Isolde Hayn

ORCID: 0009-0000-3766-0705
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Research Areas
  • Cystic Fibrosis Research Advances
  • Sinusitis and nasal conditions
  • Pediatric health and respiratory diseases
  • Otitis Media and Relapsing Polychondritis
  • Tracheal and airway disorders
  • Nasal Surgery and Airway Studies
  • Ear Surgery and Otitis Media
  • Mycobacterium research and diagnosis
  • Head and Neck Surgical Oncology
  • Dysphagia Assessment and Management
  • Immunodeficiency and Autoimmune Disorders

Charité - Universitätsmedizin Berlin
2022-2024

Yin Ting Lam Jean‐François Papon Mihaela Alexandru Andreas Anagiotos Miguel Armengot and 95 more Mieke Boon A. E. Burgess Suzanne Crowley Sinan Ahmed D. Dheyauldeen Nagehan Emiralioğlu Ela Erdem Eralp Christine van Gogh Yasemin Gökdemir Rıza Önder Günaydın Eric G. Haarman Amanda Harris Isolde Hayn Hasnaa Ismail-Koch Bülent Karadağ Céline Kempeneers Sookyung Kim Philipp Latzin Natalie Lorent Uğur Özçelik Charlotte Pioch Anne‐Lise Poirrier Ana Reula Jobst Roehmel Panayiotis K. Yiallouros Myrofora Goutaki Dilber Ademhan Tural Mihaela Alexandru Andreas Anagiotos Miguel Armengot Lionel Benchimol Achim Beule Irma Bon Mieke Boon Marina Bullo A. E. Burgess Doriane Calmès Carmen Casaulta Marco Caversaccio Nathalie Caversaccio Bruno Crestani Suzanne Crowley Sinan Ahmed D. Dheyauldeen Sandra Diepenhorst Nagehan Emiralioğlu Ela Erdem Eralp Pınar Ergenekon Nathalie Feyaerts Gavriel Georgiou Amy Glen Christine van Gogh Yasemin Gökdemir Myrofora Goutaki Rıza Önder Günaydın Eric G. Haarman Amanda Harris Isolde Hayn Simone Helms Sara‐Lynn Hool Isabelle Honoré Hasnaa Ismail Koch Bülent Karadağ Céline Kempeneers Synne Sperstad Kennelly Elisabeth Kieninger Sookyung Kim Panayiotis Kouis Yin Ting Lam Philipp Latzin Marie Legendre Natalie Lorent Jane S. Lucas Bernard Maître Alison McEvoy Rana Mitri-Frangieh David Montani Loretta Müller Noelia Muñoz Heymut Omran Uğur Özçelik Beste Özsezen Samantha Packham Jean‐François Papon Clara Pauly Charlotte Pioch Anne‐Lise Poirrier Johanna Raidt Ana Reula Rico N. P. M. Rinkel Jobst Roehmel Andre Schramm Guillaume Thouvenin Woolf T. Walker Hannah Wilkins Panayiotis K. Yiallouros Ali Cemal Yumuşakhuylu

Background Sinonasal symptoms are a common feature of primary ciliary dyskinesia (PCD); however, literature about their severity and frequency, particularly during the life course, is scarce. Using baseline data from Ear, nose throat (ENT) Prospective International Cohort PCD patients, we describe sinonasal disease in PCD. Methods We included participants who had routine examination which they completed questionnaire. compared frequency reported findings among children adults, identified...

10.1183/23120541.00701-2022 article EN cc-by ERJ Open Research 2023-05-01

Introduction Nearly all patients with primary ciliary dyskinesia (PCD) report ear–nose–throat (ENT) symptoms. However, scarce evidence exists about how ENT symptoms relate to pulmonary disease in PCD. We explored possible associations between upper and lower respiratory among PCD a multicentre study. Methods included from the Prospective International Cohort (EPIC-PCD). studied of several reported chronic rhinosinusitis (defined using patient-reported information examination findings) sputum...

10.1183/23120541.00932-2023 article EN cc-by-nc ERJ Open Research 2024-02-15

Abstract Background Although most patients with primary ciliary dyskinesia (PCD) report sinonasal symptoms, little is known about symptom frequency and severity. We describe manifestations among PCD using data from the Ear, nose, throat (ENT) Prospective International Cohort of patients. Methods included participants routine clinical ENT examinations complete FOLLOW-PCD symptoms questionnaires same visit or within 2 weeks. compared prevalence, reported findings children adults identified...

10.1101/2022.11.23.22282583 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2022-11-28

Introduction Biologic therapies represent new, highly effective treatment options for severe uncontrolled chronic rhinosinusitis with nasal polyposis (CRSwNP). In accordance international and national recommendations the eligibility criteria of biologics in indication CRSwNP, biologic are typically performed patients who have previously undergone sinus surgery still no control disease. case presentation, a patient will be presented primary therapy.

10.1055/s-0044-1785091 article EN Laryngo-Rhino-Otologie 2024-04-19

Einleitung Biologikatherapien stellen neue hocheffektive Therapieoptionen der schweren unkontrollierten Chronischen Rhinosinusitis mit nasaler Polyposis (CRSwNP) dar. Entsprechend internationaler und nationaler Empfehlungen Zulassungskriterien von Biologika in Indikation CRSwNP erfolgen typischerweise bei Patienten, die im Vorfeld eine NNH-Operation erhalten haben sich dennoch keine Kontrolle Erkrankung einstellt. In Fallpräsentation erfolgt Vorstellung eines Patienten einer Nasalen primären...

10.1055/s-0044-1784398 article DE Laryngo-Rhino-Otologie 2024-04-19

ABSTRACT Importance Otologic disease is common among people with primary ciliary dyskinesia, yet little known about its spectrum and severity. Objective We characterized otologic participants dyskinesia using data from the Ear-Nose-Throat Prospective International Cohort of PCD patients (EPIC-PCD). Design Cross-sectional analysis baseline cohort data. Setting Twelve specialized centers in 10 countries. Participants prospectively included children adults diagnoses, routine ENT examinations,...

10.1101/2022.11.16.22282340 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2022-11-18

Abstract Introduction Nearly all patients with primary ciliary dyskinesia (PCD) report ear-nose-throat (ENT) symptoms. However, scarce evidence exists about how ENT symptoms relate to pulmonary disease in PCD. We explored possible associations between upper and lower respiratory among PCD a multicentre study. Methods included from the Prospective International Cohort (EPIC-PCD). studied of several reported chronic rhinosinusitis (CRS)—defined using patient-reported information examination...

10.1101/2023.09.21.23295895 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2023-09-23

Introduction Severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is often associated surgery and recurrence of polyps (NP), sometimes resulting in mucoceles orbital endocranial complications. T2 biologics represent new therapeutic options for CRSwNP. In this real-life study we investigated to what extent CRSwNP patients complicated clinical courses also benefit from therapy biologics.

10.1055/s-0043-1767586 article EN Laryngo-Rhino-Otologie 2023-05-01

Einleitung Die schwere Chronische Rhinosinusitis mit nasaler Polyposis (CRSwNP) ist häufig Operationen und Rezidiven der Nasalen (NP) in Folge dessen z.T. Mukozelen orbitalen endokraniellen Komplikationen assoziiert. T2-Biologika-stellen neue Therapieoptionen bei CRSwNP dar. In Real-Life Studie wurde untersucht, inwieweit auch Patienten komplizierten klinischen Verläufen von Biologikatherapien profitieren.

10.1055/s-0043-1766930 article DE Laryngo-Rhino-Otologie 2023-05-01

<b>Background:</b> Almost all patients with primary ciliary dyskinesia (PCD) have ear-nose-throat (ENT) symptoms, however, little is known about how the upper airways relate to lung disease. We aimed study associations between and lower respiratory symptoms in PCD. <b>Methods:</b> included of ENT Prospective International Cohort (EPIC-PCD) who completed FOLLOW-PCD questionnaire at clinic visit. studied possible reported sputum production shortness breath (SOB), using logistic regression. In...

10.1183/13993003.congress-2023.pa2765 article EN 2023-09-09
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