- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Colorectal Cancer Surgical Treatments
- Global Cancer Incidence and Screening
- Emergency and Acute Care Studies
- Cardiovascular Effects of Exercise
- Hip and Femur Fractures
- COVID-19 epidemiological studies
- Cardiovascular Function and Risk Factors
- Public Health Policies and Education
- Cardiomyopathy and Myosin Studies
- Cardiac Health and Mental Health
- COVID-19 Digital Contact Tracing
- Cardiac electrophysiology and arrhythmias
- Health disparities and outcomes
- Cardiac Arrest and Resuscitation
- HIV, Drug Use, Sexual Risk
- Cancer Risks and Factors
- Nursing Roles and Practices
- Disaster Response and Management
- HIV/AIDS Research and Interventions
- Coronary Interventions and Diagnostics
- Data-Driven Disease Surveillance
- SARS-CoV-2 and COVID-19 Research
University College Dublin
2015-2024
Association of Schools of Public Health in the European Region
2023-2024
Institute of Public Health
2023
Royal Adelaide Hospital
2019
St. Vincent's University Hospital
2019
Mayo Clinic
1987-2015
Mater Misericordiae University Hospital
1995-2010
Marymount University
2010
University of Cincinnati Medical Center
2009
Center for Rheumatology
2009
Using the records linkage system of Mayo Clinic and Rochester Epidemiology Project, which accesses diagnostic data on entire population Olmsted County, Minnesota, we identified 45 new cases idiopathic dilated cardiomyopathy (DCM) 19 hypertrophic (HCM) among county residents for years 1975-1984. Overall age- sex-adjusted incidence rates were 6.0/100,000 2.5/100,000 person-years, respectively. The DCM doubled from 3.9/100,000 in first 5 to 7.9/100,000 person-years last study. corresponding...
Abstract Background Pelvic exenteration for locally recurrent rectal cancer (LRRC) is associated with variable outcomes, the majority of data from single-centre series. This study analysed an international collaboration to determine robust parameters that could inform clinical decision-making. Methods Anonymized on patients who had pelvic LRRC between 2004 and 2014 were accrued 27 specialist centres. The primary endpoint was survival. impact resection margin, bone resection, node status use...
Background:The El Escorial and the revised Airlie House diagnostic criteria for amyotrophic lateral sclerosis (ALS) classify patients into categories reflecting different levels of certainty.We conducted a prospective, population-based study natural course ALS in Republic Ireland during 6-year period to examine utility these criteria.Methods: Using data from Irish Register, we studied clinical features all diagnosed as having throughout their illness.Results: Between 1993 1998, 388 were...
We conducted a prospective, population-based study of ALS in the Republic Ireland for 3-year period 1995 to 1997.To ensure complete case ascertainment, multiple sources information were used, including consultant neurologists, neurophysiologists, primary care physicians, and Irish Motor Neuron Disease Association. The El Escorial diagnostic criteria applied all cases enrolled on register each patient was regularly followed up during his or her illness.Between January 1, 1995, December 31,...
Magnetic resonance (MR) imaging of the breast is currently limited value because lack specificity. Enhanced MR with gadolinium diethylenetriaminepentaacetic acid (DTPA) has been shown to be helpful in further characterization tissue. This prospective study attempted differentiate benign and malignant disease a dynamic enhancement technique. Bolus injection Gd-DTPA short time were used examine 18 patients palpable mass. Construction profiles helped effectively lesion (P less than .001)....
<h3>Background</h3> The Irish ALS Register is a population-based register of the epidemiological characteristics amyotrophic lateral sclerosis (ALS) in republic Ireland. <h3>Objective</h3> To describe clinical and demographic details those patients included who were incorrectly diagnosed as having (patients ultimately rediagnosed an "ALS mimic syndrome"). <h3>Methods</h3> medical records each patient referred to are routinely reviewed and, where possible, examined by our group during their...
▪ Objective: To describe the prognosis of individuals with idiopathic dilated cardiomyopathy in a population-based sample and to compare this patients previous referral center case series cardiomyopathy. Design: Cohort study. Setting: Population-based Olmsted County, Minnesota. Patients: Forty residents Olmstead Minnesotawith initially diagnosed between 1975 1984 who were followed through 1 July 1989 104 from Mayo Clinic 1960 1973. Measurements: Survival for cohort at year 5 years. Results:...
The standard treatment of acute whiplash injuries (soft collar and analgesia) is frequently unsuccessful. Pulsed electromagnetic therapy PEMT (as pulsed 27 MHz) has been shown to have pro-healing anti-inflammatory effects. This study examines the effect on syndrome. One half 40 patients entering received active collars: other facsimile (placebo). All were given instructions wear for eight hours a day at home advised mobilise their necks. At 2 4 weeks actively treated group had significantly...
Considering the chronic and debilitating nature of HIV infection, health-related quality life (HRQoL) is an important patient-reported clinical outcome to better understand effects this infection its treatment on patients' lives. The purpose study was assess HRQoL association with sociodemographic, behavioural, clinical, nutrition-related factors social support in Irish cohort. A cross-sectional, prospective using Medical Outcomes Study Health survey assessed 10 dimensions summarised as...
BackgroundPelvic exenteration for locally advanced rectal cancer (LARC) and recurrent (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes over time.
Abstract To investigate the suggestion that incidence of polycythemia vera has increased in recent decades, we ascertained secular trends Olmsted County, Minnesota, over 55‐year period, 1935–1989. The inpatient and outpatient medical records all potential cases County residents were reviewed diagnostic criteria Polycythemia Vera Study Group applied. We found no indication an increase age‐ sex‐adjusted vera, which averaged 1.9 per 100,000 person‐years (95% C.I., 1.4–2.5) study period....
To compare the performance of two interferon gamma release assays (IGRAs) and conventional screening tests in patients with inflammatory arthritis undergoing for latent tuberculosis infection (LTBI) before treatment anti-tumour necrosis factor alpha (anti-TNFalpha) compounds.Successive were subjected to LTBI screening, including a tuberculin skin test (TST). The T-SPOT.TB was performed on all QuantiFERON-TB Gold large subset. results IGRAs compared tests.A total 150 evaluated. majority...
Sudden arrhythmic death syndrome (SADS) occurs when a person suffers sudden, unexpected death, with no cause found at postmortem examination. We aimed to describe the cardiac screening outcomes in population of relatives SADS victims Prospective and retrospective cohort study consecutive families attending Family Heart Screening clinic Mater Misericordiae Hospital Dublin, Ireland, from January 2007 September 2011. members underwent standard protocol. Adjunct clinical information was sought...
This document outlines the important aspects of caring for patients who have been diagnosed with advanced pelvic cancer. It is primarily aimed at those are establishing a service that adequately caters to this patient group. The relevant literature has summarized and an attempt made simplify approach management these complex cases.
Abstract The evolving landscape of public health necessitates a capable and qualified workforce. Investing in education training is crucial for building maintaining this This article explores the role essential functions (EPHF) shaping education. EPHFs provide framework defining core competencies developing curricula health. WHO-ASPHER Roadmap Core Competency Framework guide professionalization new ASPHER Curriculum further supports educational institutions aligning their programs with these...
Digital technologies promise greater personalisation and precision in public health services, automation of repetitive tasks, more efficient use existing resources through rapid management analysis big data sets. To seize this opportunity, the workforce needs to become sufficiently competent navigate these novel digital understand how apply them across spectrum essential functions. With few exceptions, however, skills are not yet systematically incorporated into curricula.Digital...
We identified a cohort of 300 individuals who had paralytic polio between 1935 and 1955. All lived in Olmsted County, Minnesota. From the 247 survivors, we selected 50 subjects for detailed historical, functional, psychological, clinical, electrophysiologic evaluation. Sixty-four percent these survivors complained new symptoms muscle pain, fatigue, weakness after period prolonged stability. This led to changes lifestyle or activity only 18%. The likelihood expressing complaints was not...