A5026800056- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Acute Kidney Injury Research
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Iron Metabolism and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Ischemia and Reperfusion
- Neonatal Respiratory Health Research
- Metabolomics and Mass Spectrometry Studies
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Congenital Anomalies and Fetal Surgery
- Advanced MEMS and NEMS Technologies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cancer, Hypoxia, and Metabolism
- Congenital Diaphragmatic Hernia Studies
- Central Venous Catheters and Hemodialysis
- Erythropoietin and Anemia Treatment
- Extracellular vesicles in disease
- Aortic aneurysm repair treatments
- Pharmacological Effects and Toxicity Studies
- Heart Failure Treatment and Management
- Hemoglobinopathies and Related Disorders
Xiamen University
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2021
Guangdong Institute of Intelligent Manufacturing
2021
Peking Union Medical College Hospital
2019
Objective To evaluate the anesthetic effects and safety of ciprofol combined with low-dose alfentanil in sedation patients during Transesophageal Echocardiography (TEE).
Abstract Background The ischemia–reperfusion (IR) environment during deep hypothermic circulatory arrest (DHCA) cardiovascular surgery is a major cause of acute kidney injury (AKI), which lacks preventive measure and treatment. It was reported that cold inducible RNA-binding protein (CIRP) can be induced under hypoxic stress may have protective effect on multiple organs. purpose this study to investigate whether CIRP could exert renoprotective IR the potential mechanisms. Methods Utilizing...
Mortality and morbidity of children received veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support after cardiac surgery remain high despite remarkable advances in medical management devices. The purpose this study was to describe outcomes risk factors applying VA-ECMO the surgical pediatric population. We retrospectively analyzed 85 consecutive patients (aged <18 years) who postcardiotomy from January 2010 December 2018. Median (IQR) age at ECMO implantation cohort 12.7 (6.4,...
Background: Chylothorax is a severe complication after total cavopulmonary connection (TCPC) in children. This study was performed to evaluate the incidence, risk factors, and short- long-term prognosis for chylothorax. Methods: We retrospectively reviewed electronic records of patients who underwent TCPC between January 2008 December 2020 Fuwai Hospital. Patients were divided into two groups based on occurrence post-operative Univariate multivariate analyses identify survival estimated by...
Objective: Serum ferritin has been identified as a prognostic marker in patients with variety of diseases. In the present study we aim to determine prevalence risk factors and outcomes for hyperferritinemia children undergoing cardiac surgery cardiopulmonary bypass congenital heart defects. Methods: The serum levels 457 between ages twentyeight days three years June 1, 2017 2018 were analyzed. early postoperative was investigated; defined level ≥250 ng/ml. Multivariable regression models...
Simple regional cerebral perfusion (SRCP) or cerebro-myocardial (CMP) is selectively used in one-stage complex aortic arch malformation repair. This analysis was performed to investigate the effect of CMP and SRCP on perioperative blood product consumption, evaluate whether these two strategies have different effects clinical outcomes. A retrospective 284 children with complicated from January 2010 June 2018 performed. The overall cohort divided into group (n = 202) 82). comprehensive...
Histidine-tryptophan-ketoglutarate (HTK) is a solution commonly used for organ transplantation. However, there no certified fixed regimen on-pump heart surgery in neonates. We aimed to retrospectively evaluate the outcomes related different HTK dosages and analyze safety of high-dosage perfusion.A total 146 neonates who underwent with single-shot perfusion were divided into two groups according dosages: standard-dose (SD) group (n = 63, 40 mL/kg < ≤ 60 mL/kg) high-dose (HD) 83, >60 mL/kg)....
Abstract Objective Cardiac surgery associated-acute kidney injury (CS-AKI) occurs in 40–55% of patients undergoing for repair acute type A aortic dissection (ATAAD). Few studies have investigated the association postoperative AKI with dysfunction seen long-term after surgical ATAAD. The aim our study was to identify risk factors developing post-ATAAD chronic disease (CKD) at 6 months. Methods We retrospectively reviewed a contemporary cohort all who underwent ATAAD from January 1, 2020...
Abstract Objective Cardiopulmonary bypass-associated acute kidney injury (CPB-AKI) is a frequent complication after cardiac surgery in children patients. Intraoperative hybrid (IPH) new technique which needed contrast administration. Contrast was also reported to induce AKI. Therefore, we hypothesized that the IPH would increase occurrence of CPB-AKI Congenital heart disease Methods A total 1509 consecutive patients (age≤3 year) undergoing on-pump were enrolled this study from November, 2017...
Many measures have been proposed for myocardial protection in pediatric congenital heart surgeries, but little data is available China. This study investigates strategies cardiopulmonary bypass (CPB) throughout Online questionnaires were delivered to 100 hospitals 27 provinces. The number of yearly on-pump cardiovascular surgeries these varied greatly. About 91.0% respondents believe that each surgery should at least two perfusionists, while only 64.0% actually met this requirement. For...