A5055504493- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Medical Imaging Techniques and Applications
- Sinusitis and nasal conditions
- Visual perception and processing mechanisms
- Pediatric health and respiratory diseases
- Ear Surgery and Otitis Media
- Digital Radiography and Breast Imaging
- Infrared Target Detection Methodologies
- Industrial Vision Systems and Defect Detection
- Radiation Dose and Imaging
- Advanced Radiotherapy Techniques
- Nasal Surgery and Airway Studies
- Advanced X-ray and CT Imaging
- CCD and CMOS Imaging Sensors
- Advanced oxidation water treatment
- Dysphagia Assessment and Management
- graph theory and CDMA systems
- Electrochemical Analysis and Applications
- Advanced MRI Techniques and Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Analytical Chemistry and Sensors
- Calibration and Measurement Techniques
- Photoacoustic and Ultrasonic Imaging
- Cardiac, Anesthesia and Surgical Outcomes
University Hospital Southampton NHS Foundation Trust
2015-2025
The University of Texas at Austin
2024
Southampton Children's Hospital
2015-2024
Spectrum Health
2023
Michigan State University
2023
Clinique Hartmann
2020
Royal Hampshire County Hospital
2013-2015
Boston Children's Hospital
2014
Hampshire Hospitals NHS Foundation Trust
2013
Harvard University
2010
We have measured the overall statistical efficiency of human subjects discriminating amplitude visual pattern signals added to noisy backgrounds. By changing noise amplitude, amount intrinsic can be estimated and allowed for. For a target containing few cycles spatial sinusoid about 5 per degree, is as high 0.7 ± 0.07, after correction for noise, reaches 0.83 0.15. Such figure leaves little room residual inefficiencies in neural mechanisms that handle these patterns.
Historically, human signal-detection responses have been assumed to be governed by external determinants (nature of the signal, noise, and task) internal determinants. Variability in is commonly attributed noise (often vaguely defined). We present a variety experimental results that demonstrate observer inconsistency performing noise-limited visual detection discrimination tasks with repeated presentation images. Our can interpreted using model includes an internal-noise component directly...
Research on human-observer performance for noise-limited tasks (such as those found in medical imaging) has recently progressed to investigations which some signal or image parameters are statistically defined. In these cases the ideal-observer procedure is usually nonlinear, and analysis mathematically intractable. Two suboptimal but linear observer models have been proposed mathematical convenience. The Hotelling optimal model give a good fit most human results. nonprewhitening (NPW)...
We have measured the effect of signal-location uncertainty on detectability simple visual signals in uncorrelated image noise. An M-alternative forced-choice identification technique was used with values M ranging from 2 to 1800. find high statistical efficiency (50% for aperiodic signals), and results one value can be predict all others. The are consistent view that humans act as suboptimal maximum a posteriori probability observers.
Proton magnetic resonance has been used to study water in Douglas fir and western red cedar. The free induction decay, when combined with a knowledge of chemical composition the wood, gives an accurate measure absolute moisture content. Spin-lattice relaxation was found be significantly different for two species. In sapwood, three distinct spin—spin times, T2, were measured assigned, help anatomical data, on cell wall, ray latewood tracheid lumens, earlywood lumens. This T2 behavior...
This document outlines the important aspects of caring for patients who have been diagnosed with advanced pelvic cancer. It is primarily aimed at those are establishing a service that adequately caters to this patient group. The relevant literature has summarized and an attempt made simplify approach management these complex cases.
Streptococcus pneumoniaeis one of the key pathogens responsible for otitis media (OM), most common infection in children and largest cause childhood antibiotic prescription. Novel therapeutic strategies that reduce overall consumption due to OM are required because, although widespread pneumococcal conjugate immunization has controlled invasive disease, incidence not decreased. Biofilm formation represents an important phenotype contributing tolerance persistence ofS. pneumoniaein chronic or...
Introduction Primary ciliary dyskinesia (PCD) is a rare, genetic, multiorgan disease with an estimated prevalence of 1 in 10 000. It affects mainly the upper and lower airways due to impaired mucociliary clearance. Almost all patients have sinonasal or otologic (ear–nose–throat, ENT) problems, although ENT clinical phenotype may present great variability. Despite that, data on PCD manifestations are scarce based small single-centre studies. To date, we know little about spectrum severity...
Abstract This study evaluates a new method for chemically destroying organic pollutants in wastewater using spontaneous corrosion of iron metal sheet surfaces the presence hydrogen peroxide. Model (phenol and benzoic acid) were degraded batch experiments to investigate which parameters affected process performance. Iron spontaneously corrode under acidic conditions producing species (mainly ferrous ions) dissolved aqueous solution, react with peroxide via Fenton reaction. In order optimise...
Background Sinonasal symptoms are a common feature of primary ciliary dyskinesia (PCD); however, literature about their severity and frequency, particularly during the life course, is scarce. Using baseline data from Ear, nose throat (ENT) Prospective International Cohort PCD patients, we describe sinonasal disease in PCD. Methods We included participants who had routine examination which they completed questionnaire. compared frequency reported findings among children adults, identified...
Introduction Nearly all patients with primary ciliary dyskinesia (PCD) report ear–nose–throat (ENT) symptoms. However, scarce evidence exists about how ENT symptoms relate to pulmonary disease in PCD. We explored possible associations between upper and lower respiratory among PCD a multicentre study. Methods included from the Prospective International Cohort (EPIC-PCD). studied of several reported chronic rhinosinusitis (defined using patient-reported information examination findings) sputum...
Otologic disease is common among people with primary ciliary dyskinesia (PCD), yet little known about its spectrum and severity.
We have done detailed analysis of 50 excised L1 vertebral bones including single-energy CT, preprocessing dual-energy as well a number physical and chemical analyses to determine the amount fat elemental composition. found good correlation (0.91) between CT measurements mineral element content excellent (0.95) content. The SEEs were 14 10 mg (K2HPO4 equivalent) per cm3 for single dual energy, respectively. also report on variation with respect age, quantitative effect values, relationship...
The final step of the medical imaging process is image display to a human for interpretation. In many cases detectability visual signals limited by statistical fluctuations. Under these circumstances it possible, in principle, calculate best possible signal detection performance. We find that under some conditions humans can closely approach this limiting
Background Recurrent infections of the nose, sinuses and ears are common problems for people with primary ciliary dyskinesia. While pulmonary exacerbations in dyskinesia defined, there is no definition ear-nose-throat exacerbations, a potential outcome research clinical trials. Methods We set up an expert panel 24 specialists, respiratory physicians, other healthcare professionals patients to develop consensus definitions sinonasal otological children adults settings. reviewed literature...
Contrast, relative tube loading, and entrance exposure have been measured for a number of heavy metal filters (Gd, Ho, Yb, W) at several filter thicknesses, voltages (70–100 kV), phantom thicknesses (1.5–2.5 cm aluminum). The rare‐earth consistently gave higher contrast (relative to water) air, CaCl 2 , iodine, oil than the standard mm added aluminum, given voltage. It was found that best choices constant product loading.
We present preliminary results for threshold detection of sharp-edged and "fuzzy" bars discs superimposed on noiseless noisy backgrounds. The luminance profiles the targets were approximately gaussian. background quantum noise is optical density fluctuation in nominally uniformly exposed radiographs. measurements done using method adjustment. Our agreed with previously published work. target are novel demonstrate minima contrast-target size curve. near S to 10 milliradians diameter 2 4...