A5100313845- Insect symbiosis and bacterial influences
- Quantum Dots Synthesis And Properties
- Insect-Plant Interactions and Control
- Lymphoma Diagnosis and Treatment
- Plant Virus Research Studies
- Genomics and Phylogenetic Studies
- Advanced Wireless Communication Technologies
- Chronic Lymphocytic Leukemia Research
- Insect and Pesticide Research
- Acute Lymphoblastic Leukemia research
- Insect Resistance and Genetics
- Land Use and Ecosystem Services
- Case Reports on Hematomas
- Optical Wireless Communication Technologies
- Chronic Myeloid Leukemia Treatments
- Gastric Cancer Management and Outcomes
- Alcohol Consumption and Health Effects
- Bacteriophages and microbial interactions
- Inflammatory Biomarkers in Disease Prognosis
- Acute Myeloid Leukemia Research
- Nematode management and characterization studies
- Energy, Environment, Economic Growth
- Gout, Hyperuricemia, Uric Acid
- Aquaculture Nutrition and Growth
- Blood Pressure and Hypertension Studies
The University of Melbourne
2025
Sichuan Academy of Agricultural Sciences
2022-2025
Institute of Plant Protection
2013-2025
First Affiliated Hospital Zhejiang University
2024-2025
Research Center for Eco-Environmental Sciences
2023-2024
Beijing Institute of Technology
2024
Hebei North University
2023-2024
Chinese Academy of Agricultural Sciences
2013-2024
Chinese Academy of Sciences
2023-2024
Third Affiliated Hospital of Southern Medical University
2023-2024
• MDD has substantial changes in the structure and function of gut microbiota. exhibited decreased amino acids bile increased lipids blood. The blood immune cell subtypes tend to promote inflammation. could be divided into two subtypes, one is correlated with relapse. We revealed integrative discriminative signatures for distinguishing from HC. Major depressive disorder (MDD) involves systemic peripheral microbiota, but current understanding incomplete. Herein, we conducted a multi-omics...
Pacific Biosciences (PacBio) HiFi sequencing technology generates long reads (>10 kbp) with very high accuracy (<0.01% error). Although several de novo assembly tools are available for reads, there no comprehensive studies on the evaluation of these assemblers. We evaluated performance 11 assemblers (1) real data three eukaryotic genomes; (2) 34 synthetic sets different ploidy, coverage levels, heterozygosity rates, and error rates; (3) one metagenomic set; (4) five composition...
The green peach aphid, Myzus persicae, is globally distributed and an important pest of many economically valuable food crops, largely due to its ability transmit plant viruses. Almost all aphids, including M. carry the obligate symbiont Buchnera aphidicola, which provides essential amino acids that aphids cannot obtain from phloem plants themselves. Many also harbor facultative (secondary) endosymbionts, provide benefits under specific ecological conditions. In this study, we screened for...
Summary A chemotherapy‐based mobilization regimen in patients who mobilize poorly, based on etoposide, cytarabine and pegfilgrastim (EAP), has recently been introduced. The aim of this prospective study was to investigate the efficacy safety EAP with poorly mobilizing multiple myeloma (MM) or lymphoma. This single‐arm clinical trial performed at eight public hospitals China registered as a (NCT05510089). inclusion criteria were; (1) diagnosis MM lymphoma, (2) defined ‘poor mobilizer’ (3)...
This paper first prepared a water-based magnetic fluid using chemical co-precipitation method and conducted detailed characterization calculation of its important magnetization properties. Key parameters for analyzing the influence mechanism on rheological properties were obtained. Subsequently, impact different field shear rates magnetoviscous effect, shear-thinning behavior, yield stress was studied through steady rotation measurements. The results showed positive correlation between...
Epstein-Barr virus (EBV)-positive nodal T-cell and NK-cell lymphoma is a rare neoplasm of cytotoxic or lineage. Here, we report 26 cases affecting 14 men 12 women with median age 52 years. All patients presented disease involving multiple lymph nodes, 20 22 (91%) fully staged had advanced Ann Arbor stage disease. Spleen, liver, bone marrow were involved in 70%, 50%, 52% cases, respectively. These dismal prognosis survival 30 days. Histologically, nodes replaced by diffuse pattern. Lymphoma...
The bird cherry-oat aphid, Rhopalosiphum padi, is a major pest of agriculture due to its ability directly damage crops and transmit plant viruses. As industries move away from chemical control, there interest in exploring new options suppress the impact this pest. We describe production transinfected line R. padi carrying bacterial endosymbiont, Regiella insecticola, originating green peach Myzus persicae. show that increases fitness novel host despite decreasing native host. also shows low...
Abstract Background: JMT601 is a bi-specific left-right asymmetrical fusion protein comprised of high CD20 binding affinity Fab arm and low CD47 fragment SIRPα, without CD20-negative lymphoma cells, RBCs platelet. was more effective in multiple human B-cell models than conventional CD20-targeted antibodies monotherapy combination with but severe anemia thrombocytopenia. Here we present the preliminary safety efficacy patients relapse/refractory positive NHL. Methods: Patients aged 18-70...
e15010 Background: Bispecific ADCs (BsADCs) enhance efficacy, reduce toxicity, and overcome drug resistance by increasing internalization tumor specificity. EGFR c-MET are frequently co-expressed in various solid tumors, including non-small cell lung cancer (NSCLC), small (SCLC), colorectal (CRC), head neck cancer, etc. DM005 is a BsADC conjugated to BLD1102 (linker/DNA topoisomerase I inhibitor BCPT02), targeting with an average drug-to-antibody ratio (DAR) of 4. Preclinical studies shows...
Lung cancer, especially lung squamous cell carcinoma (LUSC), is one of the most common malignant tumors worldwide. Currently, radiosensitization research a vital direction for improvement LUSC therapy. Long non-coding RNAs (lncRNAs) can be novel biomarkers due to their multiple functions in cancers. However, function and mechanism lncRNA KCNQ1OT1 radioresistance remain elucidated.The clonogenic assay was employed determine SK-MES-1R NCI-H226R cells. Real-time quantitative polymerase chain...
Abstract Aphelenchoides besseyi is a seed-borne plant-parasitic nematode that causes severe rice yield losses worldwide. In the present study, A. Anhui-1 strain isolated from in China was sequenced with hybrid method combining PacBio long reads and Illumina short reads, subsequently annotated using available transcriptome references. The genome assembly consists of 166 scaffolds totaling 50.3 Mb, an N50 1.262 Mb maximum scaffold length 9.17 Mb. A total 16,343 genes were genome, 94 gene...
Cytoplasmic incompatibility (CI) is the most common phenotype induced by endosymbiont Wolbachia and results in embryonic lethality when Wolbachia-modified sperm fertilize eggs without Wolbachia. However, carrying same strain of can rescue this death, thus producing viable Wolbachia-infected offspring. Hence be transmitted mainly hosts' eggs. One models explaining CI "titration-restitution", which hypothesized that titrated-out some factors from egg would restitute after fertilization. how...
Abstract The CACA Guidelines was summarized by Hematology Oncology Committee of China Anti- Cancer Association. This portion the for adult acute myeloid leukemia (AML) not only focuses on diagnosis, treatment options younger (age < 60 years) and older ≥ patients (including non-APL, APL, R/R AML), but also pay attention to AML complications, including central nervous system (CNSL), cardiotoxicity, agranulocytosis fever, hepatitis B virus reactivation, uric acid nephropathy, bleeding...
Sitobion miscanthi, an important viral vector of barley yellow dwarf virus (BYDV), is also symbiotically associated with endosymbionts, but little known about the interactions between aphid and BYDV. Therefore, two aphids' geographic populations, differing in their BYDV transmission efficiency, after characterizing were treated antibiotics to investigate how changes composition endosymbiont population affected efficiency. After antibiotic treatment, Rickettsia was eliminated from...