord‐Trøndelag Health Study (HUNT2 [1995–1997] HUNT3 [2006–2008]) surveys were adjusted odds...

Abstract Background The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those younger (50–70 years) at 1 year. Methods Data were obtained the Norwegian Registry Spine Surgery (NORspine). Among 651 included, 177 (27.2%) years old. primary outcome change Neck Disability Index (NDI). Secondary changes European Myelopathy Score (EMS), quality life (EuroQoL EQ-5D), numeric...

To compare clinical outcomes following microdecompression surgery or laminectomy for central lumbar spinal stenosis (LSS) between patients with rheumatoid arthritis (RA) and without rheumatic disease.Data were collected from the Norwegian Registry Spine Surgery. The primary outcome was change in Oswestry Disability Index (ODI) score at 1 year. secondary endpoints health-related quality of life that measured using Euro-Qol-5D (EQ-5D), back pain numerical rating scale (NRS), leg NRS,...

Background The risk of osteoporosis in patients with psoriatic arthritis (PsA) remains unclear. aim this study was to compare bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) PsA and controls. Patients methods controls were recruited from the Nord-Trøndelag Health Study (HUNT) 3. Results (n=69) (n=11 703) comparable terms age (56.8 vs 55.3 years, p=0.32), gender distribution (females 65.2% 64.3%, p=0.87) postmenopausal status (75.6% 62.8%, p=0.08). Body mass...

Objectives The aim of this population-based study was to compare changes in cardiovascular (CV) risk factors over a decade-long period patients who developed psoriatic arthritis (PsA) and the background population. Methods Patients diagnosed with PsA (n=151) between 1998 2008 matched controls (n=755) participated both Nord-Trøndelag Health Study (HUNT) 2 (1995–1997) HUNT3 (2006–2008) were included. Mixed linear logistic models used analyse difference mean change HUNT2 for body mass index...

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Prospective pharmacoepidemiological study.To investigate the use of prescription opioids 2 years following degenerative lumbar spine surgery.There are limited data providing details to evaluate patterns opioid use. The number patients is often and on some most common surgical procedures lacking.Data from Norwegian Registry for Spine Surgery Prescription Database were linked an individual level. primary outcome measure was persistent second year after surgery. Functional disabilitywas...

Abstract Background Knowledge on breastfeeding among women with systemic lupus erythematosus (SLE) is sparse. We wanted to identify the frequency of in SLE, and compare SLE non-breastfeeding examine possible differences disease characteristics self-reported health data between groups. Methods Prospective from RevNatus, a consent-based Norwegian nationwide quality register was used for this study. Data were collected during January 2016 September 2021. registered at inclusion when planning...

Study Design. Observational multicenter study. Objective. The aim of this study was to evaluate changes in pain during sexual activity after surgery for lumbar spinal stenosis (LSS). Summary Background Data. There are limited data available on function patients undergoing LSS. Methods. Data were retrieved from the Norwegian Registry Spine Surgery. primary outcome change at 1 year, assessed by item number eight Oswestry disability index questionnaire. Secondary measures included Disability...

<ns4:p><ns4:bold>Background </ns4:bold>A wide range of antithrombotic medications can be used in the prevention and treatment thrombosis. Among hemorrhagic complications drugs, intracranial hemorrhage may have particularly devastating consequences with high morbidity, disability mortality rates. The incidence risks patients on treatments from regular clinical practice outside trials remain largely unknown. It is not known if results extrapolated to everyday practice. We will conduct a...

Study design Prospective pharmacoepidemiological study. Objective To investigate the use of prescription opioids two years following degenerative lumbar spine surgery. Summary background data There are limited providing details to evaluate patterns opioid use. The number patients is often and on some most common surgical procedures lacking. Methods Data from Norwegian Registry for Spine Surgery Prescription Database were linked an individual level. primary outcome measure was persistent...

Abstract Purpose To compare patient-reported outcomes (PROMs) following surgery for degenerative cervical myelopathy (DCM) among patients with rheumatoid arthritis (RA) or ankylosing spondylitis (AS) versus those without rheumatic diseases. Methods Data were obtained from the Norwegian Registry Spine Surgery. The primary outcome was change in Neck Disability Index (NDI) at 1 year. Secondary endpoints included European Myelopathy Score (EMS), quality of life (EuroQoL-5D [EQ-5D]), numeric...

Diabetic muscle infarction is a rare but under-reported complication of diabetes mellitus. The condition characteristically affects poorly-controlled type 1 diabetic patients with severe microvascular complications. In most the reported cases, have not presented until several weeks into illness and serum creatine kinase levels were elevated. We describe case occurring in 2 patient no evidence significant retinopathy, neuropathy or nephropathy. Due to acute presentation our patient, we are...

<h3>Background</h3> The use of TNF-inhibitors in psoriatic arthritis (PsA) has been s<b>h</b>own to improve clinical and radiographic outcome randomized controlled trials (RCT) shown be well tolerated with a rather low rate drop outs. However, patients RCT may not representative followed ordinary practice. <h3>Objectives</h3> To assess drug survival TNF-inhibitor treatment PsA treated an rheumatology clinic Norway. <h3>Methods</h3> were recruited from All this are monitored measures data is...

<h3>Background</h3> Controversies exist regarding increased risk of cardiovascular (CV) disease in patients with psoriatic arthritis (PsA). <h3>Objectives</h3> To compare the presence CV factors and PsA normal population. Further to estimate 10-year a fatal event by using Systematic Coronary Evaluation (SCORE) algorithm.¹ <h3>Methods</h3> Patients control subjects were recruited from Nord-Trøndelag Health Study (HUNT) 3, diagnoses (n=338) verified according Classification...