Isolde Hayn
- Cystic Fibrosis Research Advances
- Sinusitis and nasal conditions
- Pediatric health and respiratory diseases
- Otitis Media and Relapsing Polychondritis
- Tracheal and airway disorders
- Nasal Surgery and Airway Studies
- Ear Surgery and Otitis Media
- Mycobacterium research and diagnosis
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Immunodeficiency and Autoimmune Disorders
Charité - Universitätsmedizin Berlin
2022-2024
Background Sinonasal symptoms are a common feature of primary ciliary dyskinesia (PCD); however, literature about their severity and frequency, particularly during the life course, is scarce. Using baseline data from Ear, nose throat (ENT) Prospective International Cohort PCD patients, we describe sinonasal disease in PCD. Methods We included participants who had routine examination which they completed questionnaire. compared frequency reported findings among children adults, identified...
Introduction Nearly all patients with primary ciliary dyskinesia (PCD) report ear–nose–throat (ENT) symptoms. However, scarce evidence exists about how ENT symptoms relate to pulmonary disease in PCD. We explored possible associations between upper and lower respiratory among PCD a multicentre study. Methods included from the Prospective International Cohort (EPIC-PCD). studied of several reported chronic rhinosinusitis (defined using patient-reported information examination findings) sputum...
Otologic disease is common among people with primary ciliary dyskinesia (PCD), yet little known about its spectrum and severity.
Abstract Background Although most patients with primary ciliary dyskinesia (PCD) report sinonasal symptoms, little is known about symptom frequency and severity. We describe manifestations among PCD using data from the Ear, nose, throat (ENT) Prospective International Cohort of patients. Methods included participants routine clinical ENT examinations complete FOLLOW-PCD symptoms questionnaires same visit or within 2 weeks. compared prevalence, reported findings children adults identified...
Introduction Biologic therapies represent new, highly effective treatment options for severe uncontrolled chronic rhinosinusitis with nasal polyposis (CRSwNP). In accordance international and national recommendations the eligibility criteria of biologics in indication CRSwNP, biologic are typically performed patients who have previously undergone sinus surgery still no control disease. case presentation, a patient will be presented primary therapy.
Einleitung Biologikatherapien stellen neue hocheffektive Therapieoptionen der schweren unkontrollierten Chronischen Rhinosinusitis mit nasaler Polyposis (CRSwNP) dar. Entsprechend internationaler und nationaler Empfehlungen Zulassungskriterien von Biologika in Indikation CRSwNP erfolgen typischerweise bei Patienten, die im Vorfeld eine NNH-Operation erhalten haben sich dennoch keine Kontrolle Erkrankung einstellt. In Fallpräsentation erfolgt Vorstellung eines Patienten einer Nasalen primären...
ABSTRACT Importance Otologic disease is common among people with primary ciliary dyskinesia, yet little known about its spectrum and severity. Objective We characterized otologic participants dyskinesia using data from the Ear-Nose-Throat Prospective International Cohort of PCD patients (EPIC-PCD). Design Cross-sectional analysis baseline cohort data. Setting Twelve specialized centers in 10 countries. Participants prospectively included children adults diagnoses, routine ENT examinations,...
Abstract Introduction Nearly all patients with primary ciliary dyskinesia (PCD) report ear-nose-throat (ENT) symptoms. However, scarce evidence exists about how ENT symptoms relate to pulmonary disease in PCD. We explored possible associations between upper and lower respiratory among PCD a multicentre study. Methods included from the Prospective International Cohort (EPIC-PCD). studied of several reported chronic rhinosinusitis (CRS)—defined using patient-reported information examination...
Introduction Severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is often associated surgery and recurrence of polyps (NP), sometimes resulting in mucoceles orbital endocranial complications. T2 biologics represent new therapeutic options for CRSwNP. In this real-life study we investigated to what extent CRSwNP patients complicated clinical courses also benefit from therapy biologics.
Einleitung Die schwere Chronische Rhinosinusitis mit nasaler Polyposis (CRSwNP) ist häufig Operationen und Rezidiven der Nasalen (NP) in Folge dessen z.T. Mukozelen orbitalen endokraniellen Komplikationen assoziiert. T2-Biologika-stellen neue Therapieoptionen bei CRSwNP dar. In Real-Life Studie wurde untersucht, inwieweit auch Patienten komplizierten klinischen Verläufen von Biologikatherapien profitieren.
<b>Background:</b> Almost all patients with primary ciliary dyskinesia (PCD) have ear-nose-throat (ENT) symptoms, however, little is known about how the upper airways relate to lung disease. We aimed study associations between and lower respiratory symptoms in PCD. <b>Methods:</b> included of ENT Prospective International Cohort (EPIC-PCD) who completed FOLLOW-PCD questionnaire at clinic visit. studied possible reported sputum production shortness breath (SOB), using logistic regression. In...