Abhishek Abhishek
A5100728750- Gout, Hyperuricemia, Uric Acid
- Rheumatoid Arthritis Research and Therapies
- Osteoarthritis Treatment and Mechanisms
- Spondyloarthritis Studies and Treatments
- Case Reports on Hematomas
- Urticaria and Related Conditions
- Musculoskeletal pain and rehabilitation
- Bone and Joint Diseases
- Autoimmune and Inflammatory Disorders Research
- Alkaline Phosphatase Research Studies
- Musculoskeletal synovial abnormalities and treatments
- Systemic Lupus Erythematosus Research
- Alcohol Consumption and Health Effects
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammatory mediators and NSAID effects
- SARS-CoV-2 and COVID-19 Research
- Chronic Lymphocytic Leukemia Research
- Inflammatory Bowel Disease
- Nail Diseases and Treatments
- Total Knee Arthroplasty Outcomes
- Immunodeficiency and Autoimmune Disorders
- Liver Disease Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Plant Pathogens and Fungal Diseases
- Drug-Induced Hepatotoxicity and Protection
University of Nottingham
2016-2025
Nottingham Biomedical Research Centre
2018-2025
Indian Veterinary Research Institute
2018-2025
Amrita Vishwa Vidyapeetham
2025
Indian Institute of Technology Kanpur
2025
Center for Rheumatology
2016-2024
Versus Arthritis
2013-2024
Nottingham City Hospital
2010-2024
Nottingham University Hospitals NHS Trust
2018-2024
Society for Personality and Social Psychology
2024
BackgroundIn the UK, gout management is suboptimum, with only 40% of patients receiving urate-lowering therapy, usually without titration to achieve a target serum urate concentration. Nurses successfully manage many diseases in primary care. We compared nurse-led care usual led by general practitioners (GPs) for people community.MethodsResearch nurses were trained best practice gout, including providing individualised information and engaging shared decision making. Adults who had...
<h3>Importance</h3> Gout is associated with cardiovascular diseases. The temporal association between gout flares and events has not been investigated. <h3>Objective</h3> To investigate whether there a transient increase in risk of after recent flare. <h3>Design, Setting, Participants</h3> A retrospective observational study was conducted using electronic health records from the Clinical Practice Research Datalink England January 1, 1997, December 31, 2020. multivariable nested case-control...
BackgroundImmunosuppressive treatments inhibit vaccine-induced immunity against SARS-CoV-2. We evaluated whether a 2-week interruption of methotrexate treatment immediately after the COVID-19 vaccine booster improved antibody responses S1 receptor-binding domain (S1-RBD) SARS-CoV-2 spike protein compared with uninterrupted in patients immune-mediated inflammatory diseases.MethodsWe did an open-label, prospective, two-arm, parallel-group, multicentre, randomised, controlled, superiority trial...
Objective Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) EULAR have developed the first‐ever CPPD disease. Methods Supported by ACR EULAR, a multinational group investigators followed established methodology to develop these criteria. generated lists candidate items refined their definitions, collected de‐identified patient...
To formulate evidence-based recommendations and overarching principles on the use of imaging in clinical management crystal-induced arthropathies (CiAs).
The objectives of this study were to examine changes in the incidence and prevalence RA between 1990 2014 explore if there is any geographic variation UK.This was a primary care-based prospective cohort study. People contributing acceptable data Clinical Practice Research Datalink 1 January 31 December included. Read codes used identify cases ⩾18 years age. rates for each year standardized population regional overall population.The 3.81/10 000 person-years 0.67%, respectively, 2014. annual...
<h3>Objective</h3> There is a lack of standardisation in the terminology used to describe gout. The aim this project was develop consensus statement describing recommended nomenclature for disease states <h3>Methods</h3> A content analysis gout-related articles from rheumatology and general internal medicine journals published over 5-year period identified potential labels commonly assigned them. Based on these findings, experts gout were invited participate Delphi exercise face-to-face...
<h3>Importance</h3> Osteoarthritis is a prevalent, debilitating, and costly chronic disease for which recommended first-line treatment underused. <h3>Objective</h3> To compare the effect of an internet-based knee osteoarthritis vs routine self-management (ie, usual care). <h3>Design, Setting, Participants</h3> This randomized clinical trial was conducted from October 2018 to March 2020. Participants included individuals aged 45 years or older with diagnosis recruited existing primary care...
To estimate the incidence, prevalence, and survival of systemic sclerosis in United Kingdom. We conducted a historical cohort study using data from Clinical Practice Research Datalink (CPRD). calculated incidence between 1994 2013 examined its association with age, sex, socioeconomic status. point prevalence on 1 July same exposures. identified 1327 cases incident sclerosis. Annual was 19.4 per million person-years 2013. The 4.7 times higher women than men, not influenced by status, has...
To develop definitions for imaging features being considered as potential classification criteria calcium pyrophosphate deposition (CPPD) disease, additional to clinical and laboratory criteria, compile example images of CPPD on different modalities.
Calcium pyrophosphate deposition (CPPD) disease is prevalent and has diverse presentations, but there are no validated classification criteria for this symptomatic arthritis. The American College of Rheumatology (ACR) EULAR have developed the first-ever CPPD disease.Supported by ACR EULAR, a multinational group investigators followed established methodology to develop these criteria. generated lists candidate items refined their definitions, collected de-identified patient profiles,...
BackgroundThe risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated in around 5% patients, which led to intensive monitoring strategies. However, the evidence is derived retrospective studies that underreported factors disease. We evaluated long-term MTX therapy on a longitudinal cohort study using two non-invasive markers.MethodBetween 2014-2021, adult patients diagnosed with Rheumatoid Arthritis (RA) or psoriasis for ≥2 years were recruited...
To assess if smoking status at the time of commencing an anti-TNF-alpha agent for rheumatoid arthritis (RA) reduces likelihood achieving least a moderate response on European League Against Rheumatism (EULAR) criteria 3-month assessment.All patients with RA treated their first Department Rheumatology, Derby Hospital NHS Trust between April 2001 and October 2008 were included in this retrospective case control study. Information about age, gender, disease duration, body mass index, (current...