A5014931185- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Health and Medical Studies
- Medical and Health Sciences Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Dermatologic Treatments and Research
- Health Systems, Economic Evaluations, Quality of Life
- Coronary Interventions and Diagnostics
- Digitalization, Law, and Regulation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Peripheral Artery Disease Management
- Long-Term Effects of COVID-19
- Infective Endocarditis Diagnosis and Management
- Clinical practice guidelines implementation
- Diagnosis and Treatment of Venous Diseases
- Acute Myocardial Infarction Research
- Ultrasound in Clinical Applications
- Clinical Laboratory Practices and Quality Control
Orthopädische Praxis
2014-2025
Vivantes Klinikum
2024
Berlin Heart (Germany)
2024
Center for HIV and Hepatogastroenterology
2024
Shanghai Institute of Hematology
2023
Brandenburg University of Technology Cottbus-Senftenberg
2015-2021
TU Dresden
2008-2020
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2009-2020
Janssen (United States)
2016
Catholic University of Applied Sciences
2013
Implantable cardioverter-defibrillators (ICDs) prevent sudden death from cardiac causes in selected patients but require the use of transvenous lead systems. To eliminate need for venous access, we designed and tested an entirely subcutaneous ICD system.First, conducted two short-term clinical trials to identify a suitable device configuration assess energy requirements. We evaluated four configurations 78 who were candidates implantation subsequently best 49 additional determine...
AimsTo evaluate the safety, efficacy, and performance of TriGuard™ HDH Embolic Deflection Device (TriGuard) compared with no cerebral protection in patients undergoing transcatheter aortic valve implantation (TAVI).
Background— This prospective, multicenter study sought to evaluate the incidence of asymptomatic cerebral emboli (ACE) during ablation atrial fibrillation (AF) using a multielectrode radiofrequency (MER) system when specific procedural changes were applied. Methods and Results— Sixty subjects (age 60±10 years; 87% paroxysmal; CHADS 2 score, 0.6±0.7) undergoing AF with circular MER catheter studied. Three specified: (1) was performed under therapeutic vitamin K antagonist heparin maintain...
Abstract Aims To evaluate the effectiveness and safety of cryoballoon ablation (CBA) compared with radiofrequency (RFA) for symptomatic paroxysmal or drug-refractory persistent atrial fibrillation (AF). Methods results Prospective cluster cohort study in experienced CBA RFA centres. Primary endpoint was ‘atrial arrhythmia recurrence’, secondary endpoints were as follows: procedural results, safety, clinical course. A total 4189 patients included: 2329 (55.6%) 1860 (44.4%). Cryoballoon...
To analyse outcomes of supraventricular tachycardia (SVT) ablations performed within a prospective German Ablation Quality Registry.Data from 12 566 patients who underwent catheter ablation SVT between January 2007 and 2010 to treat atrial fibrillation (AFIB, 37.2% procedures), flutter (AFL, 29.9%), atrioventricular nodal re-entrant (AVNRT, 23.2%), (6.3%), focal (AT, 3.4%) were prospectively collected. Patients followed for at least 1 year. The periprocedural success rate was 96.3%, ranging...
Patients with nonvalvular atrial fibrillation and prior stroke or transient ischemic attack (TIA) are at high risk for recurrent stroke. We investigated whether ximelagatran was noninferior to warfarin in patients TIA.We analyzed pooled data from the SPORTIF III V trials stroke/TIA. The primary outcome composite annual rate of both hemorrhagic strokes systemic embolic events. Secondary analyses considered separately, bleeding, nonrandomized, concomitant therapy aspirin < =100 mg/d.Patients...
AimsThis prospective, multicentre study (PRECISION GOLD) evaluated the incidence of asymptomatic cerebral embolism (ACE) after pulmonary vein isolation (PVI) using a new gold multi-electrode radiofrequency (RF) ablation catheter, catheter (PVAC) GOLD. Also, procedural efficiency PVAC GOLD was compared with ERACE. The ERACE demonstrated that low ACE can be achieved platinum RF combined manoeuvres to reduce emboli.
FIRM Ablation Outcomes for Recurrent Nonparoxysmal AF Introduction A patient‐tailored ablation approach focused on the elimination of both pulmonary vein triggers as well substrate drivers may result in favorable outcomes recurrent persistent patients. Objective We evaluated long‐term rotor combined with conventional isolation (PVI) patients nonparoxysmal AF. Methods Fifty‐eight consecutive underwent FIRM‐guided followed by PVI treatment software algorithm was used to display rotational...
Hintergrund Für die medizinische Behandlung des Post-COVID-19-Syndroms werden derzeit nur vereinzelt sektorenübergreifende ärztliche Behandlungsnetzwerke, wie bspw. das Post-COVIDLMU-KONZEPT [1], umgesetzt. Verbindlich kann jedoch keine kausale Therapie nach evidenzbasierten Kriterien empfohlen werden. Inauguriert wird für Post-COVID-19 ein sektorenübergreifendes ärztlich geleitetes Behandlungsmanagement, zunächst auf Schwerpunktsyndromatik Fatigue/Immunometabolische Depression (als Target...
Concomitant microwave ablation for curative treatment of atrial fibrillation (AF) was performed in 18 patients with history chronic and indication open heart surgery, 11 mitral valve replacement 7 coronary artery bypass grafting. There were no perioperative complications. During the postoperative period most had intermittent AF, they received low dose Sotalol therapy electric cardio-versions. Up to now seven have reached follow-up day 90. One patient has persistent AF. Two typical flutter...
Age‐Related Complication Rates in AF Ablation Introduction Despite a rising demand for catheter ablation (CA) of atrial fibrillation (AF) an elderly population, complication and success rates are not fully elucidated. We sought to compare CA patients ≥75 versus <75 years age. Methods Results Patients with symptomatic, drug‐refractory were prospectively enrolled from January 2007 2010 this multicenter study. A total 4,449 patients, group 1 2 (n = 227, age 77.3 ± 2.2 vs. 59.7 9.8 years,...
Abstract Background Pulmonary vein isolation (PVI) is recommended to treat paroxysmal and persistent atrial fibrillation (AF). This analysis aimed assess the hospital efficiency of single-shot cryoballoon ablation (CBA) point-by-point radiofrequency (RFA). Methods The discrete event simulation used PVI procedure times from FREEZE Cohort study establish electrophysiology (EP) lab occupancy time. 1000 EP days were simulated according an illustrative German hospital, including 3 cases per day...
Objective of the present study was to compare VARC-2 access and bleeding complications a complete percutaneous versus surgical cut-down approach for transfemoral TAVI "in real world-all comers" setting.The ideal is still part lively debate. Until today, none available techniques superiority could be demonstrated. The adds considerable number patients experience.The included 334 consecutive patients, including 199 in 135 group. Mean patient's age 81.4 ± 4.6. Calculated logistic EuroSCORE...
Catheter ablation (CA) has emerged as a widespread therapeutic option in the treatment of atrial fibrillation (AF). Currently, no safety data with regard to impact underlying structural heart diseases (SHD) are available. We sought assess risk for acute and long-term complications during CA AF relation SHD.We included 6,211 patients prospective registry undergoing 41 nationwide centers. All were divided into 4 groups according disease: No SHD (69.4%), hypertensive disease (HHD) (12.0%),...
PURPOSE, MATERIAL AND METHODS: Microcirculatory disturbances may be responsible for some of the adverse effects induced by contrast media. The influence iopromide 370 (Ultravist) on cutaneous microcirculation was therefore investigated in 15 patients a prospective study. Twenty ml and 20 0.9% NaCl were injected as reference subclavian artery at beginning diagnostic coronary angiography. Erythrocyte velocity measured ipsilateral nailfold capillaries of, during, after injection continuously up...
Objective: To compare the real-world effectiveness and safety of non-vitamin-K-antagonist oral anticoagulant (NOAC) treatment in atrial fibrillation (AF) patients with a vitamin-K-antagonist (VKA)-based treatment. Methods: This was retrospective analysis an anonymized claims dataset from 3 German health insurance funds covering period January 01, 2010 to June 30, 2014, minimum observation time 12 months. All continuously insured at least 2 outpatient AF diagnoses and/or 1 inpatient...