As an important part of power system, transformer plays irreplaceable role in the process transmission. Diagnosis transformer's failure is significance to maintain its safe and stable operation. Frequency response analysis (FRA) has been widely accepted as effective tool for winding deformation fault diagnosis, which one common failures transformers. However, there no standard reliable code FRA interpretation so far. In this paper, support vector machine (SVM) combined with diagnose faults....

Objective: To minimize the effect of muscle contractions during irreversible electroporation (IRE), this paper attempts to research ablation and by applying high-frequency IRE (H-FIRE) liver tissue in vivo. Methods: An insulated needle electrode was produced painting an insulating coating on outer surface tip. A series experiments were conducted using electrodes traditional apply H-FIRE pulses monopolar rabbit tissues. The finite element model established determine lethal thresholds Muscle...

Frequency response analysis (FRA) has recently been developed as a widely accepted tool for power transformer winding mechanical deformation diagnosis, and proven to be effective powerful in many cases. However, there still exist problems regarding the application of FRA. FRA is comparative method which measured signature should compared with its fingerprint. Small differences signatures certain frequency bands might produced by external disturbance, hinders fault diagnosis. Additionally,...

Irreversible electroporation, as a nonthermal therapy of prostate cancer, has been used in clinic for several years. The mechanism irreversible electroporation ablation is thermal independent; thus, the main structures (eg, rectum, urethra, and neurovascular bundle) are spared during treatment, which leads to retention function. However, various clinical trials have shown that muscle contractions occur this therapy, warrants deep anesthesia. Use high-frequency bipolar pulses proposed reduce...

For irreversible-electroporation (IRE)-based therapies, the underlying electric field distribution in target tissue is influenced by electroporation-induced conductivity changes and important for predicting treatment zone. Objective: In this study, we characterized liver during high-frequency irreversible electroporation (H-FIRE) treatments of widths 5 10 μs proposed a method ablation zones. Methods: To achieve this, created finite-element model treated with H-FIRE IRE pulses based on...

High-frequency bipolar high-voltage pulsed electric field can be used in tumor ablation to uniform the distribution ablated region and inhibit muscle contraction effectively. Developing a high-frequency power generator (HBPPG) with wide range of specifications, such as voltage magnitude, waveform, repetition rate, pulsewidth, is great significance for promoting clinical application irreversible electroporation. Hence, this article, novel modular HBPPG circuit topology proposed application....

Abstract The mechanisms of cell death due to electroporation are still not well understood. Recent studies suggest that is an immediate all-or-nothing response but rather a dynamic process occurs over prolonged period time. To investigate whether the dynamics depends on pulse parameters or lines, we exposed different lines pulses [monopolar millisecond, microsecond, nanosecond, and high-frequency bipolar (HFIRE)] then assessed viability at times using assays. was observed by changes in...

Transformer winding deformation is common among all sorts of transformer failures. Cumulative can eventually burgeon into catastrophic faults and result in entire network outage. It possible to detect the early signs with continuous online monitoring transformer. However, frequency response analysis (FRA) considered be a useful accurate tool for sufficient detection. This paper aims at proposing novel diagnostic system power based on FRA. In order realize winding, uses capacitive coupling...

Glioblastoma (GBM) is the deadliest type of cancer and current clinical treatments for malignant gliomas have many side effects. The article discusses possibility that nanosecond pulsed electric fields (nsPEFs) can be focused on tumors local killing. As well as utilizing CANCAN (canceled bipolar) effect to reduce neurostimulation thus overcome effects such seizures edema. In this paper, we use cell ablation viability experiments investigated BPC (Bipolar cancellation) U87-MG cells under...

ABSTRACT The impulse frequency response method is often combined with the transformer winding equivalent circuit to jointly analyse mechanism of and state, while modelling necessary fundamental work. Therefore, this paper proposes a new approach modelling. Firstly, based on design parameters transformer, finite element model constructed using ANSYS Maxwell simulation software used calculate capacitance, inductance, resistance winding. Secondly, not only considers capacitance effect between...

A bipolar pulse has been proved to be more advanced in the treatment of tumor because elimination muscle contractions and effect for ablating nonuniform tissue. In this paper, a new type modular pulsed-power generator based on Marx with double power charging is proposed. The concept two series capacitors parallel by sources, respectively, then connecting through solid-state switches different control strategies. Utilizing number fast switches, can connected polarities, so that positive or...

Pulsed electric fields have recently been the focus of considerable attention because their potential application in biomedicine. However, practical clinical applications are limited by poor understanding interaction mechanism between pulsed and cells, particularly process electroporation its effect on parameter selection. This paper established a multishelled dielectric model based finite elements to simulate analyze processes involved electroporation. In particular, include dynamic...

In vivo studies of tumor-cell apoptosis induced by nanosecond pulsed electric field require high-voltage pulses delivered to the biological tissues. this paper, a newly developed all-solid-state pulse generator based on Marx concept is proposed for application. The comprises four parts: dc charging power, solid-state circuit using metal-oxide-semiconductor field-effect transistors, control field-programmable gate array, and load. This has capability producing repetitive with voltage up 8 kV,...

Frequency response analysis (FRA) has been widely accepted as a diagnostic tool for power transformer winding deformation faults. Typically, both amplitude-frequency and phase-frequency signatures are obtained by an FRA analyzer. However, most existing analyzers use only the information on signature, while is neglected. It also found that in some cases, results do not comply with hard evidence. This paper introduces method based of binary images from to improve outcomes. The digital image...