A5003305153- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Hemoglobinopathies and Related Disorders
- Blood transfusion and management
- Climate Change and Health Impacts
- Diabetes and associated disorders
- Outdoor and Experiential Education
- Health, psychology, and well-being
- Streptococcal Infections and Treatments
- Blood disorders and treatments
- Infective Endocarditis Diagnosis and Management
Australian Red Cross Lifeblood
2018-2024
Queensland University of Technology
2023-2024
The University of Melbourne
2023-2024
Victorian Aboriginal Health Service
2024
The distribution of RBC antigens, which define blood group types, differs among populations. In contrast to many world populations, profiles for Indigenous Australians have not been well studied. As it is now possible predict comprehensive antigen from genomic data sets, we aimed apply this and provide a comparison other major populations.Whole exome sequence 72 Western Desert was provided by the Telethon Kids Institute. Variants (against hg19) were annotated using computer software...
Red cell (RC) alloantibodies occur on exposure to non-self RC antigens in transfusion and pregnancy (typically IgG clinically significant) or association with non-RC immune environmental factors IgM not significant). In Australia, the risk of alloimmunisation First Nations peoples is unknown. We assessed epidemiology, specificity, antecedents via a data linkage retrospective cohort study Northern Territory (NT) intensive care unit (ICU) patients (2015–2019). Of 4183 total patients, 50.9%...
Hematological disorders are often treated with blood transfusions. Many group antigens and variants population-specific, for patients rare types, extensive donor screening is required to find suitable matches transfusion. There a scarcity of knowledge regarding in Aboriginal Australian populations, despite higher need transfusion due the prevalence renal diseases anaemia.
Abstract Background We report an obstetric case involving RhD‐positive woman who had developed a red blood cell (RBC) antibody that was not detected until after delivery of newborn, presented with positive direct antiglobulin test result. Immunohematology studies suggested the maternal directed against low‐prevalence antigen on paternal and newborn RBCs. Results Comprehensive group profiling by targeted exome sequencing revealed novel nonsynonymous single nucleotide variant (SNV) RHCE...
Limited evidence exists on the distribution of ABO RhD blood groups and prevalence specificity red cell (RBC) alloantibodies in Aboriginal Torres Strait Islander peoples Australia. We investigated RBC alloantibody patients undergoing cardiac surgery at a South Australian (SA) tertiary hospital, major surgical referral centre for Northern Territory (NT) METHODS: Retrospective analysis all consecutive Flinders Medical Centre (FMC) between January 2014 June 2019. groups, prevalence,...
Transgenerational trauma continues to have detrimental impacts on Indigenous Australians. However, Australians always recognised that the healing from colonisation’s traumatic policies lies within culture. As such, there is an urgent need for community-driven culturally safe, well-being support, particularly young people. The development of adventure-based therapy programme aims support and improve emotional social people in North Queensland. We aim evaluate this novel using validated...
Background and Objective: Limited evidence exists on the distribution of ABO RhD blood groups less prevalence specificity red cell (RC) alloantibodies in Aboriginal Torres Strait Islander peoples Australia. The study aimed to determine RC patients undergoing cardiac surgery at a South Australian tertiary hospital.Materials Methods: Retrospective analysis group alloantibody data time until 2021 for all consecutive Flinders Medical Centre (FMC) between January 2014 June 2019. Incidence,...