Anna Witkowska

ORCID: 0000-0002-1642-2342
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Research Areas
  • Inflammatory Biomarkers in Disease Prognosis
  • Cardiac Structural Anomalies and Repair
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac and Coronary Surgery Techniques
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Hepatitis C virus research
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Valve Diseases and Treatments
  • Coronary Interventions and Diagnostics
  • Inflammasome and immune disorders
  • Cardiac Imaging and Diagnostics
  • Cardiac pacing and defibrillation studies
  • Circadian rhythm and melatonin
  • Management and Organizational Practices
  • Telomeres, Telomerase, and Senescence
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Scoliosis diagnosis and treatment
  • Biomarkers in Disease Mechanisms
  • Connective tissue disorders research
  • Lipoproteins and Cardiovascular Health
  • Cardiac tumors and thrombi
  • Aortic Disease and Treatment Approaches
  • Eosinophilic Disorders and Syndromes
  • Liver Diseases and Immunity
  • Monoclonal and Polyclonal Antibodies Research

Akademii Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach
2024

Poznan University of Medical Sciences
2017-2023

Mater Misericordiae University Hospital
2021-2022

University of Szeged
2014-2019

Medical University of Silesia
2005-2019

Medical University of Warsaw
2018

Medical University of Białystok
2016

Central Clinical Hospital
2013-2015

Nofer Institute of Occupational Medicine
2014

Background: Several perioperative inflammatory markers are postulated to be significant factors for long-term survival after off-pump coronary artery bypass surgery (OPCAB). Hematological parameters, whether single or combined as indices, provide higher predictive values. Methods: The study group comprised 538 consecutive patients (125 (23%) females and 413 (77%) males) with a mean age of 65 ± 9 years, who underwent OPCAB follow-up time 4.7 1.7 years. This single-center retrospective...

10.3390/cells11071124 article EN cc-by Cells 2022-03-26

Cardiovascular diseases, apart from commonly known risk factors, are related to inflammation. There several simple novel markers proposed present the relation between inflammatory reactions activation and atherosclerotic changes. They easily available whole blood count include neutrophil lymphocyte ratio (NLR), monocyte (MLR), platelets (PLR). The RDW results were excluded analysis.The study based on retrospective single-centre analysis of 682 consecutive patients (131 (19%) females 551...

10.3390/biology11010034 article EN cc-by Biology 2021-12-27

Abstract The objective of this study was to assess the thoracic kyphosis (ThKA) and lumbar lordosis (LLA) in healthy young adults investigate potential relationships between spinal curvatures, self-reported physical activity (PA), somatic parameters. included 380 female students 211 male aged 20.7 ± 1.5 years. ThKA LLA were measured using a Plurimeter-V gravity inclinometer. level PA estimated International Physical Activity Questionnaire. lower women compared men, while higher than men (p...

10.1038/s41598-024-62929-9 article EN cc-by Scientific Reports 2024-05-28

Diabetes mellitus (DM) represents a complex carbohydrate metabolism disorder characterized by inflammatory over-reactivity. The study aimed to investigate the potential influence of postoperative activation on mortality risk after off-pump coronary artery bypass grafting in diabetic patients. There were 510 patients treated with due stable disease, including 175 type-2 DM (T2DM.) mean follow-up time was 3.7 +/− 1.5 years 9% all-cause rate group. In multivariable analysis, preoperative...

10.3390/diagnostics12030634 article EN cc-by Diagnostics 2022-03-04

Coronary artery bypass revascularization is still the optimal treatment for complex coronary disease with good long-term results. The relation between inflammatory activation in post-operative period and prognosis was already postulated. possible predictive role of preoperative indexes after off-pump grafting technique on long term survival aim study. Study population included 171 patients a median age 64 years (59-64) operated using January December 2014. Patients enrolled current study...

10.1371/journal.pone.0276138 article EN cc-by PLoS ONE 2022-12-15

Carotid artery stenosis is often considered a stable clinical condition, and the underlying atherosclerosis thought to have an inflammatory background.The aim of study was assess value different parameters obtained from whole blood counts for prediction advanced carotid atherosclerosis, including vessel occlusion, irrespective symptom occurrence.The group comprised 290 patients (84 (29%) females 206 (71%) males) with mean age 68 ±8 years, who were admitted Vascular Surgery Department due...

10.17219/acem/159756 article EN cc-by Advances in Clinical and Experimental Medicine 2023-03-15

BACKGROUND Cardiovascular disease (CVD) is an important aggravating factor for orthotopic liver transplantation (OLT) outcomes. CVD still seems to be one of the most common cause death in long-term post-transplant period. Nevertheless, there are some limited data regarding optimal strategy risk assessment during OLT candidate evaluation. MATERIAL AND METHODS Routine pre-transplant cardiac workup 360 patients with end stage (ESLD) included electrocardiogram, echocardiography, and exercise...

10.12659/aot.908771 article EN Annals of Transplantation 2018-08-21

The electrical properties of cells and tissues in relation to energy exposure have been investigated, presenting their resistance capacitance characteristics. dielectric response radiofrequency fields exhibits polarization heterogeneity under pathological conditions. aim the study was analyze differences changes measurements range from 1 kHz MHz, combined with an assessment correlation between results impedance spectroscopy (EIS) inflammatory activation.In prospective study, EIS performed on...

10.3390/ijerph20032745 article EN International Journal of Environmental Research and Public Health 2023-02-03

Biological therapies used in psoriasis treatment pose a risk of reactivation hepatitis B virus (HBV) infection. This occurs not only patients with HB surface antigen (HBsAg) (+) but also past or occult HBV infection (with negative HBsAg, positive core antibodies (HBcAb), and deoxyribonucleic acid [DNA]). Ustekinumab (UST) is biologic agent acts by blocking the IL-12/23 pathway. Thus, hindering this response may lead to reactivation. UST therapy associated mild HBV-r risk; however, there...

10.1111/dth.15274 article EN Dermatologic Therapy 2021-12-18

Background and objective: Coronary artery disease is one of the leading causes deaths nowadays trends in diagnosis revascularization are still plateau despite well-known factors. Simple whole blood count parameters may be used to measure inflammatory reactions that involved processes atherosclerosis progression. The aim our study was analyse association between simply available hematologic indices long-term mortality following off-pump coronary bypass grafting (OPCAB). Material Methods:...

10.3390/medicina57121324 article EN cc-by Medicina 2021-12-03

Combination therapy with pegylated interferon, ribavirin and a first-generation NS3/4A protease inhibitor, telaprevir or boceprevir, is the new strategy for treatment of genotype 1 chronic hepatitis C virus infection. This combination improves therapeutic efficacy but it also increases risk adverse events.The aim study was to analyze frequency severity dermatological events during inhibitor-based evaluate factors their development.This retrospective 109 patients treated boceprevir (n=33)...

10.3315/jdcr.2014.1183 article EN Journal of Dermatological Case Reports 2014-12-31

Cardiac surgeons have to face the problem of impaired left ventricle function in patients undergoing routine valve or coronary procedures. The intra-aortic balloon pump is not always effective preventing cardiac failure. idea using a microaxial rotating as short-term perioperative support seems be convenient solution. case patient with dilated cardiomyopathy combined mitral and surgery elective use Impella LD presented. Various options applying device are discussed, especially bridge...

10.5114/kitp.2015.50570 article PL cc-by-nc-sa Polish Journal of Cardio-Thoracic Surgery 2015-01-01

(1) Background: The combination of candidate selection, immunosuppressive therapy adjustment, and scrutinous monitoring is a cornerstone for optimizing long-term survival after heart transplant. Neutrophil-to-lymphocyte ratio (NLR) simple marker inflammatory reactions activation may play clinical role as predictive in oncological cardiovascular diseases. aim the study was to find hematologic indices available from whole blood count help monitoring. (2) Methods: Thirty patients (23 men 7...

10.3390/diagnostics12010037 article EN cc-by Diagnostics 2021-12-24

A man in his 40s was referred to our centre with rapidly progressive interstitial lung disease for transplant evaluation. Three months prior presentation he had developed periorbital oedema and discolouration, papules over the dorsal aspect of metacarpophalangeal (MCP) joints mucocutaneous ulcerations dorsum palmar aspects MCPs. He also been experiencing shortness breath. Based on characteristic appearance cutaneous lesions, lack muscle weakness clinical examination, rapid progression...

10.1136/bcr-2021-246192 article EN BMJ Case Reports 2022-03-01

Telomerase is a reverse transcriptase that adds repetitive telomere sequences to the end of chromosomes, which thought be essential for cellular immortality and oncogenesis. The enzyme consists three subunits: human telomerase (hTERT), RNA (hTR), protein 1 (TP1). hTERT subunit determines activity as an detected in most tumors regenerative cells. But many studies have revealed hTR TP1 are expressed constitutively. This resuts suggest subunits may potentially good markers endogenous control....

10.1136/ijgc-00009577-200503000-00026 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2005-02-01

W Polsce współczynnik zapadalności na gruźlicę jest wyższy niż średnia dla krajów Unii Europejskiej, Norwegii czy Islandii

10.13075/mp.5893.2014.043 article PL cc-by-nc Medycyna Pracy 2014-05-01

Wprowadzenie. Otyłość i nadwaga wśród młodzieży to problem, który od lat wykazuje tendencje wzrostowe mimo wielu kampanii programów prowadzonych przez różne instytucje. Czynnikami mającymi realny wpływ na duże wartości BMI są głównie nieprawidłowe żywienie oraz niedostateczna ilość/brak ruchu.Cel pracy. Analiza aktywności fizycznej sposobu żywienia z III Liceum Ogólnokształcącego w Białymstoku Zespołu Szkół Zawodowych nr 5 Białymstoku.Materiał metody. Badaniem objęto 304 uczniów dwóch szkół,...

10.17219/pzp/64698 article PL Nursing and Public Health 2016-12-14

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Smoczyński R, Sarnowski W, Kłapyta A, et al. CARDIAC SURGERYEarly experience with implantation of the new biological Trifecta valve. Kardiochirurgia i Torakochirurgia Polska/Polish Journal Thoracic and Cardiovascular Surgery. 2013;10(2):105-109. doi:10.5114/kitp.2013.36126. APA Smoczyński, R., Sarnowski, W., Kłapyta, A., Szafron, B., Kosior, D., & Sypuła, S. (2013). Surgery, 10(2), 105-109....

10.5114/kitp.2013.36126 article EN cc-by-nc-sa Polish Journal of Cardio-Thoracic Surgery 2013-01-01

AMA Tyczyński P, Ferrante G, Witkowska A, et al. Images in cardiologyDifferent patterns of stent endothelialization and restenosis at follow-up. Optical coherence tomography observations. Advances Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2011;7(3):248-251. doi:10.5114/pwki.2011.24743. APA Tyczyński, P., Ferrante, G., Witkowska, A., Lindsay, Foin, N., & Ghilencea, L. (2011). Interwencyjnej, 7(3), 248-251. https://doi.org/10.5114/pwki.2011.24743 Chicago Paweł, Giuseppe...

10.5114/pwki.2011.24743 article EN cc-by-nc-sa Advances in Interventional Cardiology 2011-01-01

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Witkowska A, Urbanowicz T, Olasińska-Wiśniewska Katarzyński S, Perek B, Jemielity M. A large asymptomatic postinfarction left ventricular pseudoaneurysm – an incidental finding during a recurrent coronary event. Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery. 2023;20(1):47-49. doi:10.5114/kitp.2023.126099. APA Witkowska, A., Urbanowicz, T., Olasińska-Wiśniewska,...

10.5114/kitp.2023.126099 article EN cc-by-nc-sa Polish Journal of Cardio-Thoracic Surgery 2023-01-01

<b>Introduction:</b> sarcoidosis and IPF are diffuse parenchymal lung diseases with a complex immune background. Bronchoalveolar lavage fluid (BALf) is used to investigate inflammation response at the local level. <b>Aim:</b> evaluation mRNA expression of selected mediators (CCL26, ECP, IL10, IL12p40, IL13, IL17, IL2, IL25, IL33, IL6, IL8, MCP1, MMP9, PCNA, TGF, TSLP, mast cell tryptase) in BALf cells from patients its correlation clinical data. <b>Methods:</b> total RNA isolated suspensions...

10.1183/1393003.congress-2017.pa3820 article EN 2017-09-01
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