A5086836093- Digital literacy in education
- Educational Innovations and Technology
- Mobile Learning in Education
- E-Learning and Knowledge Management
- Virus-based gene therapy research
- Child Development and Digital Technology
- Metabolism, Diabetes, and Cancer
- Education and Digital Technologies
- Pancreatic function and diabetes
- Antifungal resistance and susceptibility
- Literacy and Educational Practices
- Cell Adhesion Molecules Research
- Parvovirus B19 Infection Studies
- Cancer, Hypoxia, and Metabolism
- Protease and Inhibitor Mechanisms
- Animal Virus Infections Studies
- Educational Games and Gamification
- S100 Proteins and Annexins
- Fungal and yeast genetics research
- Higher Education Teaching and Evaluation
- Bullying, Victimization, and Aggression
- Innovative Approaches in Technology and Social Development
- Viral Infections and Immunology Research
- Smart Cities and Technologies
- Gender and Technology in Education
Universidade de Vigo
2015-2025
Centro de Biología Molecular Severo Ochoa
2019-2023
Universidad Autónoma de Madrid
2000-2023
Universidad Univer
2020
Colciencias
2016
Universidad Autónoma Metropolitana
2012-2015
Consejo Superior de Investigaciones Científicas
2002-2012
Northwestern University
2010-2011
Instituto de Investigaciones Biomédicas Sols-Morreale
2004
Centro Nacional de Biotecnología
2001-2002
Environmental education, at least in northwest Spain, is often overlooked the education system from infant schooling onwards and interventions are needed to raise profile of this subject. The aim study was examine impact a learning program designed for primary school students broaden their ecological awareness improve digital literacy using gamification tools. research developed qualitative approach, with data obtained 156 subjects, including teachers, families. results show that children...
In general, young people, and adolescents under protective measures, do not have the digital competence autonomy necessary to successfully interact with public administrations. Children right quality education that promotes listening, participation, equal access opportunities, especially in age. However, this remains a global challenge cannot be waived. For reason, main objective of study is know impact implementation Participatory Action Research (PAR) project carried out people living four...
Artificial Intelligence (AI) is currently transforming many areas of society, including education. AI offers innovative tools and methods that personalise learning, automate processes improve the educational experience. Social education seeks to foster integral human development collective well-being, can be a powerful tool achieve these goals. For this reason, main objective study learn about use by future social educators. This research approached from qualitative methodology. A total 69...
Metastatic melanoma cells are highly adaptable to their in vivo microenvironment and can switch between protease-dependent mesenchymal protease-independent amoeboid invasion facilitate metastasis. Such adaptability be visualized vitro, when cultured conditions that recapitulate three-dimensional microenvironments. Using thick collagen layers cell culture extravasation assays, we found pigment epithelium-derived factor (PEDF) suppressed lung of aggressive by coordinated regulation shape...
Candida albicans is able to respond environmental changes by inducing a distinct morphological program, which related the ability infect mammalian hosts. Although some of signal transduction pathways involved in this response are known, it not clear how signals sensed and transmitted these cascades. In work, we have studied function GPA2, new gene from C. albicans, encodes G-protein alpha-subunit homologue. We demonstrate that Gpa2 plays an important role yeast-hypha dimorphic transition...
In the spherical virion of parvovirus minute virus mice, several amino acid side chains capsid were previously found to be involved in interactions with viral single-stranded DNA molecule. We have individually truncated by mutation alanine many (ten) these and analyzed effects on assembly, stability conformation, encapsidation, infectivity. Mutation residues Tyr-270, Asp-273, or Asp-474 led a drastic reduction Mutant Y270A was defective assembly; mutant D273A formed stable capsids, but it...
Abstract Background Antimicrobial stewardship programs (ASPs) are recommended in nursing homes (NHs), although data limited. We aimed to determine the clinical and ecological impact of an ASP for NHs. Methods performed a cluster, randomized, controlled trial before–after study with interrupted time-series analyses 14 NHs 30 consecutive months from July 2018 December 2020 Andalusia, Spain. Seven facilities implemented bundle 5 educational measures (general ASP) 7 added 1-to-1 interviews...
It is important for teens during adolescence to plan conscientiously their vital route gradually strengthen academic and career aspirations, this must be known by teachers progenitors.The aim of paper discover the working preferences students in final year compulsory education Spain.The investigation was developed through qualitative analysis multiple case studies.As results conclusions, it should noted that differences gender were detected regarding inclination shown towards experimental...
Systematic deletions and point mutations in the C-terminal extension of mammalian PFK (phosphofructokinase) led us to identify Leu-767 Glu-768 M-type isoform (PFK-M) as motifs responsible for role this region inhibition by MgATP. These amino acids are only residues C-terminus that conserved all isoforms, were found have a similar function C-type isoenzyme. Both PFK-C PFK-M also observed be critical citrate, which is synergistic with Binding studies utilizing titration intrinsic protein...
Resumen:La gran transformación social que ha generado el desarrollo y la expansión de las TIC comienza también a irradiar ámbito educativo, una vez se han incorporado nuevos dispositivos al proceso aprendizaje.Por ello, objetivo este trabajo es proporcionar un panorama global actualizado del estado cuestión, partir revisión literatura científica, sobre uso los cambios atribuibles tableta en alumnado educación primaria.El estudio realizado aborda desde metodología esencialmente cualitativa,...
Pigment epithelium-derived factor (PEDF) is a broad-spectrum angiogenesis inhibitor that displays potent antimetastatic activity in multiple tumor types. We have previously shown PEDF prevents primary growth and metastatic spread of human melanoma mouse experimental models. Consistent with these observations, expression lost at the late stages progression, allowing cells to become angiogenic, migratory, invasive. PEDF's ability modify interplay between host tissues strongly supports its use...
The existence of studies that support the usefulness tablets in primary education is encouraging. For this reason, research analyses device's didactic use. present project part a qualitative narrative research. data experiences supported by tablet were collected through nine discussion groups and set observation techniques (with 76 students aged between 6 11). It concluded are not used systematically education. Spanish language literature subjects where most, although it also mathematics to...
Information and Communication Technologies are now a common feature in classroom activities. The aim of this study was to present praxis developed for the tablet use by primary education students (aged 6-12) studying natural sciences mathematics. This research is qualitative follows narrative-ethnographic approach. sample consisted 120 52 educational blogs. results conclusions reveal that rarely innovative or ludic. bulk tablet-based activities were classes rather than mathematics, most...
Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N‐ and C‐terminal halves of mammalian M‐ C‐type isozymes, to investigate contribution each terminus catalytic site fructose‐2,6‐P 2 /fructose‐1,6‐P allosteric site. The homogeneously‐purified chimeric enzymes organized into tetramers, exhibited kinetic properties for fructose‐6‐P MgATP similar those native enzyme that furnished N‐terminal domain in case, whereas their activatory characteristics coincided with isozyme...
As many tumor cells synthetize vascular endothelial growth factors (VEGF) that promote neo-vascularization and metastasis, frontline cancer therapies often administer anti-VEGF (α-VEGF) antibodies. To target the oncolytic parvovirus minute virus of mice (MVM) to vasculature, we studied functional tolerance, evasion neutralization, induction α-VEGF antibodies chimeric viruses in which footprint a neutralizing monoclonal antibody within 3-fold capsid spike was replaced by VEGF-blocking...
La influenciada de las TIC es notoria en todos los ámbitos y su utilización también se lleva incrementado el contexto familiar escolar. Por ello, objetivo central este trabajo analizar conocer posicionamiento la familia, concretamente padres-madres, integración tableta digital alumnado Educación Primaria. presente investigación encuadra metodología cualitativa, para ello ha abordado un estudio casos múltiples, a partir recogida narrativas progenitores del cuatro centros educativos situados...
The press is often attributed with little credibility, and the recent phenomenon of fake news has put it under spotlight once again. As a result, objective this study to discover margin veracity versus falsehood reports on tablets in primary education published digital newspapers. This qualitative been developed basis an analysis 120 items Spanish conclusions show that topic correspond reality can be considered credible since they are line results provided scientific literature....
The problems that arise with coexistence between schoolchildren are a challenge when it comes to carrying out the teaching–learning process. In recent years, presence of bullying has increased in schools. aim this study is identify perceptions teachers regarding among schoolchildren, more specifically concerning bullying, as well their position prevention bullying. Research was carried using mixed approach. A total 225 education professionals from different schools Spain took part. From...
El alumnado de las aulas hospitalarias presenta características especiales, al tratarse niños/as enfermos/as, forma temporal o crónica. Por este motivo es fundamental atender a su estado físico y psicológico. Las TIC pueden resultar un instrumento muy útil para trabajar con ellos/as, tanto nivel educativo como emocional. La presente investigación establece objetivo general descubrir la percepción del profesorado, sus familias acerca uso en el aula hospitalaria, así hacer una comparativa...
Las dotaciones tecnológicas con las que cuentan instituciones manifiestan cierta preocupación y voluntad por promover, desde la escuela, incorporación de los avances digitales. De hecho, en actualidad diversos centros nuestra Comunidad, así como otros del resto Estado llevan a cabo implantación distintas experiencias tabletas el entorno escolar, integrándolas además currículo. Estos dispositivos ya se están utilizando múltiples situaciones espacios, forma cotidiana. Entre digitales ,...