A5067415258- Shoulder Injury and Treatment
- Bone health and osteoporosis research
- Hip and Femur Fractures
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- Nutrition and Health in Aging
- Vitamin D Research Studies
- Peripheral Nerve Disorders
- Bone and Joint Diseases
- Elbow and Forearm Trauma Treatment
- Obstructive Sleep Apnea Research
- Myofascial pain diagnosis and treatment
- Bone fractures and treatments
- Sports injuries and prevention
- Glioma Diagnosis and Treatment
- Muscle Physiology and Disorders
- Orthopaedic implants and arthroplasty
- Pain Management and Treatment
- Epigenetics and DNA Methylation
- Musculoskeletal pain and rehabilitation
- Bone Metabolism and Diseases
- Mesenchymal stem cell research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroscience of respiration and sleep
- Shoulder and Clavicle Injuries
University of Rome Tor Vergata
2015-2024
Bambino Gesù Children's Hospital
2023-2024
University of Chieti-Pescara
2022-2024
Policlinico Tor Vergata
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023
The Italian Society for Orthopaedics and Traumatology conceived this guidance—which is primarily addressed to orthopedic surgeons, but should also prove useful other bone specialists general practitioners—in order improve the diagnosis, prevention, treatment of osteoporosis its consequences. Literature reviews by a multidisciplinary team. following topics are covered: role instrumental, metabolic, genetic evaluations in diagnosis osteoporosis; appraisal risk fracture thresholds intervention;...
Despite the high level achieved in field of shoulder surgery, a global consensus on rotator cuff tears management is lacking. This work divided into two main sessions: first, we set questions about hot topics involved tears, from etiopathogenesis to surgical treatment. In second, answered these by mentioning Evidence Based Medicine. The aim present provide easily accessible guidelines: they could be considered as recommendations for good clinical practice developed through process systematic...
Despite the high level achieved in field of shoulder surgery, a global consensus on rotator cuff tears management is lacking.This work divided into two main sessions: first, we set questions about hot topics involved tears, from etiopathogenesis to surgical treatment.In second, answered these by mentioning Evidence Based Medicine.The aim present provide easily accessible guidelines: they could be considered as recommendations for good clinical practice developed through process systematic...
Abstract Pentraxin 3 (PTX3) is a multifunctional glycoprotein regulating inflammatory response, cell proliferation and migration deposition remodelling of the extracellular matrix by variety cells. In this study, we investigated possible role PTX3 in bone homeostasis. To end, compared expression function human osteoblasts osteoporotic, osteoarthritic patients young subjects not affected diseases. Immunohistochemical analysis performed on head biopsies showed close association between health...
Sarcopenia, osteoporosis and osteoarthritis are the most frequent musculoskeletal disorders affecting older people. The main aim of this study was to test hypothesis that balance between BMPs myostatin pathways regulates age-related muscle degeneration in OP OA patients. To end, we investigated relationship among expression BMP-2/4-7, phosphorylated Smads1-5-8 quality, evaluated term fibers atrophy satellite cells activity. In retrospective study, collected 123 biopsies vastus lateralis: 48...
Age-related bone diseases, such as osteoarthritis and osteoporosis, are strongly associated with sarcopenia muscle fiber atrophy. In this study, we analyzed biopsies in order to demonstrate that, patients, both osteophytes formation regenerative properties of stem cells related the same factors. particular, thanks immunohistochemistry, transmission electron microscopy, immunogold labeling investigated role BMP-2 activity. patients immunohistochemistry microscopy allowed us note a higher...
Plantar fasciopathy presents with pain at the plantar and medial aspect of heel. If chronic, it can negatively impact on quality life. is not always self-limiting, be debilitating.Surgical management involves different procedures. We describe a percutaneous fascia release. A minimally invasive access to tuberosity calcaneus performed, small scalpel blade used release fascia.With this procedure, skin healing problems, nerve injuries, infection prolonged recovery time are minimised, allowing...
Obstructive sleep apnea (OSA) and low bone mineral density (BMD) are 2 prevalent conditions with a significant negative impact on patients' well-being quality of life. Recent research has shown BMD at different sites in male patients OSA. Although the efficacy continuous positive airway pressure (CPAP) treatment for OSA been widely demonstrated, evidence understanding its other bone-related outcomes is insufficient. The aim this observational study was to investigate effect 12 months CPAP...
This work provides easily accessible guidelines for the diagnosis, treatment and rehabilitation of Achilles tendon ruptures.These could be considered as recommendations good clinical practice developed through a process systematic review literature expert opinion, to improve quality care individual patient rationalize use resources.This is divided into two sessions: 1) questions about hot topics; 2) answers following Evidence Based Medicine principles.Despite frequency pathology high level...
The Vitamin D Receptor (VDR) mediates the actions of 1,25-Dihydroxvitamin D3 (1,25(OH)2D3), which has important roles in bone homeostasis, growth/differentiation cells, immune functions, and reduction inflammation. Emerging evidences suggest that epigenetic modifications VDR gene, particularly DNA methylation, may contribute to onset progression many human disorders. This review aims summarize available information on role methylation signatures different pathological contexts, including...
Intra-articular and peri-articular hyaluronic acid (HA) injections are widely used to treat several musculoskeletal pathologies.Although clinical I.S.Mu.