Photo-responsive biocompatible micelles were constructed from amphiphilic hyperbranched polyphosphate based polymer (denoted as HPHEEP-DNQ) and applied in the controlled release of coumarin 102. HPHEEP-DNQ was designed synthesized by modification hydrophilic (HPHEEP) with hydrophobic, light-responsive 2-diazo-1,2-naphthoquinone (DNQ) molecules. Dynamic light scattering (DLS) transmission electron microscopy (TEM) measurements revealed that can self-assemble into spherical an average diameter...

Biocompatible and biodegradable polymersomes are commonly self-assembled from amphiphilic diblock copolymers composed of hydrophilic poly(ethylene glycol) (PEG) or poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) segments hydrophobic polyester blocks, such as poly(lactic acid) (PLA) poly(ε-caprolactone) (PCL). Such have emerged promising delivery vehicles for pharmaceutical applications. Presented in this review summaries recent developments biocompatible polymersomes, including...

Abstract A novel photo and thermo double‐responsive block copolymer was developed to fabricate micelles reverse in aqueous solution. The synthesized by ATRP copolymerization of a spiropyran‐ containing methacrylate (SPMA) with di(ethylene glycol) methyl ether (DEGMMA). By facile control the irradiation solution temperature, PSPMA‐core PDEGMMA‐core can be obtained, respectively. thermo‐ photo‐responsive were used as smart polymeric nanocarriers for controlled encapsulation, triggered release,...

Foot plantar pressure monitoring and gait analysis are of great significant in footwear design, sport biomechanics, injury prevention, early warning disease. Flexible wearable smart insoles pave a feasible way for these application scenarios. However, the majority currently developed composed synthetic polymers (e.g., plastics, rubbers, etc.), leading to inevitable problems associated with air permeability, hygiene condition, biocompatibility, wearing comfort. Here, new paradigm natural...

Poly(ethylene oxide) (PEO) and poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) are biocompatible polymers that have delivered clinically proven benefits in various biomedical applications. Biocompatible polymer vesicles were prepared on basis of the inclusion complexation between α-cyclodextrins (α-CDs) double-hydrophilic poly(ethylene oxide)-b-poly(2-methacryloyloxyethyl (PEO-b-PMPC) aqueous media without using organic solvent. The supramolecular structure nano-sized was demonstrated...

An azobenzene-containing block copolymer poly(ethylene oxide)-b-poly(6-[4-phenylazo phenoxy]hexyl methacrylate-co-2-(dimethylamino)ethyl methacrylate) (PEO-b-P(AzoMA-co-DMAEMA)) was successfully designed to explore self-assembly behavior in an aqueous solution. PEO-b-P(AzoMA-co-DMAEMA) can self-assemble into vesicles water. The morphologies and sizes of the be controlled by copolymerization hydrophobic AzoMA with different amounts DMAEMA. Spherical vesicle-to-compound vesicle-to-irregular...

Leather with durable and broad-spectrum antimicrobial properties is very attractive in applications to produce diabetic shoes. In this work, gallic acid stabilized silver nanoparticles (GA@AgNPs) were prepared as water-borne finishing agent be spray-coated on leather surface, subsequent immobilization onto skin collagen via chromium(III) cross-linking. Such chemical anchoring of AgNPs microscaled fibers not only enhanced the hydrophobicity surface but also converted ζ-potential from a...

Abstract A novel comb‐like derivative CPEG‐ g ‐DNQ was prepared by incorporating light responsive 2‐diazo‐1,2‐naphthoquinone (DNQ) groups into the structure of poly(ethylene glycol) (CPEG). DLS and TEM results showed that self‐assembled spherical micelles with an average size about 135 nm in water. Upon exposure to light, could be disrupted because conversion hydrophobic DNQ hydrophilic 3‐indenecarboylic acid. Additionally, coumarin 102 successfully loaded photo‐induced ON‐OFF release...

In this work, pH-sensitive and chromium-loaded mineralized nanoparticles (Cr-PPA NPs) were developed by self-assembly of poly (poly(ethylene glycol) methyl ether acrylate-co-acrylic acid) (poly(PEG-co-AA)) copolymers templated Cr(OH)3 mineralization. The Cr-PPA NPs exhibit excellent colloidal stability in water with high salt concentration, protein, pH above 3.0. As a novel chrome tanning agent, such could effectively protect deliver chromium into pickled pelt without reacting collagen...

ABSTRACT In this work, poly(ethylene glcycol)‐grafted chitosan (PEG‐ g ‐CS) was synthesized by conjugating PEG to the (CS) backbone. Such PEGylated CS copolymer further characterized FTIR and 1 H NMR, results demonstrated successful synthesis. After PEGylation, water solubility of significantly improved due hydrophilicity polymer. Therefore, prepared as borne coating for leather surface. The morphology on studied SEM contact angle measurement. Furthermore, antimicrobial activity investigated...

Abstract It has been a research goal to develop macroscopic materials with an optimized surface structure affix silver nanoparticles which could contaminate water and maximize their practical functions. Cellulose paper is versatile biomass material valued for its abundance, low cost, biocompatibility, natural composition. Until now, potential application in purification not adequately explored. In this study, gallic acid-modified (GA@AgNPs) were loaded onto commercial cellulose filter using...

A novel amphiphilic copolymer, poly (ethylene glycol)-graft-polyethyleneimine/amide (PEG-g-PEI/amide), is synthesized by grafting PEG and1,2-cis-Cyclohexanedicarboxylic anhydride onto the PEI. PEGylated polymeric micelles can be assembled from copolymers with well-defined nano-sizes, and anti-cancer drugs are successfully loaded into micelle core formed amide. The amides neighboring carboxylic acid groups exhibit pH-dependent hydrolysis reversibly shield cationic charge of amine on PEI,...

The clinical treatment of wounds with medical cotton gauze often encounters inflammation and excessive immune response triggered by bacterial infections, which can significantly prolong the wound healing process. It is, therefore, great significance to develop functional gauzes broad-spectrum antibacterial anti-inflammatory activities. Herein, we report a convenient, robust, practical strategy functionalize covalently immobilizing plant-derived gallic acids. obtained GA@Gauze exhibits not...

Abstract Well‐defined amphiphilic PLA ‐b‐ PMPC diblock copolymers were synthesized. Bimimetic micelles prepared and applied for release of anti‐cancer drugs (DOX). TEM DLS analysis revealed a regular spherical shape with small diameter (less than 50 nm) the micelle. The biocompatibility was studied, it found that possessed excellent cytocompatibility due to zwitterionic phosphorylcholine group. DOX could be efficiently loaded into loading efficiency 44–67%. DOX‐loaded showed lower...