- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and healthcare impacts
- Colorectal Cancer Surgical Treatments
- Dermatologic Treatments and Research
- Hernia repair and management
- Vascular anomalies and interventions
- Congenital Anomalies and Fetal Surgery
- Tryptophan and brain disorders
- Parasitic infections in humans and animals
- Nitric Oxide and Endothelin Effects
- Wound Healing and Treatments
- Alcoholism and Thiamine Deficiency
- Diabetic Foot Ulcer Assessment and Management
- Renal and Vascular Pathologies
- Radiomics and Machine Learning in Medical Imaging
- Surgical site infection prevention
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Vitamin D Research Studies
- Peripheral Artery Disease Management
- Testicular diseases and treatments
- Body Contouring and Surgery
- Helicobacter pylori-related gastroenterology studies
Victor Babeș University of Medicine and Pharmacy Timișoara
2014-2025
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara
2010-2025
Clinical Emergency Hospital Bucharest
2021-2023
West University of Timişoara
2019
National Institute of Research and Development for Electrochemistry and Condensed
2013-2015
Spitalul Clinic Dr. Victor Babes
2004
Venous leg ulcers (VLUs) are a common chronic wound condition susceptible to infection by various bacterial species. Understanding presence and antibiotic sensitivity is crucial for effective treatment. Methodsː Medical records of 60 patients diagnosed with the C6 venous insufficiency stage were analyzed retrospectively. The divided into an active recurrent VLU group (33 cases) first-onset (27 cases). Bacterial identification, sensitivity, laboratory markers assessed. Resultsː
Scop: Analiza comparativă a cryostripping-ului în raport cu safenectomia convenţională.Materiale şi Metode: Studiul inclus 2191 pacienţi dispensarizaţi Compartimentul de Flebologie din cadrul Clinicii I Chirurgie SCJUT, perioada septembrie 2013 -aprilie 2023, l-a care s-a practicat prin cryostripping (1327 pacienţi) sau pe cale convenţională (864 pacienţi).Am analizat comparativ durata costurile intervenţiei, spitalizare, rezultatele postoperatorii, fezabilitatea metodei, precum avantajele...
Background Colorectal cancer is considered to be triggered by the malignant transformation of colorectal polyps. Early diagnosis and excision polyps has been found lower mortality morbidity associated with cancer. Objective The aim this study offer a predictive model for presence based on Random Forests machine learning algorithm, using basic patient information common laboratory test results. Materials methods 164 patients were included in study. following data was collected: sex,...
Background/Objectives: Artificial intelligence (AI) is rapidly transforming the landscape of modern medicine, offering advanced tools for diagnosing complex conditions. In realm venous pathologies such as chronic disease (CVD), reflux, and deep thrombosis (DVT), AI has shown tremendous potential to improve diagnostic accuracy, streamline workflows, enhance clinical decision-making. This study aims evaluate efficacy feasibility algorithms in diseases explore their impact on practice. Methods:...
In light of the elevated incidence and consequential prognostic implications associated with colorectal cancer, a comprehensive investigation into impact exerted by inflammatory status on patient management becomes imperative. A retrospective study spanning 7 years was conducted, involving collection data cancer patients undergoing surgical intervention. We evaluated six inflammation ratios derived from complete peripheral blood counts. thorough analysis these markers’ capacity revealing...
Obesity is an important preventable risk factor for morbidity and mortality from cardiometabolic disease. Oxidative stress (including in visceral adipose tissue) chronic low-grade inflammation are the major underlying pathomechanisms. Monoamine oxidase (MAO) has recently emerged as source of cardiovascular oxidative stress. The present study was conducted to evaluate role MAO contributor reactive oxygen species (ROS) production white tissue vessels harvested patients undergoing elective...
Objective: The presentation of cryostripping as an alternative procedure useful in venous insufficiency treatment. Methods: This retrospective study presents the results 1087 operated patients, including follow-ups. Cryostripping was practised all mentioned cases. Patient follow-up performed at one week, month, and six months postoperatively by clinical examination, Doppler ultrasonography, CIVIQ-20 r-VCSS questionnaires. Outcomes, complications, surgery hospitalisation period, benefits...
Cystic echinococcosis (CE) is a neglected parasitic disease caused by the tapeworm Echinococcus granulosus. The aim of this study was to assess epidemiological features human cystic in patients from Western Romania. We retrospectively investigated medical records hospitalized with CE between 1 January 2007 and September 2022. A total 366 (range 18-90 years) were recorded. number individuals higher aged 50-59 years (83/366, 22.7%), females (194/366, 53%), residents rural areas (225/366,...
Obesity is an age-independent, lifestyle-triggered, pandemic disease associated with both endothelial and visceral adipose tissue (VAT) dysfunction leading to cardiometabolic complications mediated via increased oxidative stress persistent chronic inflammation. The purpose of the present study was assess in VAT vascular samples effect vitro administration vitamin D. mesenteric artery branches were harvested during abdominal surgery performed on patients referred for general (n = 30) that...
The aim of this study was to quantify the impact COVID-19 pandemic on surgical treatment patients with gastric cancer. Data from undergoing surgery for cancer during were analyzed and results obtained compared corresponding periods 2016–2017 2018–2019. Various parameters taken into consideration their dynamics highlight significant changes in year two pre-pandemic periods. Statistical analysis revealed a marked decrease number surgeries performed (p < 0.001). Severe prognostic factors...
Chronic venous disease (CVD) represents a significant health challenge, particularly in obese individuals. This study focuses on the interplay between inflammation, obesity, and CVD, by analyzing role of inflammatory markers progression.
The influence of excipients on the stability sodium levothyroxine pentahydrate (LTSS) under ambient conditions and thermal stress was evaluated. Since LTSS is a synthetic hormone with narrow therapeutic index, interactions can lead to drastic diminution activity. Ten commonly used pharmaceutical different roles in solid formulations were chosen as components for binary mixtures containing LTSS, namely, starch, anhydrous lactose, D-mannitol, D-sorbitol, gelatin, calcium lactate pentahydrate,...
Oxidative stress and vascular inflammation are the two major pathomechanisms that contribute to progression of both cardiovascular metabolic diseases.We have previously demonstrated monoamine oxidases (MAOs), mitochondrial enzymes with isoforms (A B), contributors endothelial dysfunction associated in mice.The present study was purported assess effects MAOs on rats lipopolysaccharide (LPS)-induced acute inflammation.To this aim, aortas harvested from treated or not a single dose LPS were...
Chronic venous disease (CVD) is a frequently encountered that progresses with age. Although the principal method of evaluation and diagnosis Doppler ultrasound, routine laboratory tests may be an easier more accessible way to evaluate CVD progression. The present retrospective study evaluated results 256 patients diagnosed CVD. According Clinical, Etiological, Anatomical Pathophysiological classification, depending on stage, were stratified into three groups: Group 1 (C2-C3; mild disease), 2...
The aim of this study was to highlight the changes in surgical treatment patients with thyroid pathology over a 4-year period. dynamics various parameters during period at tertiary University Hospital Timisoara, Romania were examined. Data from 1339 who underwent surgery between 26 February 2019 and 25 2023 analyzed. divided into four groups: Pre-COVID-19, C1 (first year pandemic), C2 (second year), C3 (third year). Multiple Statistical analysis revealed significant decrease number...
Gastric cancer ranks as the fifth most common cancer, and assessment of inflammatory biomarkers in these patients holds significant promise predicting prognosis. Therefore, data from undergoing surgical intervention for gastric over a 7-year period were analyzed. This study was retrospective involved preoperative investigation six parameters derived complete blood counts. Statistical analysis revealed increase leucocyte-to-monocyte ratio (LMR) (