Yiwei Chen

ORCID: 0000-0002-1620-4353
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About
Contact & Profiles
Research Areas
  • Orthopedic Infections and Treatments
  • Sleep and related disorders
  • Neutropenia and Cancer Infections
  • Surgical site infection prevention
  • Knee injuries and reconstruction techniques
  • Osteoarthritis Treatment and Mechanisms
  • Cancer Immunotherapy and Biomarkers
  • Ferroptosis and cancer prognosis
  • Musculoskeletal synovial abnormalities and treatments
  • Treatment of Major Depression
  • Sleep and Wakefulness Research
  • Endoplasmic Reticulum Stress and Disease

Shanghai Sixth People's Hospital
2024-2025

Shanghai Jiao Tong University
2024-2025

Beijing Tian Tan Hospital
2025

Capital Medical University
2025

Andre Abrasive Articles (Poland)
2024

TIE Kinetix (Germany)
2024

The infrapatellar fat pad and synovium are the sites of immune cell infiltration origin proinflammation. Studies have shown that Hoffa's synovitis may be a sign early-stage osteoarthritis (OA). However, there been no effective interventions specifically for synovitis. We will conduct multicentre, multi-blind (participant, physician, outcome assessor data analyst blinded) randomised controlled trial to compare effectiveness an intra-infrapatellar glucocorticoid versus intra-articular...

10.1136/bmjopen-2024-087785 article EN cc-by-nc-nd BMJ Open 2025-01-01

Postoperative sleep disturbance (PSD) is a common complication after spinal surgery that can be related to postsurgical pain, perioperative anxiety and depression. Recent studies have shown esketamine may improve surgery; however, it remains unclear whether intraoperative infusion of the postoperative quality patients undergoing surgery. This protocol for randomised, double-blinded, placebo-controlled clinical trial evaluate effect on PSD in Patients aged 18-65 years who plan undergo...

10.1136/bmjopen-2024-090089 article EN cc-by-nc BMJ Open 2025-03-01

Abstract As a promising immune checkpoint of immunogenic cell death (ICD) and multifunctional calcium‐binding molecular chaperone, calreticulin (CALR) has been attracting increasing attention. CALR mainly locates in cellular endoplasmic reticulum significantly affects proliferation, invasion, induction apoptosis, angiogenesis breast invasive carcinoma (BRCA). overexpression might be correlated with worse outcome. Nonetheless, it remains obscure how correlates infiltration survival prognosis...

10.1002/tox.24120 article EN Environmental Toxicology 2024-01-21
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