Karen M. Keane

ORCID: 0000-0002-1572-9211
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About
Contact & Profiles
Research Areas
  • Exercise and Physiological Responses
  • Phytochemicals and Antioxidant Activities
  • Muscle metabolism and nutrition
  • Sports Performance and Training
  • Sports injuries and prevention
  • Antioxidant Activity and Oxidative Stress
  • Neurological Disease Mechanisms and Treatments
  • Cardiovascular and exercise physiology
  • Bone health and osteoporosis research
  • Nuts composition and effects
  • Nutritional Studies and Diet
  • Protease and Inhibitor Mechanisms
  • Botanical Research and Applications
  • Retinoids in leukemia and cellular processes
  • Pomegranate: compositions and health benefits
  • Metabolomics and Mass Spectrometry Studies
  • Adipose Tissue and Metabolism
  • Bone fractures and treatments
  • Genetics and Physical Performance
  • Bee Products Chemical Analysis
  • Thermoregulation and physiological responses
  • Neurological Disorders and Treatments
  • Vitamin D Research Studies
  • Innovative Teaching Methods
  • Muscle activation and electromyography studies

Galway-Mayo Institute of Technology
2021-2024

Technological University Dublin
2023-2024

Atlantic Technological University
2022-2024

Northumbria University
2015-2022

Longwood University
2019

Center for Health, Exercise and Sport Sciences
2015-2017

Eli Lilly (United Kingdom)
2016

University of Bath
2016

North-West University
2015

Ollscoil na Gaillimhe – University of Galway
2011

To evaluate the plasma bioavailability of betanin and nitric oxide (NOx) after consuming beetroot juice (BTJ) whole (BF). BTJ BF were also analysed for antioxidant capacity, polyphenol content (TPC) betalain content.Ten healthy males consumed either 250 ml BTJ, 300 g or a placebo drink, in randomised, crossover design. Venous samples collected pre (baseline), 1, 2, 3, 5 8 h post-ingestion. Betanin was with reverse-phase high-performance liquid chromatography (HPLC) mass spectrometry...

10.1007/s00394-016-1173-5 article EN cc-by European Journal of Nutrition 2016-02-12

This study examined whether beetroot juice (BTJ) would attenuate inflammation and muscle damage following a marathon. Using double blind, independent group design, 34 runners (each having completed ca. ∼16 previous marathons) consumed either BTJ or an isocaloric placebo (PLA) for 3 days Maximal isometric voluntary contractions (MIVC), countermovement jumps (CMJ), soreness, serum cytokines, leucocytosis, creatine kinase (CK), high sensitivity C-reactive protein (hs-CRP), aspartate...

10.1139/apnm-2016-0525 article EN Applied Physiology Nutrition and Metabolism 2016-11-09

The purpose of this study was to investigate the effects Montmorency tart cherry juice ( MC ) on nitric oxide NO biomarkers, vascular function, and exercise performance. In a randomized, double‐blind, placebo PLA )‐controlled, crossover study, 10 trained cyclists (mean ± SD ; O 2peak 59.0 7.0 mL/kg/min) acutely ingested 30 mL either or following dietary restrictions polyphenol‐rich compounds completed 6‐minutes moderate‐ severe‐intensity cycling bouts 1.5 hour post‐ingestion 2 occasions for...

10.1111/sms.13088 article EN Scandinavian Journal of Medicine and Science in Sports 2018-03-22

Abstract Cerebral blood volume and metabolism of oxygen decline as part human ageing, this has been previously shown to be related cognitive decline. There is some evidence suggest that polyphenol-rich foods can play an important role in delaying the onset or halting progression age-related health disorders such CVD Alzheimer’s disease improve function. In present study, acute, placebo-controlled, double-blinded, cross-over, randomised Latin-square design study with a washout period at least...

10.1017/s0007114516004177 article EN British Journal Of Nutrition 2016-12-14

An initial bout of eccentric exercise is known to protect against muscle damage following a repeated the same exercise; however, neuromuscular adaptations owing this phenomenon are unknown.To determine whether disturbances modulated exercise.Following performed with elbow flexors, we measured maximal voluntary force, resting twitch soreness, creatine kinase (CK) and activation (VA) using motor point cortex stimulation at baseline, immediately post-exercise 1, 2, 3, 4 7 days on two occasions,...

10.1111/apha.12844 article EN Acta Physiologica 2016-12-17

Exercise-induced muscle damage (EIMD) is a well-investigated area, however there paucity of data surrounding the response in females. The aim this study was to examine responses from sport-specific bout repeated sprints female athletes. Eleven well-trained females (mean ± SD; age: 22 3 years; height: 166.6 5.7 cm; mass: 62.7 4.5 kg) luteal phase menstrual cycle completed sprint protocol designed induce EIMD (15 × 30 m sprints). Creatine kinase, countermovement jump height, knee extensor...

10.1519/jsc.0000000000000961 article EN The Journal of Strength and Conditioning Research 2015-04-08

Abstract Tart Montmorency cherries (MC) are a particularly rich source of anthocyanins and other polyphenols that have been shown to elicit antioxidant, anti-inflammatory vasomodulatory actions. The current study aimed determine the influence chronic MC supplementation on cognitive function mood. In 3-month double-blinded, placebo-controlled parallel study, middle-aged adults (mean ± sd : 48 6 years) were randomly assigned either 30 ml twice daily ( n 25) or same amount an isoenergetic...

10.1017/s0007114522000460 article EN cc-by British Journal Of Nutrition 2022-02-03

Tart Montmorency cherries (MC) have been shown to be rich in anthocyanins and other phytochemicals known anti-inflammatory properties influence pathways that might improve cardiometabolic health. However, there is limited evidence for the longer-term use of tart on these indices. The aim current study was investigate MC concentrate health indices following a 3-month supplementation period. Fifty middle-aged adults (34 males 16 females; mean ± SD age: 48 6 years BMI: 27.6 3.7 kg/m2) completed...

10.3390/nu13051417 article EN Nutrients 2021-04-23

The purpose of this study was to examine student use and perceptions technology enhanced learning tools (TELTs), including their value for learning. Students enrolled onto a 12-week undergraduate science module had access four TELTs each week, (i) recording the lecture (Panopto™), (ii) an animated mini review (ShowMe), (iii) multiple choice quiz hosted on Blackboard® (MCQ), (iv) Twitter feed. Ninety-five students completed survey at end module, which included quantitative qualitative...

10.1186/s41239-017-0078-6 article EN cc-by International Journal of Educational Technology in Higher Education 2017-11-17

Food high in (poly)phenolic compounds, such as anthocyanins, have the potential to improve exercise recovery and performance. Haskap berries are rich but no research has examined human The aim of this study was determine influence berry on parameters endurance running performance.Using a double-blind, placebo controlled, independent groups design, 30 male recreational runners (mean ± SD age, 33 7 years; stature, 178.2 7.2 cm; mass, 77.7 10.6 kg; V˙O2peak, 52.2 6.6 mL/kg/min) volunteered...

10.3390/nu14040780 article EN Nutrients 2022-02-13

ABSTRACT Ladies Gaelic football (LGF) is a traditional, amateur sport played by female athletes. LGF an invasion-based field involving high-intensity, intermittent match play. There currently paucity of research on intercounty (elite level) despite growing interest in the male version game. This article aims to provide strength and conditioning recommendations for with particular focus level Recommendations within this include needs analysis, injury epidemiology, physical physiological...

10.1519/ssc.0000000000000761 article EN Strength and conditioning journal 2023-01-25

Clonal T cells undergo programmed cell death (PCD) or apoptosis when cultured without the appropriate cytokines. The cysteine protease, IL-1 beta converting enzyme (ICE), is implicated in based on its structural similarity to PCD gene, ced-3, Caenorhabditis elegans and induction of fibroblasts transfected with recombinant ICE. We show that murine IL-2-dependent CTLL line expresses ICE but not beta. Interestingly, mRNA protein levels increase during apoptosis. Yet inhibition enzymatic...

10.4049/jimmunol.155.7.3433 article EN The Journal of Immunology 1995-10-01

Endurance athlete performance is greatly dependent on sufficient post-race system recovery, as endurance races have substantial physiological, immunological and metabolic effects these athletes. To date, the of numerous recovery modalities been investigated, however, very limited literature exists pertaining to athletes after without utilisation modalities. As such, this investigation aimed at identifying trend within 48 h a marathon. Serum samples 16 collected 24 before, immediately after,...

10.1038/s41598-020-67884-9 article EN cc-by Scientific Reports 2020-07-06
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