Zerrin Özköse

ORCID: 0000-0002-1623-1503
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Neurotoxicity Research
  • Intensive Care Unit Cognitive Disorders
  • Nausea and vomiting management
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Airway Management and Intubation Techniques
  • Pediatric Pain Management Techniques
  • Dental Anxiety and Anesthesia Techniques
  • Cardiac Arrest and Resuscitation
  • Hemostasis and retained surgical items
  • Spine and Intervertebral Disc Pathology
  • Spinal Hematomas and Complications
  • EEG and Brain-Computer Interfaces
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Structural Anomalies and Repair
  • Spinal Dysraphism and Malformations
  • Management of metastatic bone disease
  • Cerebrovascular and genetic disorders
  • Porphyrin Metabolism and Disorders
  • Spinal Cord Injury Research
  • Head and Neck Surgical Oncology
  • Occupational Health and Burnout
  • Thermoregulation and physiological responses

Gazi University
2006-2023

Gazi Hastanesi
2005-2023

Sağlık Bilimleri Üniversitesi
2022

Türk Anesteziyoloji ve Reanimasyon Derneği
2018

1 The aim of this retrospective study was to evaluate etiological and demographical characteristics acute adult poisoning patients during year at a university hospital in Ankara, Turkey. 2 Two-hundred twenty-eight adults (of which 180 were suicidal cases) admitted the emergency center with poisonings. This 0.7% all admissions. female-to-male ratio 3: 1, majority (63.6%) below age 25 years. 3 Drugs major cause 75.9% cases, followed by inhalation gases (17.6%), food (2.6%), corrosives (2.2%),...

10.1191/096032799678839446 article EN Human & Experimental Toxicology 1999-10-01

This study aimed to examine the effects of sevoflurane or isoflurane preconditioning on cerebral ischemia/reperfusion-induced inflammation, oxidative stress, and lipid peroxidation test hypothesis that underlining mechanism protective effect involves changes in apoptotic gene expression profiles an experimental model middle artery occlusion rats.Twenty-four adult male rats were randomly divided into 3 groups: control (n=8), (n=8). For preconditioning, these groups exposed 40% O2, 2%...

10.1097/ana.0b013e318266791e article EN Journal of Neurosurgical Anesthesiology 2012-08-07

The clinical effects, recovery characteristics, and costs of total intravenous anesthesia (TIVA), sevoflurane, isoflurane have been measured in various out-patient operations, but not evaluated patients undergoing laminectomy or discectomy. In the current study, authors assessed hemodynamic recovery, cost analyzes after discectomy comparing TIVA, anesthesia. Sixty American Society Anesthesiologists I II were randomly divided into three groups, each consisting 20 patients. Group received...

10.1097/00008506-200110000-00003 article EN Journal of Neurosurgical Anesthesiology 2001-10-01

The α2-agonist dexmedetomidine (Dex), a sedative and analgesic, reduces heart rate (HR) blood pressure, has been used in the practice of anesthesia. In this study, we aimed to evaluate effects Dex on hemodynamic variables, anesthetic sparing effects, recovery profiles patients who underwent surgery prone position. position itself can cause decrease systemic pressure. Forty undergo lumbar discectomy were randomly assigned receive either (a loading dose 1 μg/ kg 10 minutes followed by an...

10.1620/tjem.210.153 article EN The Tohoku Journal of Experimental Medicine 2006-01-01

Objective We compared the effects of sevoflurane and isoflurane on systemic inflammation, sepsis-associated encephalopathy, memory impairment in a rat sepsis model cecal ligation puncture (CLP)-induced polymicrobial peritonitis. Methods Twenty-four rats were assigned to sham, CLP, CLP + sevoflurane, groups. At 72 hours after underwent behavior tests. Serum cytokines evaluated. Brain tissue samples collected for determination glutathione peroxidase (GPX), superoxide dismutase (SOD), catalase;...

10.1177/0300060518773265 article EN cc-by-nc Journal of International Medical Research 2018-05-13

Alzheimer disease (AD) is one of the most common neurodegenerative diseases and prevalent form dementia. Some factors in development AD, age being best-known one, have been suggested; however, no causes found yet. The pathophysiology highly complex, current therapies are palliative, a cure still lacking. Adverse effects anesthetics elderly reported since 1950s; awareness this old problem has recently gained importance again. Whether exposure to surgery general anesthesia (GA) associated with...

10.3906/sag-1407-40 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2015-01-01

The hemodynamic effects of perioperative stressors, including preoperative patient anxiety, intraoperative local anesthetic/adrenaline infiltrations, and some painful interventions, have not been fully elucidated in plastic surgery procedures. present study was designed to determine the stressor events American Society Anesthesiologists class I patients undergoing rhinoplasty procedures under general anesthesia. included 50 healthy patients, 18 51 years age (mean age, 27 ± 7 years), who...

10.1097/01.prs.0000150153.16897.d2 article EN Plastic & Reconstructive Surgery 2005-02-01

AIM:The tethered cord syndrome refers to a variety of lesions that can cause the conus medullaris be low-lying or incapable movement within spinal canal.Permanent temporary neurological complications were reported following surgical release.In this report, peri-and postoperative results in cases with followed by multimodal intraoperative neurophysiological monitoring (MIONM) methods are presented.MATeRIAL and MeTHodS: An IONM system (Nicolet CR Endeavor) was used for during...

10.5137/1019-5149.jtn.3314-10.1 article EN Turkish Neurosurgery 2010-01-01

The negative effects of surgery and anesthesia on cognitive functions their relationships with many factors are well known. In the present study we aimed to investigate effect total intravenous (TIVA) method postoperative between young elderly patients scheduled undergo lumbar disk surgery. Materials methods: TIVA was applied 40 less than 65 years old (young, Group Y) => (old, O), whose Mini Mental State Examination (MMSE) results serum S-100 beta protein levels were compared preoperatively...

10.3906/sag-1311-29 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2015-01-01

There are limited data in the literature investigating effects of anesthetic agents on cardiac output used chest-knee position. The aim this study is to compare inhalation and total intravenous anesthesia patients undergoing lumbar discectomy Materials methods: Forty position were allocated 2 groups. first group (GrS, n = 20) received sevoflurane after thiopental induction, while second (GrP, propofol induction infusion. Heart rate (HR), mean arterial pressure (MAP), peripheral oxygen...

10.3906/sag-1303-23 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2014-01-01

We report a case involving surgical sponge retained following an aortic valve replacement. The was placed into the left ventricle to protect calcified debris from falling down ventricular cavity. However, forgotten and inside patient. identified by transesophageal echocardiography, which performed because of difficulty in weaning patient cardiopulmonary bypass.

10.1111/j.1540-8175.2006.00213.x article EN Echocardiography 2006-03-28

Background/aim: The optimal technique for airway management in patients with cervical pathology remains unclear. Intubating laryngeal mask devices such as LMA CTrach and Fastrach have not been compared spine (C-spine) movements the context of pathology. present study aimed to determine upper C-spine by radiography during intubation different well comparing duration success surgery.Materials methods: Sixty scheduled elective surgery were registered this prospective, randomized study. Patients...

10.3906/sag-1906-135 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2019-01-01

Abstract Levosimendan (LS) is a novel calcium sensitizer drug that enhances cardiac contractility without increasing myocardial oxygen consumption, and induces vasodilatation. Positive inotropic support routinely used for weaning from cardiopulmonary bypass circulation in patients with reduced left ventricular function. This case report represents the successful usage of LS after coronary artery surgery. infusion was started at sixth hour circulation. There dramatic increase output 20...

10.1111/j.1540-8191.2007.00359.x article EN Journal of Cardiac Surgery 2007-01-23
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