A5010448125- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Atrial Fibrillation Management and Outcomes
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Cardiac Arrhythmias and Treatments
- Neonatal Respiratory Health Research
- Neonatal Health and Biochemistry
- Neonatal and fetal brain pathology
- Mast cells and histamine
- Immunodeficiency and Autoimmune Disorders
- Autoimmune Bullous Skin Diseases
- Ion channel regulation and function
- Platelet Disorders and Treatments
- Erythrocyte Function and Pathophysiology
- Eosinophilic Esophagitis
- Pneumocystis jirovecii pneumonia detection and treatment
- Cardiac pacing and defibrillation studies
- Cannabis and Cannabinoid Research
- Cardiovascular Disease and Adiposity
- Occupational exposure and asthma
- Blood groups and transfusion
- Immunotoxicology and immune responses
- Seaweed-derived Bioactive Compounds
Imperial College London
1999-2024
Homerton University Hospital NHS Foundation Trust
2020-2024
Lung Institute
2024
Guy's and St Thomas' NHS Foundation Trust
2013-2023
Fairfax Neonatal Associates
2023
Melbourne Health
2021
The Royal Melbourne Hospital
2019-2020
Guy's Hospital
2017-2019
Evelina London Children's Healthcare
2018
St Thomas' Hospital
2010-2012
<h3>Introduction</h3> Neonatal infection is an important cause of morbidity and mortality. surveillance networks are necessary for defining the epidemiology infections monitoring changes over time. <h3>Design</h3> Prospective multicentre using a web-based database. <h3>Setting</h3> 12 English neonatal units. <h3>Participants</h3> Newborns admitted in 2006–2008, with positive blood, cerebrospinal fluid or urine culture treated antibiotics at least 5 days. <h3>Outcome measure</h3> Incidence,...
Platelet transfusions are commonly used to prevent bleeding in preterm infants with thrombocytopenia. Data lacking provide guidance regarding thresholds for prophylactic platelet neonates severe thrombocytopenia.In this multicenter trial, we randomly assigned born at less than 34 weeks of gestation whom thrombocytopenia developed receive a transfusion platelet-count 50,000 per cubic millimeter (high-threshold group) or 25,000 (low-threshold group). Bleeding was documented prospectively the...
Assess mortality and neurodevelopmental outcomes at 2 years of corrected age in children who participated the PlaNeT-2/MATISSE (Platelets for Neonatal Transfusion - 2/Management Thrombocytopenia Special Subgroup) study, which reported that a higher platelet transfusion threshold was associated with significantly increased or major bleeding compared to lower one.Randomised clinical trial, enrolling from June 2011 August 2017. Follow-up complete by January 2020. Caregivers were not blinded;...
SUMMARY Objective To describe patterns of clinical bleeding in neonates with severe thrombocytopenia ( ST and platelet count <60 × 10 9 L −1 ), to investigate the factors related bleeding. Study design Seven tertiary‐level neonatal units enrolled n = 169) . Data were collected prospectively on all clinically apparent haemorrhages. Relationships between bleeding, baseline characteristics explored through regression analysis. Results Bleeding was recorded most (138/169; 82%), including 123...
IntroductionBeta-lactams (BL) are the most frequently reported drug allergy, but vast majority of patients found not to be genuinely allergic after evaluation. Few studies have investigated clinical predictors genuine BL and prevalence in hospitalized Chinese is unknown.MethodsPatients admitted a tertiary hospital Hong Kong (HK) were analyzed identify factors associated with presence allergy labels among patients. A combined cohort having completed investigation for suspected allergies...
Autism is well known as a complex developmental disorder with seemingly confusing and uncertain pathogenesis. The definitive mechanisms that promote autism are poorly understood mostly unknown, yet available theories do appear to focus on the disruption of normal cerebral development its subsequent implications functional brain unit. This mini-review aims solely discuss evaluate most prominent current regarding pathogenesis autism. main conclusion although there not clear pathway directed...
The authors have no conflicts of interest to report.
The VenaSeal closure system (Medtronic, Minneapolis, Minn) is a nonthermal, minimally invasive method for the treatment of superficial venous insufficiency using proprietary n-butyl cyanoacrylate. We report case 45-year-old woman who underwent right great saphenous vein with and subsequently had biphasic reaction to cyanoacrylate, confirmed on patch testing that negative results other cyanoacrylates. Despite initial allergic response, which settled antihistamines, follow-up duplex ultrasound...