Steven Cullen

ORCID: 0000-0002-8281-7174
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Inflammatory Biomarkers in Disease Prognosis
  • Long-Term Effects of COVID-19
  • Platelet Disorders and Treatments
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Venous Thromboembolism Diagnosis and Management
  • Intramuscular injections and effects
  • Adipokines, Inflammation, and Metabolic Diseases
  • Pregnancy and preeclampsia studies

Royal College of Surgeons in Ireland
2019-2022

Tallaght University Hospital
2022

Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory Syndrome 2 (SARS-CoV-2), has affected over 30 million globally to date. Although high rates of venous thromboembolism and evidence COVID-19-induced endothelial dysfunction have been reported, precise aetiology increased thrombotic risk associated with COVID-19 infection remains be fully elucidated. Therefore, we assessed clinical platelet parameters circulating activity in patients severe nonsevere COVID-19. An...

10.1371/journal.pbio.3001109 article EN cc-by PLoS Biology 2021-02-17

Abstract Background Coronavirus disease 2019 (COVID-19), caused by novel coronavirus SARS-CoV-2, has to date affected over 13.3 million globally. Although high rates of venous thromboembolism and evidence COVID-19-induced endothelial dysfunction have been reported, the precise aetiology increased thrombotic risk associated with COVID-19 infection remains be fully elucidated. Objectives Here, we assessed clinical platelet parameters circulating activity in patients severe non-severe COVID-19....

10.1101/2020.07.24.20156240 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-07-26

Vaccine-induced thrombotic thrombocytopenia (VITT) post SARS-CoV-2 vaccination is characterized by and severe thrombosis. Platelet function during patient recovery in the medium-/long-term has not been investigated fully. Here, we undertook a 3-month study, assessing of VITT platelet morphology, granule content dense-granule release at two distinct time points recovery. A 61 year-old female was admitted to hospital 15 days ChAdOx1 nCov-19 vaccination. Hematological parameters peripheral...

10.3389/fcvm.2022.824601 article EN cc-by Frontiers in Cardiovascular Medicine 2022-02-09
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