A5077140018- Bone health and osteoporosis research
- Hip and Femur Fractures
- Bone fractures and treatments
- Nutrition and Health in Aging
- Bone and Joint Diseases
- Bone Metabolism and Diseases
- Bone health and treatments
- Shoulder Injury and Treatment
- Orthopaedic implants and arthroplasty
- Vitamin D Research Studies
- Muscle Physiology and Disorders
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Tendon Structure and Treatment
- Orthopedic Infections and Treatments
- Biomarkers in Disease Mechanisms
- Osteoarthritis Treatment and Mechanisms
- Body Composition Measurement Techniques
- Spinal Fractures and Fixation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Sports injuries and prevention
- Spine and Intervertebral Disc Pathology
- Spaceflight effects on biology
- Total Knee Arthroplasty Outcomes
Policlinico Tor Vergata
2016-2025
University of Rome Tor Vergata
2016-2025
Catholic University Our Lady of Good Counsel
2024
University of Campania "Luigi Vanvitelli"
2024
Società Italiana di Nefrologia
2020
Italian Society of Physiotherapy
2018
Health Economics and Outcomes Research (United Kingdom)
2011
University of Pennsylvania
2011
Sapienza University of Rome
2004
Istituto di Sessuologia Clinica
1991
The purpose of this document, a result the harmonisation and revision Guidelines published separately by SIMFER, SIOMMMS/SIR, SIOT associations, is to provide practical indications based on specific levels evidence various grades recommendations, drawn from available literature, for management osteoporosis diagnosis, prevention, treatment fragility fractures. These were discussed formally approved delegates Italian Scientific Associations involved in project (SIE, SIGG, SIMG, SIMI, SIOMMMS,...
Abstract We previously showed that Irisin, a myokine released from skeletal muscle after physical exercise, plays central role in the control of bone mass. Here we report treatment with recombinant Irisin prevented loss hind-limb suspended mice when administered during suspension (preventive protocol) and induced recovery mass were injected due to period 4 weeks (curative protocol). MicroCT analysis femurs r-Irisin preserved both cortical trabecular mineral density, dramatic decrease volume...
The Italian Society for Orthopaedics and Traumatology conceived this guidance—which is primarily addressed to orthopedic surgeons, but should also prove useful other bone specialists general practitioners—in order improve the diagnosis, prevention, treatment of osteoporosis its consequences. Literature reviews by a multidisciplinary team. following topics are covered: role instrumental, metabolic, genetic evaluations in diagnosis osteoporosis; appraisal risk fracture thresholds intervention;...
ANDREOLI, A., M. MONTELEONE, VAN LOAN, L. PROMENZIO, U. TARANTINO, and A. DE LORENZO. Effects of different sports on bone density muscle mass in highly trained athletes. Med. Sci. Sports Exerc., Vol. 33, No. 4, 2001, pp. 507–511. Purpose: It is known that participating can have a beneficial effect mass. However, it not well established which sport more for increased mineral (BMD) appendicular (AMM). This study investigated the effects high-intensity activities BMD AMM Materials Methods:...
Abstract Dendritic cells (DCs) are thought to play a key role in driving the immunopathogenic response underlying chronic inflammatory arthritis. In this study, we have examined presence and phenotype of plasmacytoid DCs (pDCs) synovial fluids (SF) patients with rheumatoid arthritis (RA), psoriatic (PA), osteoarthritis (OA) determined chemotactic properties SF from these toward pDCs. Flow cytometry analysis showed that percentage pDCs, identified as population Lin−CD123++ cells, is 4- 5-fold...
Patients with low back pain frequently demonstrate recumbent magnetic resonance imaging (MRI) alterations not always related to homogeneous clinical symptoms. The purpose of this study was evaluate and quantify the statistical significance variations some anatomical parameters lumbosacral spine reveal occult disc pathologies from upright position in patients acute chronic pain.Fifty-seven complaining (27 women, 30 men) underwent dynamic MRI a 0.25-T tilting system (G-scan Esaote). We settled...
Despite the high level achieved in field of shoulder surgery, a global consensus on rotator cuff tears management is lacking. This work divided into two main sessions: first, we set questions about hot topics involved tears, from etiopathogenesis to surgical treatment. In second, answered these by mentioning Evidence Based Medicine. The aim present provide easily accessible guidelines: they could be considered as recommendations for good clinical practice developed through process systematic...
Introduction: Frailty is a condition characterized by reduced resistance to low-level stress events, resulting from the progressive decline of multiple physiological systems observed with aging. Many factors can contribute pathogenesis frailty, and nutritional status appears play key role. The objective study was investigate relationship between status, evaluated using Mini Nutritional Assessment (MNA), frailty among older people. Patients methods: An observational carried out at University...
Sarcopenia is the age-associated loss of skeletal muscle mass and function. It a major clinical problem for older people research in understanding pathogenesis, consequences, management, socioeconomic burden this condition growing exponentially. The causes sarcopenia are multifactorial, including inflammation, insulin resistance, changing endocrine function, chronic diseases, nutritional deficiencies low levels physical activity. Operational definition combines assessment mass, strength...
Bone metabolism is affected by mechanical, genetic, and environmental factors plays a major role in osteoporosis. Nevertheless, the influence of pollution on occurrence osteoporosis still unclear controversial. In this context, heavy metals are most important pollutants capable to affect bone mass. The aim study was investigate whether accumulation tissues could be related altered architecture osteoporotic patients. To end, we analyzed 25 head biopsies patients osteoarthritic Moreover...
The response of human primary osteoblasts exposed to simulated microgravity has been investigated and analysis metabolomic proteomic profiles demonstrated a prominent dysregulation mitochondrion homeostasis. Gravitational unloading treatment induced decrease in mitochondrial proteins, mainly affecting efficiency the respiratory chain. Metabolomic revealed that influenced several metabolic pathways; stimulating glycolysis pentose phosphate pathways, while Krebs cycle was interrupted at...
Despite the high level achieved in field of shoulder surgery, a global consensus on rotator cuff tears management is lacking.This work divided into two main sessions: first, we set questions about hot topics involved tears, from etiopathogenesis to surgical treatment.In second, answered these by mentioning Evidence Based Medicine.The aim present provide easily accessible guidelines: they could be considered as recommendations for good clinical practice developed through process systematic...
ABSTRACT Irisin is a myokine produced by skeletal muscle during exercise in both mice and humans. We previously showed that irisin treatment ameliorates immobility-induced osteoporosis muscular atrophy mice. Data humans positive association between bone mineral density (BMD) athletes population of healthy children. However, the role this regarding state same remained to be determined. For purpose, 62 patients (age 68.71 ± 12.31 years) undergoing total hip or knee replacement were recruited....