- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Diverticular Disease and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Pelvic floor disorders treatments
- Inflammatory Bowel Disease
- Enhanced Recovery After Surgery
- Esophageal and GI Pathology
- Colorectal Cancer Treatments and Studies
- Gastrointestinal disorders and treatments
- Esophageal Cancer Research and Treatment
- Appendicitis Diagnosis and Management
- Stoma care and complications
- Hernia repair and management
- Microscopic Colitis
- Anesthesia and Pain Management
- Pelvic and Acetabular Injuries
- Abdominal Surgery and Complications
- Surgical site infection prevention
- Pancreatic and Hepatic Oncology Research
- Infectious Diseases and Tuberculosis
- Minimally Invasive Surgical Techniques
South University
2024
University Hospital Southampton NHS Foundation Trust
2024
Hospital Universitari i Politècnic La Fe
2015-2024
Universitat de València
2014-2024
Hospital Universitario Son Espases
2024
Health Research Institute of the Balearic Islands
2024
Southampton General Hospital
2023
University of Southampton
2023
Agencia Española de Consumo, Seguridad Alimentaría y Nutrición
2010-2022
Catharina Ziekenhuis
2021
In Brief Objective: To determine pre-/intraoperative risk factors for anastomotic leak after colon resection cancer and to create a practical instrument predicting risk. Background: Anastomotic is still the most dreaded complication in colorectal surgery. Many have been identified date, but multicentric prospective studies on are lacking. Methods: Fifty-two hospitals participated this prospective, observational study. Data of 3193 patients, operated with primary anastomosis without stoma,...
Although the early diagnosis of anastomotic leak is a key point in reducing its clinical consequences, daily practice, often late.The aim this study was to determine whether procalcitonin and C-reactive protein are good predictors colorectal surgery.This prospective observational study.This conducted by specialized multidisciplinary team tertiary teaching hospital.A series 205 consecutive patients who underwent elective surgery unit prospectively analyzed. The following data were collected:...
The aim of this study was to evaluate the clinical and manometric results three different doses botulinum toxin two methods injection for treatment chronic idiopathic anal fissure.Sixty-nine patients with fissure were included in a non-randomized, prospective trial intrasphincteric toxin. All reported postdefecatory pain lasting more than months. Scoring systems developed pain, bleeding, defecatory difficulty. Maximum resting squeeze pressures determined before one month after treatment....
A prospective review of the complications ileostomy construction and takedown.One hundred twenty-seven consecutive patients undergoing a loop were included in nonrandomized computer database. Complications assessed prior to after closure. Three closure techniques performed [enterotomy suture (25.7%), resection hand sewn (31.2%) or stapled anastomosis (43.1%)] compared.One (73 male, 54 female) patients, mean age years from 1992 2002. Seventy-two underwent anterior for low rectal carcinoma, 30...
Abstract Objective Fistula‐in‐ano continues to raise problems that require important therapeutic decisions. Our aim was evaluate its recurrence and incontinence risk factors. Method We analysed a series of 279 patients who had undergone anal fistula surgery with long‐term follow‐up. Results 42.7% the fistulae were considered complex 46% been referred from other institutions. There delayed healing or in 7.2% patients, which appeared at median 4 months. The factors associated type...
Abstract BACKGROUND: Preoperative chemoradiation is becoming the standard treatment for patients with locally advanced rectal cancer. However, since introduction of total mesorectal excision (TME), local recurrence rates have been reduced significantly, and some can be spared from potentially toxic over treatment. The current study was designed to assess factors that predict in an institutional series cancer who had clinical T2 lymph node‐positive (cT2N+) tumors or cT3N0/N+ underwent radical...
Abstract BACKGROUND: High quality of surgical technique and the use descriptive measures to assess report proficiency have been shown influence locoregional tumor control in patients with rectal cancer. In this study, authors aimed audit implementation a macroscopic assessment mesorectal excision (MAME) investigate factors that influenced disease recurrence. METHODS: All curative resections for cancer were prospectively evaluated MAME between 1998 2007. Mesorectal specimens graded into 3...
BackgroundPelvic exenteration for locally advanced rectal cancer (LARC) and recurrent (LRRC) is technically challenging but increasingly performed in specialist centres. The aim of this study was to compare outcomes over time.
Abdominal perineal excision (APE) was originally described with levator ani removal for rectal cancer. An even wider, more aggressive extralevator resection APE has been proposed. Although some surgeons are performing a very wide 'extralevator (ELAPE)', there few data to recommend it routinely. This multicentre study aimed compare outcomes of and ELAPE.A propensity case-matched analysis comparing two surgical approaches (APE ELAPE) performed. All patients who underwent abdominoperineal...
Abstract Objective Patients with colorectal cancer who need a stoma should undergo preoperative marking of the site and education by trained stomatherapist. This study examined care received ostomy patients in Spanish surgery units, to assess its quality detect areas for improvement. Method A prospective was conducted twelve units Spain including visited stomatherapist after cancer. Each patient answered questionnaire about their care. Results Between September 2007 May 2008, 270 were...
Anastomotic leakage is one of the most feared complications after colonic resection. Many risk factors for anastomotic have been reported, but impact an individual surgeon as a factor has scarcely reported. The aim this study was to assess if independent in cancer surgery.This retrospective analysis prospectively collected data from patients who underwent elective resection colon with anastomosis at specialized colorectal unit January 1993 December 2010. leaks were diagnosed according...
This document outlines the important aspects of caring for patients who have been diagnosed with advanced pelvic cancer. It is primarily aimed at those are establishing a service that adequately caters to this patient group. The relevant literature has summarized and an attempt made simplify approach management these complex cases.
Real-Time Quantification in Plasma of Human Telomerase Reverse Transcriptase (hTERT) mRNA: A Simple Blood Test to Monitor Disease Cancer Patients
Adequate oxygenation is necessary for anastomotic healing, and ischemia has been found to be one of the most important factors in leakage. This study was designed assess value early postoperative intramucosal pH measurements prediction leakage patients with colorectal anastomosis.A prospective 90 rectal or sigmoid cancer primary anastomosis conducted. In all determined by using tonometry at gastric levels during first 24 48 hours postoperatively. Seven other variables also were tested...
Complex anal fistulas (CFs) are difficult to treat. Endoanal advancement flap (EAF) is one of the standard treatment options for such clinical conditions. Immediate sphincter repair after fistulectomy (ISR) not commonly performed because fear causing postoperative incontinence. The objective this study was compare results both techniques.We retrospectively analysed a prospectively entered database composed 146 patients (112 M; 34 F), undergoing operations CF cryptoglandular origin. were...
BACKGROUND: The implementation of preoperative chemoradiation combined with total mesorectal excision has reduced local recurrence rates in rectal cancer. However, the use both types treatment upper cancer is controversial. OBJECTIVE: purpose this work was to assess oncological results after radical resection cancers compared sigmoid, middle, and lower determine risk factors for DESIGN: This a retrospective analysis prospectively collected data. SETTINGS: study conducted tertiary care...