Antonio Caycedo‐Marulanda
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Diverticular Disease and Complications
- Hernia repair and management
- Surgical Simulation and Training
- Pelvic floor disorders treatments
- COVID-19 and healthcare impacts
- Enhanced Recovery After Surgery
- Climate Change and Health Impacts
- Abdominal Surgery and Complications
- Radiation Dose and Imaging
- Appendicitis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Minimally Invasive Surgical Techniques
- Colorectal Cancer Treatments and Studies
- Anesthesia and Sedative Agents
- Pelvic and Acetabular Injuries
- Esophageal Cancer Research and Treatment
- Focus Groups and Qualitative Methods
- Gastroesophageal reflux and treatments
- Hepatocellular Carcinoma Treatment and Prognosis
Health Sciences North
2017-2024
Queen's University
2020-2024
NOSM University
2017-2024
Orlando Health
2023-2024
Kingston Health Sciences Centre
2020-2023
University of Oxford
2022
Kingston General Hospital
2020-2021
Kingston University
2021
University of British Columbia
2019-2020
Queens University
2020
Organ-sparing therapy for early-stage I/IIA rectal cancer is intended to avoid functional disturbances or a permanent ostomy associated with total mesorectal excision (TME). The objective of this phase II trial was determine the outcomes and organ-sparing rate patients treated neoadjuvant chemotherapy followed by transanal surgery (TES).This included clinical T1-T3abN0 low- mid-rectal adenocarcinoma eligible endoscopic resection who were 3 months (modified folinic...
<h3>Importance</h3> Proponents of novel transanal total mesorectal excision (TME) suggest the procedure overcomes technical and oncologic challenges conventional approaches for treating rectal cancer. Recently, however, there has been controversy regarding safety procedure. <h3>Objective</h3> To assess association TME with incidence local recurrence (LR) cancer probability remaining free LR during follow-up. <h3>Design, Setting, Participants</h3> This multicenter cohort study used data from...
This document outlines the important aspects of caring for patients who have been diagnosed with advanced pelvic cancer. It is primarily aimed at those are establishing a service that adequately caters to this patient group. The relevant literature has summarized and an attempt made simplify approach management these complex cases.
Abstract Background The most important advancement in the surgical management of rectal cancer has been introduction total mesorectal excision (TME). Technical limitations to approaching mid and distal lesions remain. recently described transanal TME makes it possible minimize some difficulties by improving access. Anastomotic leak is a persistent concern after colorectal surgery no matter what technique used. objective this study was explore impact experience on incidence anastomotic TME....
Empty pelvis syndrome (EPS) is a significant source of morbidity following pelvic exenteration (PE), but undefined. EPS outcome reporting and descriptors radicality PE are inconsistent; therefore, the best approaches for prevention unknown. To facilitate future research into EPS, aim this study to define measurable core set, descriptor set written definition EPS. Consensus on strategies mitigate was also explored.
The multidisciplinary perioperative and anaesthetic management of patients undergoing pelvic exenteration is essential for good surgical outcomes. No clear guidelines have been established, there wide variation in clinical practice internationally. This consensus statement consolidates experience best collectively, systematically addresses key domains the management.The modified Delphi methodology was used to achieve from PelvEx Collaborative. process included one round online questionnaire...
Transanal minimally invasive surgery (TAMIS) has emerged as a relatively new technique in treating early cancer and benign lesion of the rectum. The is likely to be widely adopted, surpassing other comparable techniques owing its simple setup cost-effectiveness. We assessed outcomes TAMIS at our centre.We retrospectively reviewed prospectively collected data on 50 patients who underwent for benign, malignant T1 or T2 cancers that were unfit radical over 4-year period. Outcomes, including...
Abstract Introduction Transanal total mesorectal excision (taTME) is a novel approach to surgery for rectal cancer. The technique has gained significant popularity in the surgical community due promising ability overcome technical difficulties related access of distal pelvis. Recently, Norwegian surgeons issued local moratorium potential issues with safety procedure. Early adopters taTME Canada have recognized need create guidelines its adoption and supervision. objective statement provide...
A resection with clear margins (R0 resection) is the most important prognostic factor in patients locally recurrent rectal cancer (LRRC). However, this achieved only 60 per cent of patients. The aim study to investigate whether addition induction chemotherapy neoadjuvant chemo(re)irradiation improves R0 rate LRRC.This multicentre, international, open-label, phase III, parallel-arms will enrol 364 resectable LRRC after previous partial or total mesorectal without synchronous distant...
Colorectal cancer (CRC) is the second leading cause of deaths. Despite recent advances, five-year survival rates remain largely unchanged. Desorption electrospray ionization mass spectrometry imaging (DESI) an emerging nondestructive metabolomics-based method that retains spatial orientation small-molecule profiles on tissue sections, which may be validated by 'gold standard' histopathology. In this study, CRC samples were analyzed DESI from 10 patients undergoing surgery at Kingston Health...
Aims Large venous invasion (VI) is prognostically significant in colon cancer. The increased use of elastic stains by pathologists results higher VI detection rates compared to routine alone. This study assesses the prognostic value detected versus stains. Methods and Colon cancers resected between 2014 2017 underwent pathology slide review for VI. Cases without on stain were stained trichrome re‐examined. Demographic, clinical, pathological outcome data gathered retrospective review....
Abstract Background Abdominoperineal excision (APE) for rectal cancer is associated with a relatively high risk of positive margins and postoperative morbidity, particularly related to perineal wound healing problems. It unknown whether the use minimally invasive approach part these procedures can improve outcomes without oncological compromise. The aim this study was evaluate feasibility transperineal abdominoperineal (TpAPE) Methods This multicenter retrospective cohort included all...
Empty pelvis syndrome is a complex challenge resulting from the dead space generated by exenteration.A systematic review of reconstructive techniques to prevent empty cited inconsistent definitions and heterogeneous outcome reporting, was therefore unable make strong conclusions in favour particular strategy 1 .The severity complications escalates with more radical surgery as boundaries are pushed 2,3 guidelines proposed here will establish standardized definitions, outcomes, descriptors,...