Harri Isokuortti

ORCID: 0000-0002-1776-1944
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About
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Research Areas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traumatic Brain Injury Research
  • Cardiac Arrest and Resuscitation
  • Trauma and Emergency Care Studies
  • Research in Social Sciences
  • Neurosurgical Procedures and Complications
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Migraine and Headache Studies
  • Cerebrospinal fluid and hydrocephalus
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Musculoskeletal pain and rehabilitation
  • Spinal Fractures and Fixation Techniques
  • Respiratory Support and Mechanisms
  • Healthcare professionals’ stress and burnout
  • Radiation Dose and Imaging
  • Acute Ischemic Stroke Management

University of Helsinki
2014-2024

Helsinki University Hospital
2020-2024

Päivikki and Sakari Sohlberg Foundation
2021

Tampere University
2015-2018

OBJECTIVEThe incidence of intracranial abnormalities after mild traumatic brain injury (TBI) varies widely across studies. This study describes the characteristics (acute/preexisting) in a large representative sample head-injured patients who underwent CT imaging an emergency department.METHODSCT scans were systematically analyzed/coded TBI Common Data Elements framework. Logistic regression modeling was used to quantify risk factors for with TBIs. cohort included all treated at department...

10.3171/2017.7.jns17615 article EN Journal of neurosurgery 2018-01-12

Mild traumatic brain injury (mTBI) is a public health problem. Outcome from mTBI heterogeneous in part due to pre-injury individual differences that typically are not well described or understood. Pre-injury characteristics of all consecutive patients (n=3023) who underwent head computed tomography acute trauma the emergency department Tampere University Hospital, Finland, between August 2010 and July 2012 were examined. Patients screened obtain sample working age adults with no medical...

10.1089/neu.2015.3888 article EN Journal of Neurotrauma 2015-06-09

Post-traumatic headache (PTH) is a common symptom following mild traumatic brain injury (mTBI). Patients at risk to develop acute PTH (aPTH) and further persistent (pPTH) need be recognized.This one-year follow-up of 127 patients with mTBI, aged 18 68, referred outpatient clinic in the Helsinki University Hospital. Symptoms were assessed emergency department (ED), structured interview visit Rivermead post-concussion questionnaire one, three, 12 months after injury. Psychiatric disorders...

10.1186/s10194-022-01398-9 article EN cc-by The Journal of Headache and Pain 2022-02-19

The objective was to determine the incidence of surgically treated chronic subdural hematoma (cSDH) within six months after head trauma in a consecutive series injury patients with normal initial computed tomography (CT). A total 1941 adult injuries who underwent CT 48 h and were at Tampere University Hospital's emergency department retrospectively evaluated from medical records (median age = 59 years, IQR 39-79 males 58%, using antithrombotic medication 26%). Patients no signs acute...

10.1007/s00701-024-06040-y article EN cc-by Acta Neurochirurgica 2024-03-22

AimThe purpose of this study is to document the annual incidence and trends pediatric traumatic brain injury (pTBI) in Finland over course 21 years.MethodsWe conducted a retrospective nationwide register-based cohort used Finnish Care Register Population information statistics from 1998 2018. The patient group includes all patients aged <18 at time injury. We included emergency department (ED) visits subsequent inpatient admissions (meaning least one night hospital) with International...

10.1016/j.injury.2022.12.023 article EN cc-by Injury 2022-12-19

The outcome of patients with acute ischemic stroke who require mechanical ventilation has been poor. Intubation due to a reversible condition could be associated better 1-year survival.All adult treated in Helsinki University Hospital 2016-2020 were admitted because an (either or thrombosis seen on imaging) and needed included this retrospective cohort study. Data demographics, medical history, index stroke, indication for intubation collected. primary was mortality. Secondary outcomes...

10.1007/s12028-023-01674-9 article EN cc-by Neurocritical Care 2023-02-09

Abstract Background Post-traumatic hydrocephalus (PTH) is a well-known complication of head injury. The percentage patients experiencing PTH in trauma cohorts (0.7–51.4%) varies greatly the prior literature depending on study population and applied diagnostic criteria. objective was to determine incidence surgically treated consecutive series undergoing acute computed tomography (CT) following Methods All ( N = 2908) with injuries who underwent CT were at Tampere University Hospital’s...

10.1007/s00701-022-05299-3 article EN cc-by Acta Neurochirurgica 2022-07-07

Objective This study examined the prevalence of preexisting conditions that could affect premorbid brain health, cognition, and functional independence among older adults with mild traumatic injury (MTBI), relationship between conditions, characteristics, emergency department (ED) discharge location (home versus continued care).Methods Older (N = 1,427; 55–104 years-old; 47.4% men) who underwent head computed tomography (CT) after acute trauma were recruited from ED. Researchers documented...

10.1080/02699052.2021.1976419 article EN Brain Injury 2021-09-21

To examine perceived injustice and its associations with self-reported symptoms return to work at 3 months after injury in a prospectively recruited sample of patients mild traumatic brain (mTBI).Observational study.TBI outpatient unit.Adult aged 18 68 years mTBI (n = 100) or orthopedic ([OI]; n 34).The Injustice Experience Questionnaire (IEQ) the Rivermead Post Concussion (RPQ), Beck Depression Inventory-Second Edition (BDI-II), PTSD Checklist-Civilian Version (PCL-C), Pain Visual Analog...

10.1097/htr.0000000000000698 article EN Journal of Head Trauma Rehabilitation 2021-06-15

Background: Serotonergic antidepressants may predispose to bleeding but the effect on traumatic intracranial is unknown. Methods: The rate of in patients with antidepressant medication was compared not a cohort acute head injury. This association examined by using consecutive trauma from Finnish tertiary center emergency department (Tampere University Hospital, Tampere, Finland). All (2010-2012) adult (n = 2,890; median age 58; male 56%, CT-positive 22%, antithrombotic users 25%, 10%) who...

10.3389/fneur.2021.758707 article EN cc-by Frontiers in Neurology 2021-10-28

Background: We evaluated the prevalence of psychiatric disorders in mild traumatic brain injury (MTBI) patients and investigated comorbidity relation to subjective symptoms return work (RTW). Methods: recruited 103 MTBI (mean age 40.8 years, SD 3.1) prospectively from University Hospital. The were followed up for one year. Rivermead Post-Concussion Symptom Questionnaire (RPQ) Extended Glasgow Outcome Scale (GOSE) administered month after MTBI. Three months MTBI, any assessed using Structured...

10.3390/brainsci10120916 article EN cc-by Brain Sciences 2020-11-27

Background Serotonergic antidepressants may predispose to bleeding, but little is known of the risk for traumatic intracranial bleeding. Methods This was a prospective case-control study 218 patients with mild brain injuries (TBI) who were treated at Finnish tertiary trauma hospital. Injury-related information and clinical findings prospectively collected in emergency department. Detailed pre-injury health history from electronic medical records. Information on use serotonergic attained...

10.3389/fneur.2022.952188 article EN cc-by Frontiers in Neurology 2022-12-07

The main objective of this prospective cohort study was to evaluate whether traumatic microbleeds (TMBs) are a significant prognostic factor return work (RTW), post-traumatic symptoms, and overall recovery in patients with mild brain injury (mTBI). One hundred thirteen mTBI were recruited from the Helsinki University Hospital emergency units. All underwent multi-contrast 3T magnetic resonance imaging (MRI) 3-17 days after mTBI. Patients evaluated Traumatic Brain Injury Outpatient Clinic 1...

10.1089/neu.2021.0055 article EN Journal of Neurotrauma 2021-04-13

Abstract Objective: To examine the associations between recent stressful life events and self-reported fatigue depressive symptoms in patients with mild traumatic brain injury. Design: Observational cohort study. Participants: Patients (aged 18–68 years) injury (n = 99) or lower extremity orthopaedic 34). Methods: Data on were collected 3 months post-injury. Stressful last 12 assessed as part of a structured interview using checklist 11 common events, Barrow Neurological Institute Fatigue...

10.2340/jrm.v56.13438 article EN cc-by-nc Journal of Rehabilitation Medicine 2024-03-04

Abstract Background Return to work (RTW) might be delayed in patients with complicated mild traumatic brain injury (MTBI), i.e., MTBI associated intracranial lesions. However, the effect of different types lesions on RTW has not studied before. We investigated whether detected by CT and MRI are return post-concussion symptoms MTBI. Methods prospectively followed up 113 adult that underwent a within 3–17 days after injury. was assessed one-day accuracy one year Rivermead Post-Concussion...

10.1007/s00701-022-05244-4 article EN cc-by Acta Neurochirurgica 2022-05-31

Abstract Objective Preexisting health conditions are associated with worse outcome following mild traumatic brain injury (MTBI), which is especially important in MTBI management among older adults. This study focused on adults who presented to an emergency department (ED) uncomplicated MTBI, examining the relationship between clinical signs of preexisting conditions, and location ED discharge. Method Participants included (n = 616, men 44.8%, ≥55 years-old) Tampere University Hospital (GCS...

10.1093/arclin/acaa067.04 article EN Archives of Clinical Neuropsychology 2020-08-28

Abstract Background: Post-traumatic headache (PTH) is a common symptom following mild traumatic brain injury (mTBI). Patients at risk to develop acute PTH (aPTH) and further persistent (pPTH) need be recognized. Methods: This one-year follow-up of 127 patients with mTBI, aged 18 68, referred outpatient clinic in the Helsinki University Hospital. Symptoms were assessed emergency department (ED), structured interview visit Rivermead post-concussion questionnaire one, three, 12 months after...

10.21203/rs.3.rs-1117390/v1 preprint EN cc-by Research Square (Research Square) 2021-12-08
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