A5019150525- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Colorectal Cancer Treatments and Studies
- Gestational Trophoblastic Disease Studies
- Ovarian cancer diagnosis and treatment
- Acute Lymphoblastic Leukemia research
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Health and Risk Factors
- Lung Cancer Research Studies
- Maternal and fetal healthcare
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Global Public Health Policies and Epidemiology
- Chronic Myeloid Leukemia Treatments
- Cancer Diagnosis and Treatment
HOPE Clinic
2024-2025
Instituto Nacional de Enfermedades Neoplásicas
2021-2024
Universidad Privada San Juan Bautista
2022
Despite osimertinib being the standard therapy for advanced EGFR T790M mutation positive NSCLC, in many Latin American countries, access to molecular testing and targeted therapies is limited, directly impacting patient outcomes. This study describes real-world management outcomes of Peruvian patients with EGFR-mutated NSCLC who develop mutation. We conducted a multicenter retrospective including from nine institutions, both public private, progressed first-line TKI developed mutation,...
e23308 Background: Epithelial Ovarian Cancer (EOC) is an heterogenous disease which usually diagnosed inadvanced stages. Despite the advent of new therapies, outcomes for this remain poor in certain scenarios. We describe clinical features and survival a developing country. Methods: Retrospective study based on case review women with newly EOC between 2015 2017 at Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima- Peru. Descriptive analysis was conducted characteristics,...
Despite the advances in management of advanced non-small cell lung cancer (NSCLC), access to genetic profiling and target therapies remains a challenge Latin America, even countries with higher rate targetable mutations. The aim this study is evaluate clinical outcomes anti-epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) treatment Peruvian real-world setting.This retrospective recurrent or NSCLC EGFR mutated patients diagnosed treated anti-EGFR TKI at Instituto...
e20605 Background: Osimertinib is the standard of care for advanced NSCLC patients with EGFR T790M-positive whose disease has progressed to TKI therapy, however, knowledge on real benefit these therapies in Latin American setting remains unclear due lack access most countries. The aim this study evaluate outcomes as sencond line treatment a real-world Peruvian setting. Methods: This retrospective treated osimertinib at seven institutions between July 2018 and May 2023. Outcomes were...
Background: Gestational trophoblastic neoplasia (GTN) is a rare tumor with an excellent prognosis. This study aimed to refine the FIGO risk score by incorporating immune nutritional factors. Methods: A retrospective analysis was conducted on women diagnosed GTN between 2005 and 2019 who received chemotherapy (CT). Statistical tests (Wilcoxon, univariate, multivariate analyses) were used assess associations response CT, Cox regression models applied identify factors influencing overall...
e17529 Background: Cervical cancer is a global public health problem, with higher impact in many low-income and middle income countries. In Peru, cervical the leading cause of deaths among women. The aim this study to investigate prognostic factors affecting long-term survival locally advanced young patients treated concurrent chemoradiotherapy. Methods: This retrospective women who underwent radiotherapy platinum-based chemotherapy at national peruvian institute (INEN), from 2008 2012....
Abstract Background: Worlwide lung cancer is the leading cause of related death. Research has revealed significant socioeconomic disparities in cancer; generally people from lower socio-economic status exhibit higher incidence and poorer survival. . Data on how influence Latin America scarce. We evaluated association economic income with Peru's capital city. Methods: This a retrospective ecologic study newly diagnosed between two periods 2010-2012 2013-2015 reported Lima metropolitan Cancer...
e17529 Background: Gestational trophoblastic neoplasia (GTN) is a rare tumor with an excellent prognosis. With the advent of multiagent chemotherapy, cure rate improved to nearly 100% in low-risk group (LR). However, developing countries it lower, especially high risk (HR) group. Herein, we describe our experience management and survival GTN over 14y period. Methods: Retrospective study based on case review women newly diagnosed between 2005 2019 at Instituto Nacional de Enfermedades...
e15027 Background: The optimal treatment of advanced NSCLC patients is currently led by genomic profiling with the goal detecting actionable mutations an approved targeted therapy. However, tissue DNA samples are not always available to perform this assays. In context, liquid biopsy has emerged as a valuable tool for providing best option. Methods: Retrospective study held at Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima - Peru, between January 2019 and September 2021 assess...
Introducción: la evidencia mundial demuestra que en el CPCNP metastásico con una mutación sensibilizante de EGFR, los inhibidores EGFR son superiores a quimioterapia citotóxica tratamiento primera línea, sin embargo, algunos países como Perú y Colombia hay un acceso limitado las pruebas moleculares para definir inicio estas terapias dirigidas. En este escenario, es frecuente oncólogos inicien hasta estén disponibles resultados prueba EGFR. No datos del mundo real medir impacto comportamiento...