A5048292939- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Genetic diversity and population structure
- Animal Genetics and Reproduction
- Meat and Animal Product Quality
- Milk Quality and Mastitis in Dairy Cows
- Cancer-related molecular mechanisms research
- melanin and skin pigmentation
- Animal Nutrition and Physiology
- Molecular Biology Techniques and Applications
- Identification and Quantification in Food
- Horticultural and Viticultural Research
- Biochemical Analysis and Sensing Techniques
- Effects of Environmental Stressors on Livestock
- Digestive system and related health
- Regulation of Appetite and Obesity
- Animal Diversity and Health Studies
- Protein Hydrolysis and Bioactive Peptides
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Muscle Physiology and Disorders
- Nuts composition and effects
- Edible Oils Quality and Analysis
- Probiotics and Fermented Foods
- Microbial infections and disease research
University of Molise
2016-2025
Consorzio Milano Ricerche
2022
Manchester City Football Club
2018
University of Perugia
2006
National Institute of Agricultural Botany
2006
Instituto de Agricultura Sostenible
2006
University of Pavia
1992
Among the European countries, Italy counts largest number of local goat breeds. Thanks to recent availability a medium-density SNP (single nucleotide polymorphism) chip for goat, genetic diversity Italian populations was characterized by genotyping samples from 14 breeds that originate different geographical areas with more than 50 000 SNPs evenly distributed on genome. Analysis data revealed high levels polymorphism and an underlying North–south geographic pattern highlighted both first...
Summary The availability of dense single nucleotide polymorphism ( SNP ) assays allows for the determination autozygous segments based on runs consecutive homozygous genotypes ROH ). aim present study was to investigate occurrence and distribution in 21 Italian sheep breeds using medium‐density order characterize autozygosity identify genomic regions that frequently appeared within individuals, namely islands. After filtering, final number animals s retained analyses were 502 46 277...
Variations in body weight and fat distribution are associated with feed quality quantity, thermoregulation energy reserve. Ethiopia is characterised by distinct agro-ecologies human ethnic farmer's diversity of ancient origin which have impacted on the variation its livestock species. Here, we investigate autosomal genome-wide profiles 11 Ethiopian indigenous sheep populations using Illumina Ovine 50K SNP BeadChip assay. Populations from The Caribbean, Europe, Middle East, China western,...
An experimental cattle population was screened for polymorphisms in the leptin gene and five SNPs were found regions containing coding sequences. The association of these with feed intake fat-related traits evaluated. results suggest an between a polymorphism exon 2, described here first time, intake. Individuals genotype A/T at this position had 19% greater mean than individuals A/A. There also evidence link haplotypes some traits.
Merino and Merino-derived sheep breeds have been widely distributed across the world, both as purebred admixed populations. They represent an economically historically important genetic resource which over time has used basis for development of new breeds. In order to examine influence in context a global collection domestic breeds, we analyzed genotype data that were obtained with OvineSNP50 BeadChip (Illumina) 671 individuals from 37 populations, including subset Sheep HapMap dataset....
Italy counts several sheep breeds, arisen over centuries as a consequence of ancient and recent genetic demographic events. To finely reconstruct structure relationships between Italian sheep, 496 subjects from 19 breeds were typed at 50K single nucleotide polymorphism loci. A subset foreign the Sheep HapMap dataset was also included in analyses. Genetic distances (as visualized either network or multidimensional scaling analysis identical by state distances) closely reflected geographic...
Identification of genomic regions that have been targets selection for phenotypic traits is one the most challenging applications dense marker panels in animal genetics. In this study, a genomewide scan using approximately 50,000 SNP was performed an attempt to identify associated with fat deposition sheep, importance not only being limited livestock facing future climate changes but also elucidating physiology lipid metabolism. The genotyping results obtained Ovine SNP50K BeadChip 2 tail...
Ruminant production has been an essential part of human activities worldwide since ancient times. The expected increase in world population and per capita income, with the amount prevalence animal products diet, urbanisation, a concentration urban areas losses supply chain, growing concern over environmental impact farming require long-term global strategy for more intensive sustainable ruminant production. Therefore, solutions to high-quality origin, without harming health, welfare,...
In the last 50 years, diversity of cattle breeds has experienced a severe contraction. However, in spite growing diffusion cosmopolite specialized breeds, several local are still farmed Italy. Genetic characterization represents an essential step to guide decisions management farm animal genetic resources. The aim this work was provide high-resolution representation genome-wide and population structure Italian using medium-density single nucleotide polymorphism (SNP) array.After quality...
To enhance and extend the knowledge about global historical phylogenetic relationships between Merino Merino-derived breeds, 19 populations were genotyped with OvineSNP50 BeadChip specifically for this study, while an additional 23 from publicly available genotypes retrieved. Three complementary statistical tests, Rsb (extended haplotype homozygosity between-populations), XP-EHH (cross-population extended homozygosity), runs of (ROH) islands applied to identify genomic variants potential...
Contradictory results have been reported on the use of goats' milk in cows' allergy. In this study hypothesis was tested, using a guinea pig model allergy, that these discrepancies could be due to high genetic polymorphism proteins. Forty pigs were fed over 20 d period with pelleted diets containing one following: soyabean proteins (group S), CM), GM1) or low GM2) α s1 -casein content. Parenteral sensitization GM1 and GM2 also assessed. The measured (1) by systemic IgG1 antibodies directed...
A set of 11 polymorphic markers (1 cleaved amplified sequence (CAPS), 2 sequence-characterized regions (SCARs), and 8 single-nucleotide polymorphism (SNP) - derived markers) was obtained for olive cultivar identification by comparing DNA sequences from different accessions. Marker development more efficient, using the database rather than cloning arbitrary fragments. Analyses 3 genes diverse cultivars revealed an SNP frequency 1 per 190 base pairs in exons 149 introns. Most mutations were...
Seven microsatellite markers were used to study genetic diversity of three Egyptian (Egyptian Baladi, Barki and Zaraibi) two Italian (Maltese Montefalcone) goat breeds. The microsatellites showed a high polymorphic information content (PIC) more than 0.5 in most the locus-breed combinations indicated that loci useful assessing within- between-breed variability domestic (Capra hircus). expected heterozygosity breeds varied from 0.670 0.792. In geographically wider distributed Baladi breed...
Abstract Water buffalo is a globally important species for agriculture and local economies. A de novo assembled, well-annotated reference sequence the water an prerequisite studying biology of this species, necessary to manage genetic diversity use modern breeding genomic selection techniques. However, no such genome assembly has been previously reported. There are 2 domestic buffalo, river (2n = 50) swamp 48) buffalo. Here we describe draft quality created from Illumina GA Roche 454 short...
Abstract Background Assessment of genetic diversity and population structure provides important control metrics to avoid erosion, inbreeding depression crossbreeding between exotic locally-adapted cattle breeds since these events can have deleterious consequences eventually lead extinction. Historically, the Alpine Arc represents an pocket biodiversity with a large number autochthonous that provide fundamental source income for entire regional economy. By using genotype data from...
Genomic regions subjected to selection frequently show signatures such as within-population reduced nucleotide diversity and outlier values of differentiation among differentially selected populations. In this study, we analyzed 50K SNP genotype data 373 animals belonging 23 sheep breeds different geographic origins using the Rsb (extended haplotype homozygosity) FST statistical approaches, identify loci associated with fat-tail phenotype. We also checked if these putative overlapped...
Abstract Local adaptation of animals to the environment can abruptly become a burden when faced with rapid climatic changes such as those foreseen for Italian peninsula over next 70 years. Our study investigates genetic structure goat populations and links it how genetics might evolve 50 We used one largest national datasets including > 1000 goats from 33 across collected by Goat Consortium genotyped k markers. results showed that be discriminated in three groups reflective geography its...
Abstract Background The presence of goats in the Canary Islands dates back to late 1st millennium BC, which coincides with colonization by Amazigh settlers. However, exact geographic origin Canarian is uncertain since peoples were distributed over a wide spatial range. Nowadays, three breeds (Palmera, Majorera and Tinerfeña) are officially recognized, along two distinct South North Tinerfeña ecotypes, thriving arid dry semi-desertic environments Palmera adapted humid temperate areas that...
Background: The presence of light-pigmented facial stripes, parallel on both sides the cranial region, is a widespread characteristic in various goat breeds European origin and beyond. In Italy, this phenotype relatively common from north to south peninsula. availability genotypic data at single-nucleotide polymorphism (SNP) loci for populations characterized by such pigmentation pattern enabled us study genomic regions potentially correlated with phenotype, simplicity referred as...
Fat tail in sheep represents a valuable energy reserve for facing future climate changes. The identification of genes with role the fat-tail phenotype may contribute to understanding physiology fat deposition and mechanisms adaptation. Genotypic data obtained OvineSNP50K array 13 thin-tail breeds from Italy were used identify selection signatures through pairwise thin- versus breed comparisons, following Mediterranean area: two unique Italian (Barbaresca Laticauda), Barbary Libya, Ossimi...