Abstract The Corneometer CM® 825 from Courage & Khazaka electronic GmbH is widely utilized in clinical efficacy testing of cosmetics. Assessing methodological variables crucial for ensuring the reliability process. aim this study was to evaluate operational and instrumental parameters assessment skin hydration levels. Precision accuracy measurements were assessed by measuring levels on 10 participants specific areas forearm face. Three different conditions (dry, normal, hydrated)...

This study aimed to assess the effect of 1,3-propanediol at different concentrations (5%, 10%, or 15%), either applied alone in combination with butylene glycol (BG) (5%) and/or glycerol (5%), on skin hydration and barrier function. The measurements were conducted using capacitance determine trans epidermal water loss (TEWL) rates evaluate

The emollients are important ingredients used in skincare formulations that can act as moisturizing agents through their occlusive potential, preventing skin water loss. Consumer interest natural and sustainable products has grown considerably the last few years, requiring efforts from cosmetic industry to design with raw materials of natural, organic, origin. Thus, it is essential improve knowledge about behavior be alternatives synthetic ingredients.This work aimed evaluate performance...

ABSTRACT Liquid-Crystalline Systems represent active compounds delivery systems that may be able to overcome the physical barrier of skin, especially represented by stratum corneum. To obtain these systems, aqueous and oily components are used with surfactants. Of different association structures in such liquid-crystalline offer numerous advantages a topical product. This manuscript presents development consisting, which oil component is olive oil, its rheological characterizations, location...

Iontophoresis is a noninvasive technique, based on the application of constant low-intensity electric current to facilitate release variety drugs, whether ionized or not, through biological membranes. The objective this research was evaluate effect iontophoresis using different intensities uptake fluoride in dental enamel with artificial caries lesions. In vitro operator-blind experiment, bovine blocks (n = 10/group) caries-like lesions and predetermined surface hardness were randomized into...

Abstract Background The use of antioxidants in applications for topical seems promising, however, many studies must be performed to ensure processes and products that can effectively bring benefits combat the action free radicals skin. For effective against from skin, it is essential compounds permeate different skin layers, reach deeper layers epidermis active form stay there a sufficient time cause beneficial effects. Aim This work aimed evaluate antioxidant formulations with phenolic as...

Formulations with lyotropic liquid crystals were prepared from a Brazilian nut vegetable oil, guarana extract and combination of sorbitan monooleate (Span 80) monolaurate ethoxylate EO 20 (Tween 20) in the ratio 1:3 (surfactant component) their physical–chemical aspects rheological properties determined. Compositions found pseudoternary diagram surfactant range 70–90% polarized light microscopy, small-angle x-ray scattering (SAXS) showed them to be lamellar. The preparations furthermore...

Abstract Background New technologies, such as sonic devices, have been developed to optimize the skin cleansing process and improve its efficiency. To evaluate effectiveness of these cosmetic procedures, bioengineering is an objective method assess biophysical parameters skin. Aims This study aimed effect facial on physiological properties by comparing a with product applied manually associated use electric device. Patients/Methods A gentle cleanser was entire face 12 subjects; device used...

Dermatoporosis defines the progressive chronic cutaneous insufficiency syndrome. Stage I is characterized by atrophy, senile purpura, and stellate pseudoscars.To assess clinical, histologic, quality of life, biophysical effects oral and/or topical hydrolyzed collagen (HC) on forearm skin postmenopausal women with stage I.Double-blind randomized placebo-controlled factorial design study. Two groups menopausal dermatoporosis forearms were to HC 5 g/day or matching placebo, also serum 2.5%...

Abstract Background The intracellular form of action retinoids requires these agents to reach deeper layers the skin with viable cells ensure therapeutic efficiency. However, studies on swine models show that some have low permeability. Thus, association innovative formulations technological strategies involving physical permeation promoters can be employed increase permeability this active, ensuring a targeting effect active. Aims In study, it was proposed development and evaluation release...

Acne is an inflammatory skin condition that develops in pilosebaceous follicles, affecting mainly the onset of puberty.Among numerous chemicals with dermatological and cosmetic purpose, traded prescribed, raw materials mineral origin have been often sought formulations aimed at treating / or preventing acne.This work development preparations including green clay sensory analysis formulations.Four containing 2.5 % to 5 clay, presence absence dimethicone were prepared.The rheological behavior...

Background:: In several countries, still there is no standardized regulation on the use of claims. However, are some guideline materials and content that used by regulatory agencies. Objective:: The goal this manuscript to provide an approach understanding thematic cosmetic claims dermatologists general practice physicians. objective discuss definition, framework tips help them how knowledge guarantee assertive indication. Results:: Knowing appropriate tests for substantiation allows...