Rossana Ruiz

ORCID: 0000-0001-5199-6686
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Lung Cancer Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Global Cancer Incidence and Screening
  • Breast Cancer Treatment Studies
  • Economic and Financial Impacts of Cancer
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Treatments and Studies
  • Cervical Cancer and HPV Research
  • Multiple and Secondary Primary Cancers
  • Ovarian cancer diagnosis and treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Genetic factors in colorectal cancer
  • Cancer Diagnosis and Treatment
  • Advanced Breast Cancer Therapies
  • Myasthenia Gravis and Thymoma
  • COVID-19 and healthcare impacts
  • Pituitary Gland Disorders and Treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Endometrial and Cervical Cancer Treatments
  • Global Public Health Policies and Epidemiology
  • Gestational Trophoblastic Disease Studies
  • Cancer survivorship and care

Instituto Nacional de Enfermedades Neoplásicas
2016-2025

Universidad Peruana Cayetano Heredia
2015-2025

Universidad Científica del Sur
2019-2024

EsSALUD
2018-2024

Universidad Privada San Juan Bautista
2022-2023

Hospital Militar Central
2019

Universidad Ricardo Palma
2019

Universidad de San Martín de Porres
2019

The University of Texas MD Anderson Cancer Center
2019

Massachusetts General Hospital
2016-2017

BackgroundThere are well-known differences in gender outcome non-small cell lung cancer (NSCLC) and other cancers. In this work, we evaluated several randomised clinical trials to explore the influence of patients with NSCLC treated targeted therapy immunotherapy.MethodsWe performed a series meta-analysis compare routine setting for overall survival progression-free (PFS) phase III comparing EGFR inhibitors versus chemotherapy (OPTIMAL, LUX-lung 3, 6, EURTAC, ENSURE WTJOG); ALK (ASCEND 4,...

10.1136/esmoopen-2018-000344 article EN cc-by-nc ESMO Open 2018-01-01

Background To compare survival outcomes of patients with advanced or metastatic non‐small cell lung cancer (NSCLC) who received immunotherapy as first‐, second‐ beyond line, versus matched receiving standard chemotherapy special characterization hyperprogressors. Methods A retrospective cohort study 296 unresectable/metastatic NSCLC treated either, second‐, third‐ fourth‐line was conducted. comparison a historical first‐line and random forest tree analysis to characterize hyperprogressors...

10.1111/1759-7714.13272 article EN cc-by Thoracic Cancer 2019-12-12

Despite osimertinib being the standard therapy for advanced EGFR T790M mutation positive NSCLC, in many Latin American countries, access to molecular testing and targeted therapies is limited, directly impacting patient outcomes. This study describes real-world management outcomes of Peruvian patients with EGFR-mutated NSCLC who develop mutation. We conducted a multicenter retrospective including from nine institutions, both public private, progressed first-line TKI developed mutation,...

10.1016/j.ctarc.2025.100906 article EN cc-by Cancer Treatment and Research Communications 2025-03-01

An in silico pathway analysis was performed an attempt to identify new biomarkers for cervical carcinoma.Three publicly available Affymetrix gene expression data sets (GSE5787, GSE7803, GSE9750) were retrieved, vouching a total 9 cancer cell lines, 39 normal samples, 7 CIN3 samples and 111 samples. Agilent set (GSE7410; 5 35 from invasive cancer) selected as validation set. Predication of microarrays the biomarkers. We compared lists differentially expressed genes between on one hand...

10.1136/esmoopen-2018-000352 article EN cc-by-nc ESMO Open 2018-01-01

To confirm that patients affected by colorectal cancer have the V2 region of Septin 9 (SEPT9) gene hypermethylated in circulating free DNA from a peripheral blood sample before surgery and to determine if this disappears after complete resection tumour.Plasma 10 with was collected preoperative three months surgery. The analysis methylation status promoter SEPT9 performed using 7500 Fast Real-Time PCR System.Hypermethylation detected 8 out samples (one negative result probed be Lynch...

10.1155/2020/9761406 article EN Disease Markers 2020-06-05

e23308 Background: Epithelial Ovarian Cancer (EOC) is an heterogenous disease which usually diagnosed inadvanced stages. Despite the advent of new therapies, outcomes for this remain poor in certain scenarios. We describe clinical features and survival a developing country. Methods: Retrospective study based on case review women with newly EOC between 2015 2017 at Instituto Nacional de Enfermedades Neoplasicas (INEN), Lima- Peru. Descriptive analysis was conducted characteristics,...

10.1200/jco.2024.42.16_suppl.e23308 article EN Journal of Clinical Oncology 2024-06-01

Prostate, breast, colorectal, cervical, and lung cancers are the leading cause of cancer in Latin America Caribbean (LAC) accounting for nearly 50% cases deaths region. Following IARC Code Against Cancer methodology, a group American experts evaluated evidence on several medical interventions to reduce incidence mortality considering burden A recommendation limit use HRT was issued based risk associated develop endometrial, ovarian growing concerns related over-the-counter without...

10.1016/j.canep.2023.102446 article EN cc-by Cancer Epidemiology 2023-10-01

To determine the clinical and histological characteristics prognostic factors of cervical cancer (CC) in young Peruvian patients.Retrospective analysis patients younger than 35 years old diagnosed with CC between 2008 2012 Instituto Nacional de Enfermedades Neoplásicas.449 had epithelial neoplasms. The main types were: squamous cell carcinoma (84.9%), adenocarcinoma (11.0%) adenosquamous (2.4%). average tumor size was 4.98 cm. Anemia (55.7%), elevated creatinine (21.2%) hydronephrosis...

10.17843/rpmesp.2017.342.2653 article ES cc-by-nc Revista Peruana de Medicina Experimental y Salud Pública 2017-06-30

Background: The COVID-19 pandemic caused discontinuities in cancer care (CC) most countries. Here, the authors describe real-world impacts of implementing a contingency plan employing telemedicine for CC. Methods: A retrospective study patients who received CC through at Instituto Nacional de Enfermedades Neoplasicas, Peru, from March 2020 to February 2021 was conducted. Impacts were measured by comparing amount administered during versus prior year. Results: total 16,456 visits carried out....

10.2217/fon-2022-0239 article EN Future Oncology 2022-10-01

The advent of immunotherapy has revolutionized the treatment advanced non-small cell lung cancer (NSCLC), improving prognosis this disease and becoming a key part treatment, especially in population without an oncogenic driver mutation. Two different groups immune checkpoint inhibitors (ICIs) are used cancer: Anti- Cytotoxic T-lymphocyte antigen-4 (Anti-CTLA 4) T-cell receptor programmed death-1 or its ligand (Anti-PD-1 Anti PD-L1). Here in, we review uptodate on use for NSCLC.

10.20944/preprints202307.1242.v1 preprint EN 2023-07-19
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