A5008322861- Olfactory and Sensory Function Studies
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Neonatal Respiratory Health Research
- Innovation and Socioeconomic Development
- Pregnancy and preeclampsia studies
- COVID-19 Clinical Research Studies
- Essential Oils and Antimicrobial Activity
- Knowledge Management and Sharing
- Venous Thromboembolism Diagnosis and Management
- Neurological Disease Mechanisms and Treatments
- Neurobiology and Insect Physiology Research
- COVID-19 and healthcare impacts
- Allergic Rhinitis and Sensitization
- Optics and Image Analysis
- Nasal Surgery and Airway Studies
- Inflammatory Biomarkers in Disease Prognosis
- Web and Library Services
- Memory and Neural Mechanisms
- Platelet Disorders and Treatments
- Sensory Analysis and Statistical Methods
- Innovations in Medical Education
- Geophysics and Sensor Technology
- Medical Coding and Health Information
- Library Collection Development and Digital Resources
Chelsea and Westminster Hospital NHS Foundation Trust
2025
University of California, San Diego
2006-2023
San Diego State University
2010-2023
Rotunda Hospital
2020-2023
National Maternity Hospital
2018-2023
Royal College of Surgeons in Ireland
2019-2022
University College Dublin
2020-2022
The University of Western Australia
2014-2017
The University of Melbourne
2005-2014
University of California San Diego Medical Center
1992-2009
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and evidence COVID-19-induced endothelial dysfunction have been reported, precise aetiology increased thrombotic risk associated with COVID-19 infection remains be fully elucidated. Therefore, we assessed clinical platelet parameters circulating activity in patients severe nonsevere COVID-19. An...
Journal Article Unawareness of Smell Loss in Normal Aging and Alzheimer's Disease: Discrepancy between Self-Reported Diagnosed Sensitivity Get access Steven Nordin, Nordin 1University California Medical CenterSan DiegoDepartment Psychology, San Diego State University Search for other works by this author on: Oxford Academic PubMed Google Scholar Andreas U. Monsch, Monsch 2Department Psychiatry, School Medicine, CaliforniaSan Claire Murphy Address correspondence reprint requests to Dr....
Abstract The impact of lexical functioning and detection sensitivity on the deficit odor identification in Alzheimer's disease (AD) was studied persons diagnosed with probable questionable AD. Tests consisted lexical-based identification, picture picture-based odor-detection threshold. Results suggest (1) that is poorer than AD, (2) continues to be poor even when demands are eliminated, (3) does contribute odor-identification deficit, but not account for it completely, (4) tests have a...
To determine whether odor identification ability is associated with the 5-year incidence of cognitive impairment in a large population older adults normal cognition at baseline and olfactory contributes to prediction decline.Population-based longitudinal study.Beaver Dam, Wisconsin.One thousand nine hundred twenty participants Epidemiology Hearing Loss Study (mean age 66.9).Olfaction was measured using San Diego Odor Identification Test (SDOIT). Incident defined as Mini-Mental State...
In four experiments, young (18-26 years, M = 21) and elderly (over 65 72) people were compared for recognition memory of (a) graphic stimuli (faces presidents vice presidents, engineering symbols, free forms) (b) everyday odors. On stimuli, the consistently matched young, but on odors performance was worse. Their poorer olfactory observed after only 26 s, became truly marked 1 hr or more. Somewhere between 2 weeks, their odor fell to chance, remained well above chance. Although did forget...
<h3>Background:</h3> Smell impairment affects 1% to 2% of Americans and leads frequent physician visits. Olfactory testing is available in chemosensory centers, but not as part a routine cranial nerve examination. The alcohol sniff test (AST), which uses the standard 70% isopropyl pad, was developed quick, reliable measure olfactory function. <h3>Methods:</h3> Sixty-four patients 36 healthy control subjects (N=100) were tested with AST butanol threshold test. <h3>Results:</h3> reliably,...
Participants were 20 persons half of whom 18 to 26 years age (M = 21) and over 65 75). All ambulatory, noninstitutionalized, reported good excellent health. The stimulus was menthol delivered in air the nostrils. Threshold measured using up-down staircase method. Intensity pleasantness by magnitude estimation. average threshold for elderly participants significantly higher than young participants. median slope intensity function steeper a factor two younger adults. functions persons....
Argues that co‐operative education allows students to acquire essential practical skills through exposure the real world. Uses a qualitative approach reveal factors perceive as influencing their experiences. Study methodology allowed experience empowerment participation in study.
Abstract Neuropathology in Huntington's disease (HD) known to project areas that process olfactory information raises the questions of which function, if any, is most affected HD, and how explain such dysfunction terms sensitivity cognition. These were studied by comparing HD patients controls (matched for age, gender, education) on absolute detection, intensity discrimination, quality short-term recognition memory, lexical- picture-based identification odor. Taste or vision used as...
Purpose The purpose of this article is to review the extant literature on CPE amongst nurses and concentrate discovering factors that motivate inhibit participation in for Ireland. Design/methodology/approach A was carried out continuing professional development Ireland, UK, USA Australia. From this, research hypotheses were developed. primary concentrated a cohort practicing registered participating course at third‐level institution questionnaire used contained both open closed‐ended...
Hypercoagulability and endothelial dysfunction are hallmarks of coronavirus disease 2019 (COVID-19) appear to predict severity. A high incidence thrombosis despite thromboprophylaxis is reported in patients with moderate severe COVID-19. Recent randomized clinical trials suggest that therapeutic-intensity heparin confers a survival benefit moderate-severity COVID-19 compared standard-intensity heparin, potentially by harnessing heparin-mediated endothelial-stabilizing anti-inflammatory...
Objective To assess the relationship between plasma ferritin concentrations and (1) antenatal factors (2) requirement for red cell transfusion. Study design This single-site prospective study recruited infants in first week of life who were born <32 weeks’ corrected gestational age did not receive a transfusion prior to sampling. Ferritin assessed on discard taken as part routine neonatal investigations (median day life=3, IQR 2–5 days). Reasons delivery, placental histology demographics...
Areas of the brain affected in early stages Alzheimer's disease are also areas heavily involved processing olfactory information. Olfactory event-related potentials (OERPs) and auditory ERPs were recorded from Fz, Cz, Pz electrode sites 12 (AD) patients age gender matched normal controls (NC) a single-stimulus paradigm with 45 s inter-trial interval, using amyl acetate as stimulus, separate session 500 Hz tone stimulus. Odor identification (ID) was used to assess ability identify odors. The...
The prevalence of parosmia and phantosmia among 363 chemosensory nasal/sinus patients was studied, as the accuracy with which our clinical questionnaire could assess these dysfunctions. We then investigated whether or phantosmia, matched for odor intensity, perform poorer on identification than do no dysosmia. More 40% study group evidenced either (18.7%) and/or (25.6%), a finding that suggests more attention should be paid by medical practitioner in addressing qualitative olfactory...
The recent coronavirus pandemic (COVID-19) has affected the delivery of routine cancer care and supportive services. Macmillan Move More Northern Ireland (MMNI) programme provides access to physical activity behavioural change support before, during after treatment. This evaluation details impact on MMNI participants identifies methods adapt service delivery.A multiple-choice short answer online survey was sent 730 participants, investigate initial, national COVID-19 lockdown. Specifically,...
use of an odor learning test and the California Verbal Learning Test in young elderly adults enabled comparison age-related effects on recall recognition memory. Assessment identification further study which function (recall, identification, recognition) is most affected by aging, functions' interrelationships, predictors recall. Results suggested that both were significantly aging odor-recall decline cannot simply be referred to poor identification. Very similar effect sizes found for 3...
Background The aim of this study was to measure olfactory impairment in patients with various etiologies using symptom ratings and psychophysical measures function. Methods We performed a cross-sectional, population-based at the Nasal Dysfunction Clinic University California, San Diego (UCSD), Medical Center. One thousand consecutive presented UCSD for evaluation chemosensory dysfunction. Olfactory assessed by odor threshold identification scores were self-report. Results degree driven...
Neural bases of human olfactory memory are poorly understood. Very few studies have examined neural substrates associated with correct odor recognition, and none has tackled networks incorrect recognition. We investigated the basis task performance during a yes-no recognition paradigm in young elderly subjects using event-related functional magnetic resonance imaging. explored four response categories: (Hit) (False Alarm) as well (CR) (Miss) rejection, we characterized corresponding brain...