A5102007069- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Gout, Hyperuricemia, Uric Acid
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Advanced Neuroimaging Techniques and Applications
- Inflammasome and immune disorders
- Vasculitis and related conditions
- Schizophrenia research and treatment
- Foot and Ankle Surgery
- Sarcoma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Systemic Sclerosis and Related Diseases
- Drug-Induced Ocular Toxicity
- COVID-19 Clinical Research Studies
- Functional Brain Connectivity Studies
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Polyomavirus and related diseases
- Lower Extremity Biomechanics and Pathologies
- Multiple Sclerosis Research Studies
- Eosinophilic Disorders and Syndromes
- Liver Disease Diagnosis and Treatment
- Neurological and metabolic disorders
Mater Misericordiae University Hospital
2006-2024
University College Dublin
1993-2024
Brown Foundation
2023
Nationwide Children's Hospital
2023
King's College Hospital
2018-2020
King's College Hospital NHS Foundation Trust
2017-2020
Yale University
2019
Cork University Hospital
2010-2013
Center for Rheumatology
2013
St. Vincent's University Hospital
2010
Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) EULAR have developed the first‐ever CPPD disease. Methods Supported by ACR EULAR, a multinational group investigators followed established methodology to develop these criteria. generated lists candidate items refined their definitions, collected de‐identified patient...
Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) EULAR have developed the first-ever CPPD disease.Supported by ACR EULAR, a multinational group investigators followed established methodology to develop these criteria. generated lists candidate items refined their definitions, collected de-identified patient profiles,...
Hypercoagulability and endothelial dysfunction are hallmarks of coronavirus disease 2019 (COVID-19) appear to predict severity. A high incidence thrombosis despite thromboprophylaxis is reported in patients with moderate severe COVID-19. Recent randomized clinical trials suggest that therapeutic-intensity heparin confers a survival benefit moderate-severity COVID-19 compared standard-intensity heparin, potentially by harnessing heparin-mediated endothelial-stabilizing anti-inflammatory...
Six patients with bilateral paramedian thalamic infarction were seen in a general hospital over 4 year period. This distinct stroke syndrome was recognized by the features of disturbed vigilance, often episodic, vertical gaze disorder. Other signs included an amnesic syndrome, convergence difficulty, third nerve palsies, eyelid retraction, dysarthria, ataxia and involuntary limb movements. Diagnosis confirmed CT brain scan or magnetic resonance imaging. A variety risk factors for present....
The frequent association of affective disorder and multiple sclerosis raises important aetiological clinical considerations. Reported here are seven patients who presented with symptoms had a preceding history bipolar disorder. hypothesis that illness may be the initial manifestation is discussed reference to relevant epidemiological research on topic.
Objectives Anti-citrullinated protein antibodies (ACPA) have been shown to cause platelet activation in vitro, through the low-affinity immunoglobulin G (IgG) receptor (FcγRIIa) on platelets. Platelet via engagement of FcγRIIa results proteolytic cleavage and shedding specific glycoprotein VI (GPVI) which can be detected plasma as soluble GPVI (sGPVI). We hypothesized that levels sGPVI would increased among patients with seropositive RA a consequence antibody-induced shedding. Methods...
This study assesses the role of orthopantomography, computerized tomography and intra-operative assessment in predicting presence extent mandibular invasion by mouth tumours. Forty patients with squamous carcinoma oral cavity oropharynx were studied. All had pre-operative orthopantomography as well these factors compared actual histological to assess each test. found that negative radiology is useful for excluding cortical might be expected no real value periosteal invasion, a positive...