Prior reports regarding the association between physical activity and subclinical cardiovascular disease have not been consistent. The authors assessed walking pace via questionnaire among 6,482 US adults aged 45–84 years without prior clinical participating in Multi-Ethnic Study of Atherosclerosis from 2000 to 2002. Ankle-brachial index (ABI), coronary artery calcification, internal common carotid intima-media thickness (IMT) were measured. Metabolic equivalent-hours/week calculated. These...

<h3>Objectives</h3> To investigate the association of smoking with various clinical, functional and imaging outcomes in patients early axial spondyloarthritis (SpA). <h3>Methods</h3> 647 inflammatory back pain (IBP) fulfilling at least one internationally accepted SpA criteria available data were included analyses. Clinical, demographic parameters compared between smokers non-smokers a cross-sectional level. Variables significant differences univariate analyses used as dependent variables...

<h3>Objective</h3> To clarify the influence of human leucocyte antigen B27 (HLA-B27) status on phenotype early axial spondyloarthritis (SpA). <h3>Methods</h3> 708 patients with inflammatory back pain (IBP) defined by Calin or Berlin criteria were recruited; 654 fulfilled at least one SpA (modified New York, European Spondyloarthropathy Study Group, Amor Assessment SpondyloArthritis international Society classification for SpA) and included in analyses. Clinical, demographic imaging...

Abstract Introduction To investigate the vaccination rate, reported side effects, and patient concerns for COVID‐19 in patients with rheumatic diseases. Methods A multicentre cross‐sectional study from rheumatology clinics two major hospitals Hong Kong was conducted between June 3, 2021 October 8, 2021. Patient interviews demographics, clinical characteristics, status, factors influencing decisions about were supplemented structured questionnaires. Results Out of 1367 patients, 413 (30.2%)...

Abstract Objective The aim of this study was to develop a deep learning algorithm for detection active inflammatory sacroiliitis in short tau inversion recovery (STIR) sequence MRI. Methods A total 326 participants with axial SpA, and 63 non-specific back pain (NSBP) were recruited. STIR MRI the SI joints performed clinical data collected. Region interests (ROIs) drawn outlining bone marrow oedema, reliable marker inflammation, which formed ground truth masks from ‘fake-colour’ images...

To determine the prevalence of anxiety and depression in axial spondyloarthritis (SpA) patients by a psychiatrist using Chinese-bilingual Structured Clinical Interview for Diagnostic Statistical Manual Mental Disorders, fourth edition patient research version (CB-SCID-I/P), to examine effectiveness Hospital Anxiety Depression Scale (HADS) as screening tool. We recruited 160 Chinese axial-SpA CB-SCID-I/P. Recruited subjects were asked complete HADS. HADS, HADS-depression (HADS-D) subscale...

To develop a deep neural network for the detection of inflammatory spine in short tau inversion recovery (STIR) sequence magnetic resonance imaging (MRI) on patients with axial spondyloarthritis (axSpA).

Spondyloarthritis (SpA) has a significant impact on patients’ quality of life due to functional impairments. Generic health instruments like the EuroQoL 5-dimension (EQ-5D) is important for cost-utility analysis care interventions and calculation quality-adjusted years. However, applicability EQ-5D measure in Chinese patients with SpA currently unknown. Hence, aim study test psychometric properties validate use utility analyses SpA. Prospective consecutive recruitment 220 was conducted....

Background A quantifiable imaging measure to gauge the intensity of individual inflammatory lesions in axial spondyloarthritis (SpA) has not been well established. Previous studies have shown that diffusion-weighted (DW) MRI reflects disease activity SpA. Purpose To determine association between apparent diffusion coefficient (ADC) at discovertebral and individuals with Materials Methods In this prospective study, 243 study participants (mean age ± standard deviation, 43.2 years 13.5) back...

To evaluate left ventricular (LV) function and carotid intima-media thickness (IMT) in patients with axial SpA relationship to underlying disease severity.We recruited 104 50 controls. Detailed transthoracic echocardiography was performed analysed two-dimensional speckle tracking strain analysis for systolic tissue Doppler-derived E/E' diastolic assessment. Carotid IMT measured by ultrasonography subclinical atherosclerosis. Radiological severity of assessed the modified Stoke Ankylosing...

To investigate the association of spinal inflammation on MRI in patients with various clinical, functional and radiological outcomes axial spondyloarthritis (SpA).Three hundred ninety-seven participants SpA back pain were recruited from 10 rheumatology centres. Clinical, biochemical parameters collected underwent spine. features including inflammatory lesions facet joints costovertebral joints, corner lesions, spondylitis assessed. BASFI, Bath Ankylosing Spondylitis Disease Activity Index,...

Pneumocystis jiroveci pneumonia (PJP) is an opportunistic infection affecting immunocompromised individuals. However, evidence regarding the burden and effectiveness of prophylaxis among rheumatic patients remains limited. Delineating epidemiology efficacy urgently needed.

The aims of this study were to determine the effectiveness Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Score-C-Reactive Protein (ASDAS-CRP), Score-Erythrocyte Sedimentation Rate (ASDAS-ESR), and inflammatory markers in screening for axial-joint inflammation as detected by magnetic resonance imaging (MRI) find out factors that could affect scoring indices.One hundred fifty-three Chinese spondyloarthritis patients recruited. Clinical data BASDAI collected, Metrology was...

Background: Drug allergies (DA) are immunologically mediated adverse drug reactions and their manifestations depend on a variety of drug- patient-specific factors. The dysregulated immune system underpinning rheumatological diseases may also lead to an increase in hypersensitivity reactions, including DA. higher prevalence reported DA, especially anti-microbials, restricts the medication repertoire for these already immunocompromised patients. However, few studies have examined impact DA...

Cardiovascular (CVS) diseases are the leading cause of death worldwide and patients with rheumatic have an increased CVS. CVS risk factors events common in spondyloarthritis (SpA). Delineating SpA identifying modifiable would be useful.Patients non-specific back pain (NSBP) were identified rheumatology orthopedics clinics, respectively. Clinical information retrieved. Baseline characteristics incidence rates compared between two groups using age- sex-matched cohort. Propensity score...

Background The Spondyloarthritis Research Consortium of Canada (SPARCC) scoring system is a sacroiliitis grading system. Purpose To develop deep learning‐based pipeline for using the SPARCC Study Type Prospective. Population study included 389 participants (42.2‐year‐old, 44.6% female, 317/35/37 training/validation/testing). A pretrained algorithm was used to differentiate image with/without sacroiliitis. Field Strength/Sequence 3‐T, short tau inversion recovery (STIR) sequence, fast spine...

Early diagnosis of spondyloarthritis (SpA) is essential as anti-tumor necrosis factor therapy can achieve significant symptomatic relief and control disease activity. This study aims to compare the clinical characteristics, activity, functional status a Chinese cohort SpA patients who were re-classified into ankylosing spondylitis (AS) fulfilling modified New York (MNY) criteria, those with undifferentiated (USpA) European Spondyloarthropathy Study Group (ESSG) classification criteria only...

Abstract Objective Using diffusion‐weighted imaging (DWI)‐derived apparent diffusion coefficient (ADC), we aimed to determine the relationship between intensity of spinal inflammation and mobility in patients with axial spondyloarthritis (SpA) early later stages active disease. The Ankylosing Spondylitis Disease Activity Score (ASDAS) was also used for a more comprehensive evaluation. Methods Participants SpA back pain were recruited from 10 rheumatology centers. Clinical, biochemical...

Psychological distress commonly occurs in patients with psoriatic arthritis (PsA). The primary objective of this study was to determine the prevalence depression PsA. secondary explore its associated factors, including socio-demographics, disease activity data and comorbidities.Patients PsA fulfilling Classification Criteria for Psoriatic Arthritis were consecutively recruited from local rheumatology clinics. Depression assessed by a self-administered Chinese-Cantonese version Hospital...

Objective To compare the utility of Diffusion weighted imaging (DWI) with short tau inversion recovery (STIR) sequence in diagnosis early axial spondyloarthritis (SpA). Methods Three hundred and five patients chronic back pain were recruited consecutively from 3 rheumatology centers. Clinical, radiological blood parameters recorded. Patients duration no more than years classified as having disease. STIR DWI sacroiliac joints obtained assessed using Spondyloarthritis Research Consortium...

Objective To investigate the relationship between Ankylosing Spondylitis Disease Activity Score (ASDAS) and intensity of spinal inflammation measured by apparent diffusion coefficient (ADC) in MRI participants with active axial spondyloarthritis (SpA). Methods Participants SpA back pain were recruited. Clinical, demographic, biochemical imaging data collected. ASDAS was calculated based on C reactive protein (CRP) erythrocyte sedimentation rate (ESR). Inflammatory lesions identified short...