- Fusion materials and technologies
- Magnetic confinement fusion research
- Nuclear Materials and Properties
- Laser-induced spectroscopy and plasma
- Developmental Biology and Gene Regulation
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- IPv6, Mobility, Handover, Networks, Security
- Acute Myeloid Leukemia Research
- Cerebrovascular and genetic disorders
- Electric Vehicles and Infrastructure
- RNA modifications and cancer
- Green IT and Sustainability
- Evaluation and Optimization Models
- Cultural Heritage Materials Analysis
- Ion-surface interactions and analysis
- Nuclear reactor physics and engineering
- Ferroptosis and cancer prognosis
- Analytical chemistry methods development
- Advanced Battery Technologies Research
- Genetics and Neurodevelopmental Disorders
- Advanced Topics in Algebra
- RNA Interference and Gene Delivery
- graph theory and CDMA systems
Chinese Academy of Sciences
2010-2022
First Affiliated Hospital of Anhui Medical University
2022
Anhui Medical University
2022
Kunming Institute of Zoology
2022
Institute of Plasma Physics
2013-2021
Southwestern Institute of Physics
2016
University of Wisconsin–Madison
2007
Children's Hospital of Philadelphia
2003
Interplay among GATA transcription factors is an important determinant of cell fate during hematopoiesis. Although GATA-2 regulates hematopoietic stem function, mechanisms controlling expression are undefined. Of particular interest the repression , because sustained in and progenitor cells alters derepressed erythroid precursors lacking GATA-1, but underlying unknown. Using chromatin immunoprecipitation analysis, we show that GATA-1 binds a highly restricted upstream region ≈70-kb domain,...
A laser based method combined with spectroscopy, such as laser-induced breakdown spectroscopy (LIBS) and ablation (LIAS), is a promising technology for plasma-wall interaction studies. In this work, we report the development of in situ laser-based diagnostics (LIBS LIAS) assessment static dynamic fuel retention on first wall without removing tiles between during plasma discharges Experimental Advanced Superconducting Tokamak (EAST). The was measured after different conditioning methods daily...
The Notch signaling pathway modulates cell fate in diverse contexts, including vascular development. Notch4 is selectively expressed endothelium and regulates remodeling. signal-dependent transcription factor activator protein 1 (AP-1) activates endothelial cells, but other factors/signals that regulate are largely unknown. We demonstrate that, unlike the established transrepression mechanism which glucocorticoid receptor (GR) antagonizes AP-1, AP-1 GR synergistically activated cells....
Abstract Reactive astrogliosis usually bears some properties of neural progenitors. How injury triggers astrocyte dedifferentiation remains largely unclear. Here, we report that ischemia induces rapid up-regulation Wnt2 protein in apoptotic neurons and activation canonical Wnt signaling reactive astrocytes mice, primates human. Local delivery shRNA abolished the while over-expressing promoted progenitor marker expression neurogenesis. Both was compromised ischemic caspase-3 −/− cortex....
Objective: Head and neck squamous cell carcinoma (HNSCC) is a common heterogeneous cancer with complex carcinogenic factors. However, the current TNM staging criteria to judge its severity formulate treatment plans evaluate prognosis are particularly weak. Therefore, robust diagnostic model capable of accurately diagnosing predicting HNSCC should be established. Methods: Gene expression clinical data were retrieved from The Cancer Genome Atlas Expression Omnibus databases. Key prognostic...
An orderly charging strategy for electric vehicles based on TOPSIS to solve the problem that distribution transformers in old residential areas cannot meet collective needs of a large number is proposed. The management structure analyzed. probability travel characteristics considering users determined. algorithm proposed control priority queuing with goal maximizing demand satisfaction rate and minimizing standard deviation transformer load. results calculation examples show method this...
In recent years, with the rapid development of China's economy and continuous improvement capital market, corporate mergers acquisitions, asset restructuring other activities have become active.In face current active M & a how to reasonably accurately target enterprise pricing, key issues affecting activities.This paper summarizes related theory merger, analyzes value assessment in introduces main contents methods value, use case explain detail goal method, but also on evaluation results...