A5054581304- Iron Metabolism and Disorders
- Folate and B Vitamins Research
- Hemoglobinopathies and Related Disorders
- Retinal Imaging and Analysis
- Peroxisome Proliferator-Activated Receptors
- Organ Transplantation Techniques and Outcomes
- Retinal Diseases and Treatments
- Porphyrin Metabolism and Disorders
- Retinoids in leukemia and cellular processes
- Organ Donation and Transplantation
- Cardiovascular Disease and Adiposity
- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Mycobacterium research and diagnosis
- T-cell and B-cell Immunology
- Advanced Glycation End Products research
- Cardiovascular Health and Disease Prevention
- Monoclonal and Polyclonal Antibodies Research
- Liver Disease and Transplantation
- Renal and Vascular Pathologies
- Cell Adhesion Molecules Research
- Blood Pressure and Hypertension Studies
Ludwig-Maximilians-Universität München
2021
Helmholtz Zentrum München
2021
Zimmer Biomet (Germany)
2021
University of Freiburg
2019
Paragon (Greece)
2010
Brigham and Women's Hospital
2010
Harvard University
2010
University of Cambridge
2004
Background Nuclear hormone receptors are important in the regulation of epidermal differentiation and have been implicated lipid metabolism. In particular, there is evidence suggesting that activation peroxisome proliferator‐activated (PPARs) an factor sebocyte lipogenesis. Objectives To determine role PPARs, farnesoid X receptor (FXR) other orphan nuclear sebaceous gland function vitro by investigating biochemical effects appropriate ligands, establishing RNA protein expression patterns a...
Microvascular alterations play a key role in the development of diabetes complications. Retinal vessel analysis is unique method to examine microvascular changes brain-derived vessels.Sixty-seven pediatric and adolescent type 1 patients 58 healthy control persons (mean age 12.4 ± 2.9 years) underwent non-mydriatic retinal photography both eyes. Central arteriolar central venular (CRVE) diameter equivalents as well arteriolar-to-venular ratio were calculated using semiautomated software. All...
Iron-related disorders of the liver can result in serious health conditions, such as cirrhosis. Evidence on role modifiable lifestyle factors like nutrition iron storage is lacking. Thus, we aimed to assess association habitual diet with content (LIC). We investigated 303 participants from population-based KORA-MRI study who underwent whole-body magnetic resonance imaging (MRI). Dietary habits were evaluated using repeated 24 h food lists and a frequency questionnaire. Sex-stratified...
Hepatic iron overload can cause severe organ damage; therefore, an early diagnosis and the identification of potential risk factors is crucial. We aimed to investigate sex-specific distribution hepatic content (HIC) in a population-based cohort identify relevant associated from panel markers. analyzed N = 353 participants cross-sectional sample (KORA FF4) who underwent whole-body magnetic resonance imaging. HIC was assessed by single-voxel spectroscopy with high-speed T2-corrected multi-echo...
Abstract Context Hepatic iron overload can cause severe organ damage. Therefore, an early diagnosis is crucial, and identification of modifiable risk factors could help to prevent manifestations iron-driven complications. Objective To investigate the sex-specific distribution hepatic content (HIC) in a population-based sample, identify relevant associated from panel markers. Methods We analysed N=353 participants cross-sectional, cohort Southern Germany (KORA FF4) who underwent whole-body...