A5085282813- Neonatal Health and Biochemistry
- Neonatal Respiratory Health Research
- Blood transfusion and management
- Neonatal and fetal brain pathology
- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Intravenous Infusion Technology and Safety
- Thermal Regulation in Medicine
- Neonatal and Maternal Infections
- Electric Vehicles and Infrastructure
- Vehicle emissions and performance
- Blood disorders and treatments
- Pediatric health and respiratory diseases
- Infectious Encephalopathies and Encephalitis
- Parvovirus B19 Infection Studies
- Respiratory Support and Mechanisms
- Central Venous Catheters and Hemodialysis
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Palliative Care and End-of-Life Issues
- Hemoglobinopathies and Related Disorders
- Trauma and Emergency Care Studies
- Air Quality and Health Impacts
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
National Maternity Hospital
2019-2025
University College Dublin
2023-2025
Coombe Women & Infants University Hospital
2019
Assess mortality and neurodevelopmental outcomes at 2 years of corrected age in children who participated the PlaNeT-2/MATISSE (Platelets for Neonatal Transfusion - 2/Management Thrombocytopenia Special Subgroup) study, which reported that a higher platelet transfusion threshold was associated with significantly increased or major bleeding compared to lower one.Randomised clinical trial, enrolling from June 2011 August 2017. Follow-up complete by January 2020. Caregivers were not blinded;...
Importance Red blood cell (RBC) transfusions are frequently administered to preterm infants born before 32 weeks of gestation in the neonatal intensive care unit (NICU). Two randomized clinical trials (Effects Transfusion Thresholds on Neurocognitive Outcomes Extremely Low-Birth-Weight Infants [ETTNO] and Prematures [TOP]) found that liberal RBC transfusion thresholds nonsuperior restrictive thresholds, but extent which these results have been integrated into practice since publication 2020...
We conducted a retrospective observational study of all transports by our national neonatal transport service to estimate direct carbon emissions produced the in 1 year time period. investigated parts journey for 501 transports-from 27 referring units 15 receiving units. These covered total 110 305.4 km. As vehicles report 293-327 g/km, over period between 32.3 and 36.1 metric tonnes were directly service. Our impact could be mitigated utilisation alternative fuels, including hydrotreated...
Objective Despite lack of evidence supporting efficacy, prophylactic fresh frozen plasma and Octaplas transfusions may be administered to very preterm infants reduce bleeding risk. International variation in transfusion practices neonatal intensive care units (NICUs) is poorly understood, therefore, we aimed describe practice Europe. Design Prospective observational study. Setting 64 NICUs 22 European countries, with a 6-week study period per centre between September 2022 August 2023....
Studies have demonstrated increased morbidity and mortality with platelet transfusions in the neonatal period. Platelets are as important for host immunity inflammation hemostasis. Increased may explain dose-associated increase mortality, bleeding, lung disease.This study aims to assess if there any changes inflammatory cytokines post-platelet transfusion babies NICU.This prospective observational recruited due receive a non-emergency transfusion. Dried whole blood samples were collected...
In adult patients with acute respiratory failure, nasal high-flow (NHF) therapy at the time of intubation can decrease duration hypoxia. The objective this pilot study was to calculate peripheral oxygen saturation below 75% during single and multiple attempts in order inform development a larger definitive trial.This double-blinded randomised controlled trial conducted single, tertiary neonatal centre from October 2020 2021.Infants undergoing oral intensive care were included. Infants upper...
The clinical significance of serologic reactivity unidentified specificity (SRUS) in pregnancy is not clear based on available literature. aim this study to determine if SRUS associated with hemolytic disease the fetus and newborn (HDFN).Retrospective data were collected from eight institutions over an 11-year period (2010-2020), when (5/8 sites). outcome pregnancies SRUS-no, mild, moderate, or severe HDFN-was determined.SRUS was demonstrated 589 pregnancies. After excluding those incomplete...
Blood component transfusion is a common intervention in the neonatal intensive care unit (NICU). Parents consent on their babies' behalf. This study aimed to explore parents' understandings and experiences of consenting subsequent blood transfusion.A "low inference" qualitative descriptive semi-structured interview approach was utilised. Grounded theory employed. described memories transfusions, responses process assessed written information they were given.A purposive sample 17 parents...
Objective To assess the safety and feasibility of platelet transfusion through small-bore long lines used in neonatal intensive care unit (NICU), including double-lumen umbilical venous catheters (UVCs) 24 G 28 peripherally inserted central (PICCs). Design Prospective vitro controlled study. Setting Blood service laboratory. Methods In transfusions were set up as per NICU practice. Transfusion line pressure was monitored. Post-transfusion swirling, presence aggregates, pH analysis automated...
<h3>Background and aims</h3> Parenteral nutrition is a vital part of our management neonates in the NICU. The National Paediatric Neonatal Nutrition Guidelines were introduced November 2016. national guidelines recommend checking serum triglyceride levels on day 3–4 5–7 PN administration, as well weekly thereafter if stable. We noted that this was not occurring unit so aimed to audit compliance with lipid monitoring receiving parenteral order target quality improvement initiative....
<h3>Aim</h3> The 7th edition of the Neonatal Resuscitation Programme (NRP) from American Academy Paediatrics (AAP) is used as safe standard neonatal resuscitation in Republic Ireland. NRP details minimum equipment requirements. Anecdotal reports our tertiary maternity hospital suggested a lack adherence to this list, and that delivery room environment may be an unsafe place for neonates. Delayed could have significant clinical medicolegal consequences. Audit demonstrated poor compliance with...