A5030412436- Neonatal Respiratory Health Research
- Congenital Heart Disease Studies
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- Respiratory Support and Mechanisms
- Child and Adolescent Health
- Cardiovascular Function and Risk Factors
- Pregnancy and preeclampsia studies
- Neonatal and fetal brain pathology
- Cardiovascular Conditions and Treatments
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Mechanical Circulatory Support Devices
- Innovations in Medical Education
- Blood Coagulation and Thrombosis Mechanisms
- Pharmaceutical studies and practices
- Streptococcal Infections and Treatments
- COVID-19 Impact on Reproduction
- Neonatal Health and Biochemistry
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Preterm Birth and Chorioamnionitis
- Adolescent and Pediatric Healthcare
- Cardiovascular Issues in Pregnancy
Royal College of Surgeons in Ireland
2016-2025
Rotunda Hospital
2016-2025
Children's Health Ireland at Crumlin
2022
Temple Street Children's University Hospital
2014-2020
National Maternity Hospital
2005-2010
University College Dublin
2007
NIHR Bristol Cardiovascular Biomedical Research Unit
2006
University of Bristol
2006
Royal Women's Hospital
2002-2005
St. Vincent's Hospital
1994
Objective To assess the relationship between plasma ferritin concentrations and (1) antenatal factors (2) requirement for red cell transfusion. Study design This single-site prospective study recruited infants in first week of life who were born <32 weeks’ corrected gestational age did not receive a transfusion prior to sampling. Ferritin assessed on discard taken as part routine neonatal investigations (median day life=3, IQR 2–5 days). Reasons delivery, placental histology demographics...
Coarctation of the aorta (CoA) is associated with hypertension and abnormalities blood pressure control, which persist after late repair. Assumptions that neonatal repair would prevent development have not been supported by recent data. We hypothesized early pathological adjustment autonomic cardiovascular function may already be established in neonate coarctation.We studied 8 otherwise well neonates simple CoA compared measures spontaneous baroreflex sensitivity, heart rate variability,...
<b><i>Background:</i></b> Few published data exist to guide interpretation of coagulation times in extremely premature infants. <b><i>Objective:</i></b> To determine reference ranges on day 1 life <b><i>Methods:</i></b> A retrospective review tests was performed 144 infants <27 weeks' gestation between 2004 and 2010 a tertiary neonatal unit. Samples were drawn through non-heparinized umbilical or peripheral venous...
Background and Aims There is a paucity of data on left ventricle (LV) rotational physiology in neonates. We aimed to assess mechanics infants with hypoxic ischemic encephalopathy (HIE) premature (<32 weeks) at 36 weeks postmenstrual age (PMA) (preterm group) compare them healthy term controls (term controls). also compared the parameters preterm without chronic lung disease (CLD). Methods Echocardiography was performed within 48 hours birth or PMA. LV basal apical rotation, twist (and...
Noise levels above 45 dB in a neonatal intensive care unit (NICU) and 60 during transport are recognised hazards, but protective equipment is not standard. We measured noise both settings, with without protection.
Studies have demonstrated increased morbidity and mortality with platelet transfusions in the neonatal period. Platelets are as important for host immunity inflammation hemostasis. Increased may explain dose-associated increase mortality, bleeding, lung disease.This study aims to assess if there any changes inflammatory cytokines post-platelet transfusion babies NICU.This prospective observational recruited due receive a non-emergency transfusion. Dried whole blood samples were collected...
Abstract Background: Guidelines recommend neonatal resuscitation without controlling tidal volume or positive end‐expiratory pressure (PEEP). However, these may improve gas exchange, lung and outcome. Aim: To investigate of very premature lambs with a Laerdal bag PEEP versus guarantee ventilation PEEP. Methods: Anaesthetized ( n =20) delivered at 125 d gestation were randomized to three groups receiving 15 min resuscitation: (1) no PEEP; (2) 5 ml/kg 8 cm H 2 O (3) 10 They then all ventilated...
This pilot study assessed the diagnostic accuracy and potential impact of a rapid PCR-based screening test for detection group B Streptococcus (GBS) at onset labour purpose optimising intrapartum antibiotic prophylaxis (IAP). Vaginal rectal swabs from convenience sample 158 women were analysed by conventional broth-enriched culture PCR test. Overall, GBS carriage was 18.98% 19.62% PCR. had sensitivity 93.1%, specificity 96.67% area under curve (AUC) 0.95. Only 19.3% GBS-positive received...
Serum albumin is a predictor of outcome in adults but its role paediatric patients unclear. Earliest was not associated with mortality or morbidity very low birth weight (VLBW) infants. However, the lowest serum had statistically significant inverse correlation and potentially plays prognostic VLBW neonates.